| Entry |
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| Name |
Base excision and strand cleavage by NEIL glycosylase
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| Definition |
glycosylase -> TDP1+PNKP == POLB+XRCC1 == PARP |
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| Expanded |
79661,252969,55247 -> 55775+11284 == 5423+7515 == 142,10038 |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 79661 | NEIL1; nei like DNA glycosylase 1 |
| 252969 | NEIL2; nei like DNA glycosylase 2 |
| 55247 | NEIL3; nei like DNA glycosylase 3 |
| 55775 | TDP1; tyrosyl-DNA phosphodiesterase 1 |
| 11284 | PNKP; polynucleotide kinase 3'-phosphatase |
| 5423 | POLB; DNA polymerase beta |
| 7515 | XRCC1; X-ray repair cross complementing 1 |
| 142 | PARP1; poly(ADP-ribose) polymerase 1 |
| 10038 | PARP2; poly(ADP-ribose) polymerase 2 |
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| Reference |
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| Authors |
Grundy GJ, Parsons JL |
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| Title |
Base excision repair and its implications to cancer therapy. |
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| Journal |
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| Reference |
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| Authors |
Horton JK, Stefanick DF, Zhao ML, Janoshazi AK, Gassman NR, Seddon HJ, Wilson SH |
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| Title |
XRCC1-mediated repair of strand breaks independent of PNKP binding. |
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| Journal |
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| Reference |
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| Authors |
Lebedeva NA, Rechkunova NI, Lavrik OI |
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| Title |
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1. |
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| Journal |
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| LinkDB |
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