Homo sapiens (human): 5800
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Entry
5800 CDS
T01001
Symbol
PTPRO, GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
Name
(RefSeq) protein tyrosine phosphatase receptor type O
KO
K18035
receptor-type tyrosine-protein phosphatase O [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Disease
H01657
Nephrotic syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5800 (PTPRO)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
5800 (PTPRO)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
5800 (PTPRO)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
fn3
Ig_DSCAM-DSCAML_C
Tc-R-P
PTP-SAK
PTP-NADK
DSPc
Y_phosphatase3
PTPlike_phytase
Fn3_Dep-1_1st
Motif
Other DBs
NCBI-GeneID:
5800
NCBI-ProteinID:
NP_109592
OMIM:
600579
HGNC:
9678
Ensembl:
ENSG00000151490
UniProt:
Q16827
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:15322508..15598331
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AA seq
1216 aa
AA seq
DB search
MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
QQFCISDVIYENVSKS
NT seq
3651 nt
NT seq
+upstream
nt +downstream
nt
atggggcacctgcccacggggatacacggcgcccgccgcctcctgcctctgctctggctc
tttgtgctgttcaagaatgctacagctttccatgtaactgtccaagatgataataacatc
gttgtctcattagaagcttcagacgtcatcagtccagcatctgtgtatgttgtgaagata
actggtgaatccaaaaattatttcttcgaatttgaggaattcaacagcactttgcctcct
cctgttattttcaaggccagttatcatggcctttattatataatcactctggtagtggta
aatggaaatgtggtgaccaagccatccagatcaatcactgtgttaacaaaacctctacct
gtaaccagtgtttccatatatgactataaaccttctcctgaaacaggagtcctgtttgaa
atacattatccagaaaaatataacgttttcacaagagtgaacattagctactgggaaggt
aaagacttccggacaatgctatataaagatttctttaagggaaaaacagtatttaatcac
tggctgccaggaatgtgttatagtaatatcacctttcagctggtatctgaggcaactttt
aataaaagtacccttgttgagtacagtggtgtcagtcacgaacccaaacagcacagaact
gccccttatccacctcaaaatatttccgttcgtatcgtaaacttgaacaaaaacaactgg
gaagaacagagtggcaatttcccagaagaatccttcatgagatcacaagatacaatagga
aaagaaaaactcttccattttacagaagaaacccctgaaattccctcgggcaacatttct
tccggttggcctgattttaatagcagtgactatgaaactacgtctcagccatattggtgg
gacagtgcatctgcagctcctgaaagtgaagatgaatttgtcagcgtacttcccatggaa
tacgaaaataacagtacactcagtgagacagagaagtcaacatcaggctctttctccttt
ttccctgtgcaaatgatattgacctggttaccacccaaaccacccactgcttttgatggg
ttccatatccatattgaacgagaagagaactttactgaatatttgatggtggatgaagaa
gcacatgaatttgttgcagaactgaaggaacctgggaaatataagttatctgtgacaacc
tttagttcctcaggatcttgtgaaactcgaaaaagtcagtcagcaaaatcactcagcttt
tatatcagtccttcaggagagtggattgaagaactgaccgagaagccgcagcacgtgagt
gtccacgttttaagctcaaccactgccttgatgtcctggacatcttcccaagagaactac
aacagcaccattgtgtctgtggtgtcgctgacctgccagaaacaaaaggagagccagagg
cttgaaaagcagtactgcactcaggtgaactcaagcaaacctattattgaaaatctggtt
cctggtgcccagtaccaggttgtaatatacctaaggaaaggccctttgattggaccacct
tcagatcctgtgacatttgctattgttcccacaggaataaaggatttaatgctctatcct
ttgggtcctacggccgtggttctgagctggaccagaccttatttaggcgtgttcagaaaa
tacgtggttgaaatgttttatttcaaccctgctacaatgacatcagagtggaccacctac
tatgaaatagcagcaactgtttccttaactgcatccgtgagaatagctaatctgctgcca
gcatggtactacaacttccgggttaccatggtgacgtggggagatccagaattgagctgc
tgtgacagctctaccatcagcttcataacagccccagtggctccggaaatcacttctgtg
gaatatttcaacagtctgttatatatcagttggacatatggggatgatacaacggacttg
tcccattctagaatgcttcactggatggtggttgcagaaggaaaaaagaaaattaaaaag
agtgtaacacgcaatgtcatgactgcaattctcagcttgcctccaggcgacatctataac
ctctcagtaactgcttgtactgaaagaggaagtaatacctccatgctccgccttgtcaag
ctagaaccagctccacccaaatcactcttcgcagtgaacaaaacccagacttcagtgact
ttgctgtgggtggaagagggagtagctgatttctttgaagttttctgtcaacaagttggc
tccagtcagaaaaccaaacttcaggaaccagttgctgtttcttcccatgtcgtgaccatc
tccagccttcttcctgccactgcctacaattgtagtgtcaccagctttagccatgacagc
cccagtgtccctacgttcatagccgtctcaacaatggttacagagatgaatcccaatgtg
gtagtgatctccgtgctggccatccttagcacacttttaattggactgttgcttgttacc
ctcattattcttaggaaaaagcatctgcagatggctagggagtgtggagctggtacattt
gtcaattttgcatccttagagagggatggaaagcttccatacaactggcgtaggagtata
tttgctttcttaaccctgctaccctcatgtctttggactgattatcttttggcattttat
attaatccttggagtaaaaatggtttaaagaagaggaaactgacaaacccggttcaactg
gatgactttgatgcctatattaaggatatggccaaagactctgactataaattttctctt
cagtttgaggagttgaaattgattggactggatatcccacactttgctgcagatcttcca
ctgaatcgatgtaaaaaccgttacacaaacatcctaccatatgacttcagccgtgtgaga
ttagtctccatgaatgaagaggaaggtgcagactacatcaatgccaactatattcctgga
tacaactcaccccaggagtatattgccacccaggggccactgcctgaaaccagaaatgac
ttctggaagatggtcctgcaacaaaagtctcagattattgtcatgctcactcagtgtaat
gagaaaaggagggtgaaatgtgaccattactggccattcacggaagaacctatagcctat
ggagacatcactgtggagatgatttcagaggaagagcaggacgactgggcctgtagacac
ttccggatcaactatgctgacgagatgcaggatgtgatgcattttaactacactgcatgg
cctgatcatggtgtgcccacagcaaatgctgcagaaagtatcctgcagtttgtacacatg
gtccgacagcaagctaccaagagcaaaggtcccatgatcattcactgcagtgctggcgtg
ggacggacaggaacattcattgccctggacaggctcttgcagcacattcgggatcatgag
tttgttgacatcttagggctggtgtcagaaatgaggtcataccggatgtctatggtacag
acagaggagcagtacatttttatccatcagtgtgtgcaactgatgtggatgaagaagaag
cagcagttctgcatcagtgatgtcatatacgagaatgttagcaagtcctag
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integrated database retrieval system
