Homo sapiens (human): 55775 Help Entry 55775             CDS       T01001                                  Symbol TDP1 Name (RefSeq) tyrosyl-DNA phosphodiesterase 1   KO K10862   tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] Organism hsa  Homo sapiens (human) Pathway hsa03410   Base excision repair Network nt06504  Base excision repair   Element N01435   Base excision and strand cleavage by NEIL glycosylase Disease H01891   Autosomal recessive spinocerebellar ataxias H02573   Autosomal recessive spinocerebellar ataxias with axonal neuropathy Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03410 Base excision repair     55775 (TDP1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     55775 (TDP1) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   SSBR (single strand breaks repair)    BER (base exicision repair)     Other BER factors      55775 (TDP1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tyr-DNA_phospho RMMBL Motif Other DBs NCBI-GeneID:  55775 NCBI-ProteinID:  NP_001008744 OMIM:  607198 HGNC:  18884 Ensembl:  ENSG00000042088 UniProt:  Q9NUW8 B3KN41 Structure PDBPDBj LinkDB All DBs Position 14:89954968..90044764 Genome browser AA seq 608 aa AA seqDB search MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT HGNMWVPS NT seq 1827 nt NT seq  +upstreamnt  +downstreamnt atgtctcaggaaggcgattatgggaggtggaccatatctagtagtgatgaaagtgaggaa gaaaagccaaaaccagacaagccatctacctcttctcttctctgtgccaggcaaggagca gcaaatgagcccaggtacacctgttccgaggcccagaaagctgcacacaagaggaaaata tcacctgtgaaattcagcaatacagattcagttttacctcccaaaaggcagaaaagcggt tcccaggaggacctcggctggtgtctgtccagcagtgatgatgagctgcaaccagaaatg ccgcagaagcaggctgagaaagtggtgatcaaaaaggagaaagacatctctgctcccaat gacggcactgcccaaagaactgaaaatcatggcgctcccgcctgccacaggctcaaagag gaggaagacgagtatgagacatcaggggagggccaggacatttgggacatgctggataaa gggaaccccttccagttttacctcactagagtctctggagttaagccaaagtataactct ggagccctccacatcaaggatattttatctcctttatttgggacgcttgtttcttcagct cagtttaactactgctttgacgtggactggctcgtaaaacagtatccaccagagttcagg aagaagccaatcctgcttgtgcatggtgataagcgagaggctaaggctcacctccatgcc caggccaagccttacgagaacatctctctctgccaggcaaagttggatattgcgtttgga acacaccacacgaaaatgatgctgctgctctatgaagaaggcctccgggttgtcatacac acctccaacctcatccatgctgactggcaccagaaaactcaaggaatatggttgagcccc ttatacccacgaattgctgatggaacccacaaatctggagagtcgccaacacattttaaa gctgatctcatcagttacttgatggcttataatgccccttctctcaaggagtggatagat gtcattcacaagcacgatctctctgaaacaaatgtttatcttattggttcaaccccagga cgctttcaaggaagtcaaaaagataattggggacattttagacttaagaagcttctgaaa gaccatgcctcatccatgcctaacgcagagtcctggcctgtcgtaggtcagttttcaagc gttggctccttgggagccgatgaatcaaagtggttatgttctgagtttaaagagagcatg ctgacactggggaaggaaagcaagactccaggaaaaagctctgttcctctttacttgatc tatccttctgtggaaaatgtgcggaccagtttagaaggatatcctgctgggggctctctt ccctatagcatccagacagctgaaaaacagaattggctgcattcctattttcacaaatgg tcagctgagacttctggccgcagcaatgccatgccacatattaagacatatatgaggcct tctccagacttcagtaaaattgcttggttccttgtcacaagcgcaaatctgtccaaggct gcctggggagcattggagaagaatggcacccagctgatgatccgctcctacgagctcggg gtccttttcctcccttcagcatttggtctagacagtttcaaagtgaaacagaagttcttc gctggcagccaggagccaatggccacctttcctgtgccatatgatttgcctccagaactg tatggaagtaaagatcggccatggatatggaacattccttatgtcaaagcaccggatacg catgggaacatgtgggtgccctcctga

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