| Entry |
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| Symbol |
NOD2, ACUG, BLAU, BLAUS, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, YAOS
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| Name |
(RefSeq) nucleotide binding oligomerization domain containing 2
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| KO |
| K10165 | nucleotide-binding oligomerization domain-containing protein 2 |
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| Organism |
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| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
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| Network |
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| Element |
| N00940 | NOD-NFKB signaling pathway |
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| Disease |
| H01227 | Inflammatory bowel disease (IBD) |
| H01309 | Sarcoidosis, early-onset |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
64127 (NOD2)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
64127 (NOD2)
09160 Human Diseases
09171 Infectious disease: bacterial
05152 Tuberculosis
64127 (NOD2)
09163 Immune disease
05321 Inflammatory bowel disease
64127 (NOD2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:hsa04054]
64127 (NOD2)
Pattern recognition receptors [BR:hsa04054]
Cytoplasmic pattern recognition receptors
NOD-like receptors
64127 (NOD2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:50693606..50733075
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| AA seq |
1040 aa
MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWL
LSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLH
GCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQR
ARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTY
DGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGE
AGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQ
EDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNAR
KVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALH
GLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLL
RGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLE
FLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVA
ALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFH
SIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECA
ALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECAL
HCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTS
LQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEEL
CLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRG
NTFSLEEVDKLGCRDTRLLL |
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| NT seq |
3123 nt +upstreamnt +downstreamnt
atgggggaagagggtggttcagcctctcacgatgaggaggaaagagcaagtgtcctcctc
ggacattctccgggttgtgaaatgtgctcgcaggaggcttttcaggcacagaggagccag
ctggtcgagctgctggtctcagggtccctggaaggcttcgagagtgtcctggactggctg
ctgtcctgggaggtcctctcctgggaggactacgagggcttccacctcctgggccagcct
ctctcccacttggccaggcgccttctggacaccgtctggaataagggtacttgggcctgt
cagaagctcatcgcggctgcccaagaagcccaggccgacagccagtcccccaagctgcat
ggctgctgggacccccactcgctccacccagcccgagacctgcagagtcaccggccagcc
attgtcaggaggctccacagccatgtggagaacatgctggacctggcatgggagcggggt
ttcgtcagccagtatgaatgtgatgaaatcaggttgccgatcttcacaccgtcccagagg
gcaagaaggctgcttgatcttgccacggtgaaagcgaatggattggctgccttccttcta
caacatgttcaggaattaccagtcccattggccctgcctttggaagctgccacatgcaag
aagtatatggccaagctgaggaccacggtgtctgctcagtctcgcttcctcagtacctat
gatggagcagagacgctctgcctggaggacatatacacagagaatgtcctggaggtctgg
gcagatgtgggcatggctggacccccgcagaagagcccagccaccctgggcctggaggag
ctcttcagcacccctggccacctcaatgacgatgcggacactgtgctggtggtgggtgag
gcgggcagtggcaagagcacgctcctgcagcggctgcacttgctgtgggctgcagggcaa
gacttccaggaatttctctttgtcttcccattcagctgccggcagctgcagtgcatggcc
aaaccactctctgtgcggactctactctttgagcactgctgttggcctgatgttggtcaa
gaagacatcttccagttactccttgaccaccctgaccgtgtcctgttaacctttgatggc
tttgacgagttcaagttcaggttcacggatcgtgaacgccactgctccccgaccgacccc
acctctgtccagaccctgctcttcaaccttctgcagggcaacctgctgaagaatgcccgc
aaggtggtgaccagccgtccggccgctgtgtcggcgttcctcaggaagtacatccgcacc
gagttcaacctcaagggcttctctgaacagggcatcgagctgtacctgaggaagcgccat
catgagcccggggtggcggaccgcctcatccgcctgctccaagagacctcagccctgcac
ggtttgtgccacctgcctgtcttctcatggatggtgtccaaatgccaccaggaactgttg
ctgcaggagggggggtccccaaagaccactacagatatgtacctgctgattctgcagcat
tttctgctgcatgccacccccccagactcagcttcccaaggtctgggacccagtcttctt
cggggccgcctccccaccctcctgcacctgggcagactggctctgtggggcctgggcatg
tgctgctacgtgttctcagcccagcagctccaggcagcacaggtcagccctgatgacatt
tctcttggcttcctggtgcgtgccaaaggtgtcgtgccagggagtacggcgcccctggaa
ttccttcacatcactttccagtgcttctttgccgcgttctacctggcactcagtgctgat
gtgccaccagctttgctcagacacctcttcaattgtggcaggccaggcaactcaccaatg
gccaggctcctgcccacgatgtgcatccaggcctcggagggaaaggacagcagcgtggca
gctttgctgcagaaggccgagccgcacaaccttcagatcacagcagccttcctggcaggg
ctgttgtcccgggagcactggggcctgctggctgagtgccagacatctgagaaggccctg
ctccggcgccaggcctgtgcccgctggtgtctggcccgcagcctccgcaagcacttccac
tccatcccgccagctgcaccgggtgaggccaagagcgtgcatgccatgcccgggttcatc
tggctcatccggagcctgtacgagatgcaggaggagcggctggctcggaaggctgcacgt
ggcctgaatgttgggcacctcaagttgacattttgcagtgtgggccccactgagtgtgct
gccctggcctttgtgctgcagcacctccggcggcccgtggccctgcagctggactacaac
tctgtgggtgacattggcgtggagcagctgctgccttgccttggtgtctgcaaggctctg
tatttgcgcgataacaatatctcagaccgaggcatctgcaagctcattgaatgtgctctt
cactgcgagcaattgcagaagttagctctattcaacaacaaattgactgacggctgtgca
cactccatggctaagctccttgcatgcaggcagaacttcttggcattgaggctggggaat
aactacatcactgccgcgggagcccaagtgctggccgaggggctccgaggcaacacctcc
ttgcagttcctgggattctggggcaacagagtgggtgacgagggggcccaggccctggct
gaagccttgggtgatcaccagagcttgaggtggctcagcctggtggggaacaacattggc
agtgtgggtgcccaagccttggcactgatgctggcaaagaacgtcatgctagaagaactc
tgcctggaggagaaccatctccaggatgaaggtgtatgttctctcgcagaaggactgaag
aaaaattcaagtttgaaaatcctgaagttgtccaataactgcatcacctacctaggggca
gaagccctcctgcaggcccttgaaaggaatgacaccatcctggaagtctggctccgaggg
aacactttctctctagaggaggttgacaagctcggctgcagggacaccagactcttgctt
tga |
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