Homo sapiens (human): 64283
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Entry
64283 CDS
T01001
Symbol
ARHGEF28, RGNEF, RIP2, p190RHOGEF
Name
(RefSeq) Rho guanine nucleotide exchange factor 28
KO
K21072
A-kinase anchor protein 28
Organism
hsa
Homo sapiens (human)
Pathway
hsa05135
Yersinia infection
Network
nt06181
Salmonella
nt06182
Shigella
nt06183
Yersinia
Element
N01072
ITGA/B-RhoGEF-RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09171 Infectious disease: bacterial
05135 Yersinia infection
64283 (ARHGEF28)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
64283 (ARHGEF28)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
64283 (ARHGEF28)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH_16
RhoGEF
C1_1
PH
PHD
C1_2
SOS1_NGEF_PH
Prok-RING_1
PH_13
Motif
Other DBs
NCBI-GeneID:
64283
NCBI-ProteinID:
NP_001171164
OMIM:
612790
HGNC:
30322
Ensembl:
ENSG00000214944
Pharos:
Q8N1W1
(Tbio)
UniProt:
Q8N1W1
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:73626196..73941990
Genome browser
AA seq
1705 aa
AA seq
DB search
MELSCSEAPLYGQMMIYAKFDKNVYLPEDAEFYFTYDGSHQRHVMIAERIEDNVLQSSVP
GHGLQETVTVSVCLCSEGYSPVTMGSGSVTYVDNMACRLARLLVTQANRLTACSHQTLLT
PFALTAGALPALDEELVLALTHLELPLEWTVLGSSSLEVSSHRESLLHLAMRWGLAKLSQ
FFLCLPGGVQALALPNEEGATPLDLALREGHSKLVEDVTNFQGRWSPSFSRVQLSEEASL
HYIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDRAFLVKAFEPEARPEERTAMPSSGAE
TEEEIKNSVSSRSAAEKEDIKRVKSLVVQHNEHEDQHSLDLDRSFDILKKSKPPSTLLAA
GRLSDMLNGGDEVYANCMVIDQVGDLDISYINIEGITATTSPESRGCTLWPQSSKHTLPT
ETSPSVYPLSENVEGTAHTEAQQSFMSPSSSCASNLNLSFGWHGFEKEQSHLKKRSSSLD
ALDADSEGEGHSEPSHICYTPGSQSSSRTGIPSGDELDSFETNTEPDFNISRAESLPLSS
NLQSKESLLSGVRSRSYSCSSPKISLGKTRLVRELTVCSSSEEQRAYSLSEPPRENRIQE
EEWDKYIIPAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKSKDAKDKEKLNRHQFAPGTF
SGVLQCLVCDKTLLGKESLQCSNCNANVHKGCKDAAPACTKKFQEKYNKNKPQTILGNSS
FRDIPQPGLSLHPSSSVPVGLPTGRRETVGQVHPLSRSVPGTTLESFRRSATSLESESDH
NSCRSRSHSDELLQSMGSSPSTESFIMEDVVDSSLWSDLSSDAQEFEAESWSLVVDPSFC
NRQEKDVIKRQDVIFELMQTEMHHIQTLFIMSEIFRKGMKEELQLDHSTVDKIFPCLDEL
LEIHRHFFYSMKERRQESCAGSDRNFVIDRIGDILVQQFSEENASKMKKIYGEFCCHHKE
AVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKER
TEEHKDLRKALCLIKDMIATVDLKVNEYEKNQKWLEILNKIENKTYTKLKNGHVFRKQAL
MSEERTLLYDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQK
LIAREVANEERGMFLISASSAGPEMYEIHTNSKEERNNWMRRIQQAVESCPEEKGGRTSE
SDEDKRKAEARVAKIQQCQEILTNQDQQICAYLEEKLHIYAELGELSGFEDVHLEPHLLI
KPDPGEPPQAASLLAAALKEAESLQVAVKASQMGAVSQSCEDSCGDSVLADTLSSHDVPG
SPTASLVTGGREGRGCSDVDPGIQGVVTDLAVSDAGEKVECRNFPGSSQSEIIQAIQNLT
RLLYSLQAALTIQDSHIEIHRLVLQQQEGLSLGHSILRGGPLQDQKSRDADRQHEELANV
HQLQHQLQQEQRRWLRRCEQQQRAQATRESWLQERERECQSQEELLLRSRGELDLQLQEY
QHSLERLREGQRLVEREQARMRAQQSLLGHWKHGRQRSLPAVLLPGGPEVMELNRSESLC
HENSFFINEALVQMSFNTFNKLNPSVIHQDATYPTTQSHSDLVRTSEHQVDLKVDPSQPS
NVSHKLWTAAGSGHQILPFHESSKDSCKNDLDTSHTESPTPHDSNSHRPQLQAFITEAKL
NLPTRTMTRQDGETGDGAKENIVYL
NT seq
5118 nt
NT seq
+upstream
nt +downstream
nt
atggagttgagctgcagcgaagcacctctttacgggcagatgatgatctatgcgaagttt
gacaaaaatgtgtatcttcctgaagatgctgagttttactttacttatgacggatctcat
cagcgacatgtcatgattgcagagcgcatcgaggataacgttctccagtccagcgtccca
ggccatgggcttcaggagacggtgacggtatctgtgtgcctctgctcggaaggttactct
ccggtgaccatgggctctggctcagtgacctacgtggacaacatggcttgcaggctggct
cgtctgctggtgacgcaggccaatcgcctcacagcctgcagccaccagaccctgctgacc
ccatttgccttgacggcaggagcactgcctgccttggatgaggagctcgtgctggctctg
acccatctggaattgcctctagagtggactgtgttgggaagttcttcacttgaagtatct
tctcacagagaatctcttctacacctggctatgagatggggcctggctaaactttcccag
ttcttcttgtgtctcccggggggagtccaggccttggctttacccaacgaagagggtgcc
acaccattagacttagctttacgtgaaggacactccaagctggtggaagacgtcacaaat
tttcagggcagatggtccccaagcttctcccgagtgcagctcagtgaagaagcctccttg
cattacattcactcatcggaaacgctgaccctgaccctgaaccacacagccgagcatttg
ttggaggcagatattaaactcttccggaaatacttttgggatagagcctttcttgtcaag
gcctttgagccagaagccaggccagaggaaagaacagctatgccctccagcggtgcagaa
actgaagaagagattaagaattcagtgtccagcagatcagcagctgaaaaggaagatata
aagcgtgtcaaaagcctggtggttcaacacaatgaacatgaagaccagcacagcctagat
ttggatcgctccttcgatatcctaaaaaaatccaagccgccctcgacattgcttgctgca
ggccggctttcagacatgctgaatggaggtgatgaagtctacgctaactgtatggtgatt
gatcaggttggtgatttggatatcagctatattaatatagagggaatcactgccactacc
agccctgaatccagaggttgcactctgtggcctcagagcagcaaacacacccttcctaca
gaaaccagtcccagtgtgtacccacttagtgaaaatgtcgaagggacagcacacactgaa
gcccagcagtccttcatgtcaccatcaagttcgtgtgcttccaacttgaatctttctttt
ggttggcatggatttgaaaaggaacaaagtcatctaaagaaaagaagttctagccttgat
gccttggacgccgacagtgaaggggaagggcattctgagccatcccacatctgttacact
ccagggtctcagagctcctcaagaactgggattcctagtggggatgaattggactctttt
gagactaacactgaaccggattttaatatctccagggctgaatcccttcctctatcaagt
aatctacagtcgaaggaatcactgctttctggagttcgctcacgttcttattcttgctca
tcacccaaaatttctttaggaaaaactcgtttggtgcgtgaattaacagtatgcagttca
agtgaagagcaaagagcttacagcttatcggagccaccaagagaaaacagaattcaggaa
gaagaatgggataaatacatcatacctgccaaatcagagtctgaaaaatataaagtgagt
cgaactttcagtttcctcatgaataggatgactagccctcggaataaatcaaagacaaaa
agcaaggatgccaaagataaagagaagctgaatcgacatcagtttgccccaggaacattc
tctggggttctgcagtgtttggtttgtgataaaacactcctggggaaagagtcactgcag
tgttctaactgtaatgcaaatgtgcacaaaggttgtaaagatgctgcgcctgcatgcacc
aagaaattccaagagaaatataacaagaacaaaccacagaccatccttggaaattcttca
tttagagacatcccacagcctggtctctccttgcacccttcttcctccgtgcctgttgga
ttgccgactggaaggagggagactgtgggacaggtccatccattgtccagaagtgttcca
ggcaccaccttggaaagcttcaggaggtcagccacatccttggagtctgagagtgaccat
aacagctgcagaagcaggtctcattctgatgagctgctacagtccatgggctcttctccc
tctacagagtctttcataatggaagatgttgtggattcttctctgtggagtgacctcagc
agtgatgcccaggagtttgaagcagaatcttggagtcttgtggtggatccctcattttgt
aataggcaggagaaggatgtcatcaaaagacaggatgtcatttttgagctaatgcaaaca
gagatgcatcacatccagaccctgttcatcatgtctgagatcttcaggaaaggcatgaaa
gaggagctgcagctggaccacagcaccgtggataaaattttcccctgtttagatgagttg
cttgaaatccacaggcatttcttctacagtatgaaggaacgaaggcaggaatcctgtgct
ggcagcgacaggaattttgtgatcgaccgaattggagatattttggtacaacagttttca
gaagaaaatgcaagtaaaatgaagaaaatatatggagaattctgttgccatcataaagaa
gctgttaacctctttaaagaactccagcagaataaaaagtttcagaattttattaagctc
cgaaatagtaatcttttggctcgacgccgaggaattccagaatgcattctgttggtcact
cagcgtattacaaaataccctgtcttggtggaaaggatattgcagtacacaaaggaaaga
actgaggaacataaagacttacgcaaagcgctttgcttaattaaagacatgattgcaaca
gtggatttaaaagtcaatgaatatgagaaaaaccaaaaatggcttgagatcctaaataag
attgaaaacaaaacatacacgaagctcaaaaatggacatgtgtttaggaagcaggcactg
atgagtgaagaaaggactctgttatatgatggccttgtttactggaaaactgctacaggt
cgtttcaaagatatcctagctctacttctaactgatgtgctgctctttttacaagaaaaa
gaccagaaatacatctttgcagccgttgatcagaagccatcagttatttcccttcaaaag
cttattgctagagaagttgctaatgaggagagaggaatgtttctgatcagtgcttcatct
gctggtcctgagatgtatgaaattcacaccaattccaaggaggaacgcaataactggatg
agacggatccagcaggctgtagaaagttgtcctgaagaaaaagggggaaggacaagtgaa
tctgatgaagacaagaggaaagctgaagccagagtggccaaaattcagcaatgtcaagaa
atactcactaaccaagaccaacaaatttgtgcgtatttggaggagaagctgcatatctat
gctgaacttggagaactgagcggatttgaggacgtccatctagagccccacctccttatt
aaacctgacccaggcgagcctccccaggcagcctcattactggcagcagcactgaaagaa
gctgagagcctacaagttgcagtgaaggcctcacagatgggcgccgtgagtcaatcatgt
gaggacagttgtggagactctgtcttggcggacacactcagttctcatgatgtaccagga
tcaccgactgcctcattagtcacaggagggagagaaggaagaggctgttcggatgtggat
cccgggatccagggtgtggtaaccgacttggccgtctctgatgcaggggagaaggtggaa
tgtagaaattttccaggttcttcacaatcagagattatacaagccatacagaatttaacc
cgtctcttatacagccttcaggccgccttgaccattcaggacagccacattgagatccac
aggctggttctccagcagcaggagggcctgtctctcggccactctatcctccgaggcggc
cccttgcaggaccagaagtctcgcgacgcggacaggcagcatgaggagctggccaatgtg
caccagcttcagcaccagctccagcaggagcagcggcgctggctgcgcaggtgtgagcag
cagcagcgggcgcaggcgaccagggagagctggctgcaggagcgggagcgggagtgccag
tcgcaggaggagctgctgctgcggagccggggcgagctggacctccagctccaggagtac
cagcacagcctggagcggctgagggagggccagcgcctggtggagagggagcaggcgagg
atgcgggcccagcagagcctgctgggccactggaagcacggccggcagaggagcctgccc
gcggtgctccttccgggtggccccgaggtaatggaacttaatcgatctgagagtttatgt
catgaaaactcattcttcatcaatgaagctttagtacaaatgtcatttaacactttcaac
aaactgaatccatcagttatccatcaggatgccacttaccctacaactcaatctcattct
gacttggtgaggactagtgaacatcaagtagacctcaaggtggacccttctcagccttcg
aatgtcagtcacaaactgtggacagccgctggttccggccatcagatacttcctttccat
gaaagcagcaaggattcttgtaaaaatgatttggacacctcccacactgagtccccaacc
ccccatgactcaaattcacaccgccctcaactgcaggcgtttataacagaagcaaagcta
aatctaccgacaaggacaatgaccagacaagatggggaaactggagatggagccaaagaa
aatattgtttacctctaa
DBGET
integrated database retrieval system
