KEGG   Homo sapiens (human): 60528
Entry
60528             CDS       T01001                                 
Symbol
ELAC2, COXPD17, ELC2, HPC2
Name
(RefSeq) elaC ribonuclease Z 2
  KO
K00784  ribonuclease Z [EC:3.1.26.11]
Organism
hsa  Homo sapiens (human)
Disease
H00891  Combined oxidative phosphorylation deficiency
H02530  Hereditary prostate cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    60528 (ELAC2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.26  Endoribonucleases producing 5'-phosphomonoesters
    3.1.26.11  tRNase Z
     60528 (ELAC2)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  3'processing and CCA adding factors
   3'processing factors
    60528 (ELAC2)
 Prokaryotic type
    60528 (ELAC2)
SSDB
Motif
Pfam: Lactamase_B_4 Lactamase_B_2 Anti-Pycsar_Apyc1 Lactamase_B
Other DBs
NCBI-GeneID: 60528
NCBI-ProteinID: NP_060597
OMIM: 605367
HGNC: 14198
Ensembl: ENSG00000006744
UniProt: Q9BQ52 A0A0S2Z5M8
Structure
LinkDB
Position
17:complement(12991612..13018027)
AA seq 826 aa
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYL
QVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGG
LSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTV
YQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLV
VAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPP
DPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMER
FGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGE
CLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQY
PEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLA
AVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLH
HISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWK
VVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFI
MLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEE
RREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
NT seq 2481 nt   +upstreamnt  +downstreamnt
atgtgggcgctttgctcgctgctgcggtccgcggccggacgcaccatgtcgcagggacgc
accatatcgcaggcacccgcccgccgcgagcggccgcgcaaggacccgctgcggcacctg
cgcacgcgagagaagcgcggaccgtcggggtgctccggcggcccaaacaccgtgtacctg
caggtggtggcagcgggtagccgggactcgggcgccgcgctctacgtcttctccgagttc
aaccggtatctcttcaactgtggagaaggcgttcagagactcatgcaggagcacaagtta
aaggttgctcgcctggacaacatattcctgacacgaatgcactggtctaatgttgggggc
ttaagtggaatgattcttactttaaaggaaaccgggcttccaaagtgtgtactttctgga
cctccacaactggaaaaatacctcgaagcaatcaaaatattttctggtccattgaaagga
atagaactggctgtgcggccccactctgccccagaatacgaggatgaaaccatgacagtt
taccagatccccatacacagtgaacagaggaggggaaagcaccaaccatggcagagtcca
gaaaggcctctcagcaggctcagtccagagcgatcttcagactccgagtcgaatgaaaat
gagccacaccttccacatggtgttagccagagaagaggggtcagggactcttccctggtc
gtagctttcatctgtaagcttcacttaaagagaggaaacttcttggtgctcaaagcaaag
gagatgggcctcccagttgggacagctgccatcgctcccatcattgctgctgtcaaggac
gggaaaagcatcactcatgaaggaagagagattttggctgaagagctgtgtactcctcca
gatcctggtgctgcttttgtggtggtagaatgtccagatgaaagcttcattcaacccatc
tgtgagaatgccacctttcagaggtaccaaggaaaggcagatgcccccgtggccttggtg
gttcacatggccccagcatctgtgcttgtggacagcaggtaccagcagtggatggagagg
tttgggcctgacacccagcacttggtcctgaatgagaactgtgcctcagttcacaacctt
cgcagccacaagattcaaacccagctcaacctcatccacccggacatcttccccctgctc
accagtttccgctgtaagaaggagggccccaccctcagtgtgcccatggttcagggtgaa
tgcctcctcaagtaccagctccgtcccaggagggagtggcagagggatgccattattact
tgcaatcctgaggaattcatagttgaggcgctgcagcttcccaacttccagcagagcgtg
caggagtacaggaggagtgcgcaggacggcccagccccagcagagaaaagaagtcagtac
ccagaaatcatcttccttggaacagggtctgccatcccgatgaagattcgaaatgtcagt
gccacacttgtcaacataagccccgacacgtctctgctactggactgtggtgagggcaca
tttgggcagctgtgccgtcattacggagaccaggtggacagggtcctgggcaccctggct
gctgtgtttgtgtcccacctgcacgcagatcaccacacgggcttgccaagtatcttgctg
cagagagaacgcgccttggcatctttgggaaagccgcttcaccctttgctggtggttgcc
cccaaccagctcaaagcctggctccagcagtaccacaaccagtgccaggaggtcctgcac
cacatcagtatgattcctgccaaatgccttcaggaaggggctgagatctccagtcctgca
gtggaaagattgatcagttcgctgttgcgaacatgtgatttggaagagtttcagacctgt
ctggtgcggcactgcaagcatgcgtttggctgtgcgctggtgcacacctctggctggaaa
gtggtctattccggggacaccatgccctgcgaggctctggtccggatggggaaagatgcc
accctcctgatacatgaagccaccctggaagatggtttggaagaggaagcagtggaaaag
acacacagcacaacgtcccaagccatcagcgtggggatgcggatgaacgcggagttcatt
atgctgaaccacttcagccagcgctatgccaaggtccccctcttcagccccaacttcagc
gagaaagtgggagttgcctttgaccacatgaaggtctgctttggagactttccaacaatg
cccaagctgattcccccactgaaagccctgtttgctggcgacatcgaggagatggaggag
cgcagggagaagcgggagctgcggcaggtgcgggcggccctcctgtccagggagctggca
ggcggcctggaggatggggagcctcagcagaagcgggcccacacagaggagccacaggcc
aagaaggtcagagcccagtga

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