Homo sapiens (human): 5788
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Entry
5788 CDS
T01001
Symbol
PTPRC, B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200
Name
(RefSeq) protein tyrosine phosphatase receptor type C
KO
K06478
receptor-type tyrosine-protein phosphatase C [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04514
Cell adhesion molecules
hsa04660
T cell receptor signaling pathway
hsa04666
Fc gamma R-mediated phagocytosis
hsa05132
Salmonella infection
hsa05340
Primary immunodeficiency
Disease
H00091
T-B+Severe combined immunodeficiency
H00413
Hepatitis C
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
5788 (PTPRC)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
5788 (PTPRC)
04666 Fc gamma R-mediated phagocytosis
5788 (PTPRC)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
5788 (PTPRC)
09163 Immune disease
05340 Primary immunodeficiency
5788 (PTPRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5788 (PTPRC)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
5788 (PTPRC)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
5788 (PTPRC)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
5788 (PTPRC)
CD molecules [BR:
hsa04090
]
Proteins
5788 (PTPRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
CD45
fn3
PTP_N
Y_phosphatase3
PTPlike_phytase
DSPc
GnsAB_toxin
TM231
Motif
Other DBs
NCBI-GeneID:
5788
NCBI-ProteinID:
NP_002829
OMIM:
151460
HGNC:
9666
Ensembl:
ENSG00000081237
UniProt:
P08575
Structure
PDB
LinkDB
All DBs
Position
1:198638713..198757476
Genome browser
AA seq
1306 aa
AA seq
DB search
MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPA
STFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQTPSA
GTDTQTFSGSAANAKLNPTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAAL
PARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYL
YNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVP
PGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLE
PEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFH
NFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTT
KSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFR
VKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYK
IYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAEFQSI
PRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPR
KYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVV
VKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNA
FSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEA
QYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ
HIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINA
SFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK
QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISM
IQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQV
VKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDKVKQDAN
CVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
NT seq
3921 nt
NT seq
+upstream
nt +downstream
nt
atgaccatgtatttgtggcttaaactcttggcatttggctttgcctttctggacacagaa
gtatttgtgacagggcaaagcccaacaccttcccccactggattgactacagcaaagatg
cccagtgttccactttcaagtgaccccttacctactcacaccactgcattctcacccgca
agcacctttgaaagagaaaatgacttctcagagaccacaacttctcttagtccagacaat
acttccacccaagtatccccggactctttggataatgctagtgcttttaataccacaggt
gtttcatcagtacagacgcctcaccttcccacgcacgcagactcgcagacgccctctgct
ggaactgacacgcagacattcagcggctccgccgccaatgcaaaactcaaccctacccca
ggcagcaatgctatctcagatgtcccaggagagaggagtacagccagcacctttcctaca
gacccagtttccccattgacaaccaccctcagccttgcacaccacagctctgctgcctta
cctgcacgcacctccaacaccaccatcacagcgaacacctcagatgcctaccttaatgcc
tctgaaacaaccactctgagcccttctggaagcgctgtcatttcaaccacaacaatagct
actactccatctaagccaacatgtgatgaaaaatatgcaaacatcactgtggattactta
tataacaaggaaactaaattatttacagcaaagctaaatgttaatgagaatgtggaatgt
ggaaacaatacttgcacaaacaatgaggtgcataaccttacagaatgtaaaaatgcgtct
gtttccatatctcataattcatgtactgctcctgataagacattaatattagatgtgcca
ccaggggttgaaaagtttcagttacatgattgtacacaagttgaaaaagcagatactact
atttgtttaaaatggaaaaatattgaaacctttacttgtgatacacagaatattacctac
agatttcagtgtggtaatatgatatttgataataaagaaattaaattagaaaaccttgaa
cccgaacatgagtataagtgtgactcagaaatactctataataaccacaagtttactaac
gcaagtaaaattattaaaacagattttgggagtccaggagagcctcagattattttttgt
agaagtgaagctgcacatcaaggagtaattacctggaatccccctcaaagatcatttcat
aattttaccctctgttatataaaagagacagaaaaagattgcctcaatctggataaaaac
ctgatcaaatatgatttgcaaaatttaaaaccttatacgaaatatgttttatcattacat
gcctacatcattgcaaaagtgcaacgtaatggaagtgctgcaatgtgtcatttcacaact
aaaagtgctcctccaagccaggtctggaacatgactgtctccatgacatcagataatagt
atgcatgtcaagtgtaggcctcccagggaccgtaatggcccccatgaacgttaccatttg
gaagttgaagctggaaatactctggttagaaatgagtcgcataagaattgcgatttccgt
gtaaaagatcttcaatattcaacagactacacttttaaggcctattttcacaatggagac
tatcctggagaaccctttattttacatcattcaacatcttataattctaaggcactgata
gcatttctggcatttctgattattgtgacatcaatagccctgcttgttgttctctacaaa
atctatgatctacataagaaaagatcctgcaatttagatgaacagcaggagcttgttgaa
agggatgatgaaaaacaactgatgaatgtggagccaatccatgcagatattttgttggaa
acttataagaggaagattgctgatgaaggaagactttttctggctgaatttcagagcatc
ccgcgggtgttcagcaagtttcctataaaggaagctcgaaagccctttaaccagaataaa
aaccgttatgttgacattcttccttatgattataaccgtgttgaactctctgagataaac
ggagatgcagggtcaaactacataaatgccagctatattgatggtttcaaagaacccagg
aaatacattgctgcacaaggtcccagggatgaaactgttgatgatttctggaggatgatt
tgggaacagaaagccacagttattgtcatggtcactcgatgtgaagaaggaaacaggaac
aagtgtgcagaatactggccgtcaatggaagagggcactcgggcttttggagatgttgtt
gtaaagatcaaccagcacaaaagatgtccagattacatcattcagaaattgaacattgta
aataaaaaagaaaaagcaactggaagagaggtgactcacattcagttcaccagctggcca
gaccacggggtgcctgaggatcctcacttgctcctcaaactgagaaggagagtgaatgcc
ttcagcaatttcttcagtggtcccattgtggtgcactgcagtgctggtgttgggcgcaca
ggaacctatatcggaattgatgccatgctagaaggcctggaagccgagaacaaagtggat
gtttatggttatgttgtcaagctaaggcgacagagatgcctgatggttcaagtagaggcc
cagtacatcttgatccatcaggctttggtggaatacaatcagtttggagaaacagaagtg
aatttgtctgaattacatccatatctacataacatgaagaaaagggatccacccagtgag
ccgtctccactagaggctgaattccagagacttccttcatataggagctggaggacacag
cacattggaaatcaagaagaaaataaaagtaaaaacaggaattctaatgtcatcccatat
gactataacagagtgccacttaaacatgagctggaaatgagtaaagagagtgagcatgat
tcagatgaatcctctgatgatgacagtgattcagaggaaccaagcaaatacatcaatgca
tcttttataatgagctactggaaacctgaagtgatgattgctgctcagggaccactgaag
gagaccattggtgacttttggcagatgatcttccaaagaaaagtcaaagttattgttatg
ctgacagaactgaaacatggagaccaggaaatctgtgctcagtactggggagaaggaaag
caaacatatggagatattgaagttgacctgaaagacacagacaaatcttcaacttatacc
cttcgtgtctttgaactgagacattccaagaggaaagactctcgaactgtgtaccagtac
caatatacaaactggagtgtggagcagcttcctgcagaacccaaggaattaatctctatg
attcaggtcgtcaaacaaaaacttccccagaagaattcctctgaagggaacaagcatcac
aagagtacacctctactcattcactgcagggatggatctcagcaaacgggaatattttgt
gctttgttaaatctcttagaaagtgcggaaacagaagaggtagtggatatttttcaagtg
gtaaaagctctacgcaaagctaggccaggcatggtttccacattcgagcaatatcaattc
ctatatgacgtcattgccagcacctaccctgctcagaatggacaagtaaagaaaaacaac
catcaagaagataaaattgaatttgataatgaagtggacaaagtaaagcaggatgctaat
tgtgttaatccacttggtgccccagaaaagctccctgaagcaaaggaacaggctgaaggt
tctgaacccacgagtggcactgaggggccagaacattctgtcaatggtcctgcaagtcca
gctttaaatcaaggttcatag
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integrated database retrieval system
