Homo sapiens (human): 63976
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Entry
63976 CDS
T01001
Symbol
PRDM16, CMD1LL, KMT8F, LVNC8, MEL1, PFM13
Name
(RefSeq) PR/SET domain 16
KO
K22410
[histone H3]-lysine9 N-methyltransferase [EC:
2.1.1.367
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00310
Lysine degradation
hsa01100
Metabolic pathways
hsa04714
Thermogenesis
Disease
H00294
Dilated cardiomyopathy
H01216
Left ventricular noncompaction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
63976 (PRDM16)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
63976 (PRDM16)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
63976 (PRDM16)
03036 Chromosome and associated proteins [BR:
hsa03036
]
63976 (PRDM16)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.367 [histone H3]-lysine9 N-methyltransferase
63976 (PRDM16)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Zinc finger
Cys2His2 PRDM
63976 (PRDM16)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
63976 (PRDM16)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C2H2
zf-H2C2_2
zf-C2H2_4
PRDM2_PR
zf-C2H2_jaz
zf-C2H2_6
SET
zf-C2H2_11
zf-H2C2_5
C2CH-3rd_BIRD-IDD
Zap1_zf1
zf-BED
C2CH-4th_BIRD-IDD
zf-C2H2_15
Motif
Other DBs
NCBI-GeneID:
63976
NCBI-ProteinID:
NP_071397
OMIM:
605557
HGNC:
14000
Ensembl:
ENSG00000142611
UniProt:
Q9HAZ2
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:3069203..3438621
Genome browser
AA seq
1276 aa
AA seq
DB search
MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN
HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
TGATSESGAFHPINHL
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
atgcgatccaaggcgagggcgaggaagctagccaaaagtgacggtgacgttgtaaataat
atgtatgagcccaaccgggacctgctggccagccacagcgcggaggacgaggccgaggac
agtgccatgtcgcccatccccgtggggccaccgtcccccttccccaccagcgaggacttc
acccccaaggagggctcgccgtacgaggcccctgtctacattcctgaagacattccgatc
ccagcagacttcgagctccgagagtcctccatcccaggggctggcctgggggtctgggcc
aagaggaagatggaagccggggagaggctgggcccctgcgtggtggtgccccgggcggcg
gcaaaggagacagacttcggatgggagcaaatactgacggacgtggaagtgtcgccccag
gaaggctgcatcacaaagatctccgaagacctgggcagtgagaagttctgcgtggatgca
aatcaggcgggggctggcagctggctcaagtacatccgtgtggcgtgctcctgcgatgac
cagaacctcaccatgtgtcagatcagtgagcagatttactataaagtcattaaggacatt
gagccaggtgaggagctgctggtgcacgtgaaggaaggcgtctaccccctgggcacagtg
ccgcccggcctggacgaggagcccacgttccgctgtgacgagtgtgacgaactcttccag
tccaagctggacctgcggcgccataagaagtacacgtgtggctcagtgggggctgcgctc
tacgagggcctggctgaggagctcaagcccgagggccttggcggtggcagcggccaagcc
cacgagtgcaaggactgcgagcggatgttccccaacaagtacagcctggagcagcacatg
gtcatccacacggaggagcgcgagtacaaatgcgaccagtgtcccaaggccttcaactgg
aagtccaacctcatccgccaccagatgtcccacgacagcggcaaacgcttcgaatgtgaa
aactgcgtgaaggtgttcacggaccccagcaaccttcagcggcacatccgctcgcagcac
gtgggcgctcgggcccacgcctgccccgactgcgggaagaccttcgccacgtcctccggc
ctcaagcagcacaagcatatccacagcacggtgaagcctttcatatgtgaggtctgccac
aagtcctacacgcagttctccaacctgtgccggcacaagcggatgcacgccgactgccgc
acgcagatcaagtgcaaggactgtggccagatgttcagcactacctcctccctcaacaag
caccggcgcttctgcgagggcaagaaccattacacgccgggcggcatctttgccccgggc
ctgcccttgacccccagccccatgatggacaaggcaaaaccctcccccagcctcaatcac
gccagcctgggcttcaacgagtactttccctccaggccgcacccggggagcctgcccttc
tccacggcgcctcccacgttccccgcactcacccccggcttcccgggcatcttccctcca
tccttgtacccccggccgcctctgctacctcccacatcgctgctcaagagccccctgaac
cacacccaggacgccaagctccccagtcccctggggaacccagccctgcccctggtctcc
gccgtcagcaacagcagccagggcacgacggcagctgcggggcccgaggagaagttcgag
agccgcctggaggactcctgtgtggagaagctgaagaccaggagcagcgacatgtcggac
ggcagtgactttgaggacgtcaacaccaccacggggaccgacctggacacgaccacgggg
acgggctcggacctggacagcgacgtggacagcgaccctgacaaggacaagggcaagggc
aagtccgccgagggccagcccaagtttgggggcggcttggcgcccccgggggccccgaac
agcgtggccgaggtgcctgtcttctattcccagcactcattcttcccgccacccgacgag
cagctgctgactgcaacgggcgccgccggggactccatcaaggccatcgcatccattgcc
gagaagtactttggccccggcttcatggggatgcaggagaagaagctgggctcgctcccc
taccactcggcgttccccttccagttcctgcccaacttcccccactccctttaccccttc
acggaccgagccctcgcccacaacttgctggtcaaggccgagccaaagtcaccccgggac
gccctcaaggtgggcggccccagtgccgagtgcccctttgatctcaccaccaagcccaaa
gacgtgaagcccatcctgcccatgcccaagggcccctcggcccccgcatccggcgaggag
cagccgctggacctgagcatcggcagccgggcccgtgccagccaaaacggcggcgggcgg
gagccccgcaagaaccacgtctatggggaacgcaagctgggcgccggcgaggggctgccc
caggtgtgcccggcgcggatgccccagcagcccccgctccactacgccaagccctcgccc
ttcttcatggaccccatctacagcagggtagaaaagcggaaggtcacagaccccgtggga
gccctgaaggagaagtacctgcggccgtccccgctgctcttccacccccagatgtcagcc
atagagaccatgacagagaagctggagagctttgcagccatgaaggcggactcgggcagc
tccctgcagcccctcccccaccaccccttcaacttccggtccccacccccaacgctctcc
gaccccatcctcaggaagggcaaggagcgatacacgtgcaggtactgtgggaagatcttc
cccagatcagccaatctcaccagacacctgaggacgcacactggggagcagccgtacagg
tgtaagtactgcgaccgctccttcagcatctcttcgaacctccagcggcacgtccggaac
atccacaacaaggagaagcctttcaagtgccacctgtgcaaccgctgcttcgggcagcag
accaacctggaccggcacctcaagaagcacgagcacgagaacgcaccagtgagccagcac
cccggggtcctcacgaaccacctggggaccagcgcgtcctctcccacctcagagtcggac
aaccacgcacttttagacgagaaagaagactcttatttctcggaaatcagaaactttatt
gccaatagtgagatgaaccaagcatcaacgcgaacagagaaacgggcggacatgcagatc
gtggacggcagtgcccagtgtccaggcctagccagtgagaagcaggaggacgtggaggag
gaggacgacgatgacctggaggaggacgatgaggacagcctggccgggaagtcgcaggat
gacaccgtgtcccccgcacccgagccccaggccgcctacgaggatgaggaggatgaggag
ccagccgcctccctggccgtgggctttgaccacacccgaaggtgtgctgaggaccacgaa
ggcggtctgttagctttggagccgatgccgacttttgggaaggggctggacctccgcaga
gcagctgaggaagcatttgaagttaaagatgtgcttaattccaccttagattctgaggct
ttaaaacatacactgtgcaggcaggctaagaaccaggcatatgcaatgatgctgtccctt
tccgaagacactcctctccacaccccctcccagggttctctggacgcttggttgaaggtc
actggagccacgtcggagtctggagcatttcaccccatcaaccacctctga
DBGET
integrated database retrieval system
