Homo sapiens (human): 5654
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Entry
5654 CDS
T01001
Symbol
HTRA1, ARMD7, CADASIL2, CARASIL, HtrA, L56, ORF480, PRSS11
Name
(RefSeq) HtrA serine peptidase 1
KO
K08784
HtrA serine peptidase 1 [EC:3.4.21.-]
Organism
hsa
Homo sapiens (human)
Disease
H00536
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy
H00821
Age-related macular degeneration
H01757
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
Drug target
Galegenimab:
D12379
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
5654 (HTRA1)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hsa03110
]
5654 (HTRA1)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
5654 (HTRA1)
Chaperones and folding catalysts [BR:
hsa03110
]
Other chaperones and cochaperones
DegP / HtrA
5654 (HTRA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin_2
Trypsin
PDZ_6
PDZ
IGFBP
PDZ_2
Kazal_2
Peptidase_S46
Kazal_1
Peptidase_S32
DUF150_C
LSM
DUF6288
Motif
Other DBs
NCBI-GeneID:
5654
NCBI-ProteinID:
NP_002766
OMIM:
602194
HGNC:
9476
Ensembl:
ENSG00000166033
UniProt:
Q92743
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:122461553..122514907
Genome browser
AA seq
480 aa
AA seq
DB search
MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARD
ACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCG
SDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIA
PAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEA
KIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTT
QRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKI
KKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPD
TPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgcagatcccgcgcgccgctcttctcccgctgctgctgctgctgctggcggcgcccgcc
tcggcgcagctgtcccgggccggccgctcggcgcctttggccgccgggtgcccagaccgc
tgcgagccggcgcgctgcccgccgcagccggagcactgcgagggcggccgggcccgggac
gcgtgcggctgctgcgaggtgtgcggcgcgcccgagggcgccgcgtgcggcctgcaggag
ggcccgtgcggcgaggggctgcagtgcgtggtgcccttcggggtgccagcctcggccacg
gtgcggcggcgcgcgcaggccggcctctgtgtgtgcgccagcagcgagccggtgtgcggc
agcgacgccaacacctacgccaacctgtgccagctgcgcgccgccagccgccgctccgag
aggctgcaccggccgccggtcatcgtcctgcagcgcggagcctgcggccaagggcaggaa
gatcccaacagtttgcgccataaatataactttatcgcggacgtggtggagaagatcgcc
cctgccgtggttcatatcgaattgtttcgcaagcttccgttttctaaacgagaggtgccg
gtggctagtgggtctgggtttattgtgtcggaagatggactgatcgtgacaaatgcccac
gtggtgaccaacaagcaccgggtcaaagttgagctgaagaacggtgccacttacgaagcc
aaaatcaaggatgtggatgagaaagcagacatcgcactcatcaaaattgaccaccagggc
aagctgcctgtcctgctgcttggccgctcctcagagctgcggccgggagagttcgtggtc
gccatcggaagcccgttttcccttcaaaacacagtcaccaccgggatcgtgagcaccacc
cagcgaggcggcaaagagctggggctccgcaactcagacatggactacatccagaccgac
gccatcatcaactatggaaactcgggaggcccgttagtaaacctggacggtgaagtgatt
ggaattaacactttgaaagtgacagctggaatctcctttgcaatcccatctgataagatt
aaaaagttcctcacggagtcccatgaccgacaggccaaaggaaaagccatcaccaagaag
aagtatattggtatccgaatgatgtcactcacgtccagcaaagccaaagagctgaaggac
cggcaccgggacttcccagacgtgatctcaggagcgtatataattgaagtaattcctgat
accccagcagaagctggtggtctcaaggaaaacgacgtcataatcagcatcaatggacag
tccgtggtctccgccaatgatgtcagcgacgtcattaaaagggaaagcaccctgaacatg
gtggtccgcaggggtaatgaagatatcatgatcacagtgattcccgaagaaattgaccca
tag
DBGET
integrated database retrieval system
