Entry |
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Symbol |
PTPRC, CD45
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Name |
receptor-type tyrosine-protein phosphatase C [EC: 3.1.3.48]
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Pathway |
map04660 | T cell receptor signaling pathway |
map04666 | Fc gamma R-mediated phagocytosis |
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Disease |
H00091 | T-B+Severe combined immunodeficiency |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
04666 Fc gamma R-mediated phagocytosis
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
09163 Immune disease
05340 Primary immunodeficiency
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
09183 Protein families: signaling and cellular processes
04090 CD molecules
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
Protein phosphatases and associated proteins [BR:ko01009]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C
CD molecules [BR:ko04090]
Proteins
K06478 CD45, PTPRC; protein tyrosine phosphatase, receptor type, C
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Streuli M, Hall LR, Saga Y, Schlossman SF, Saito H |
Title |
Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens. |
Journal |
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Sequence |
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Reference |
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Authors |
Hermiston ML, Xu Z, Weiss A |
Title |
CD45: a critical regulator of signaling thresholds in immune cells. |
Journal |
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Reference |
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Authors |
Charbonneau H, Tonks NK, Walsh KA, Fischer EH |
Title |
The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. |
Journal |
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Sequence |
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LinkDB |
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