| Entry |
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| Symbol |
NOD2, CARD15
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| Name |
nucleotide-binding oligomerization domain-containing protein 2
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| Pathway |
| map04621 | NOD-like receptor signaling pathway |
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| Disease |
| H01227 | Inflammatory bowel disease (IBD) |
| H01309 | Sarcoidosis, early-onset |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
09160 Human Diseases
09171 Infectious disease: bacterial
05152 Tuberculosis
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
09163 Immune disease
05321 Inflammatory bowel disease
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
Pattern recognition receptors [BR:ko04054]
Cytoplasmic pattern recognition receptors
NOD-like receptors
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
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| Genes |
» show all
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| Reference |
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| Authors |
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M |
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| Title |
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. |
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| Journal |
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| Reference |
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| Authors |
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G |
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| Title |
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. |
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| Journal |
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| Sequence |
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| LinkDB |
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