Homo sapiens (human): 6464 Help Entry 6464              CDS       T01001                                  Symbol SHC1, SHC, SHCA Name (RefSeq) SHC adaptor protein 1   KO K06279   SHC-transforming protein 1 Organism hsa  Homo sapiens (human) Pathway hsa01521   EGFR tyrosine kinase inhibitor resistance hsa01522   Endocrine resistance hsa04012   ErbB signaling pathway hsa04014   Ras signaling pathway hsa04062   Chemokine signaling pathway hsa04072   Phospholipase D signaling pathway hsa04510   Focal adhesion hsa04650   Natural killer cell mediated cytotoxicity hsa04722   Neurotrophin signaling pathway hsa04910   Insulin signaling pathway hsa04915   Estrogen signaling pathway hsa04917   Prolactin signaling pathway hsa04926   Relaxin signaling pathway hsa04935   Growth hormone synthesis, secretion and action hsa05034   Alcoholism hsa05100   Bacterial invasion of epithelial cells hsa05206   MicroRNAs in cancer hsa05214   Glioma hsa05220   Chronic myeloid leukemia hsa05224   Breast cancer hsa05225   Hepatocellular carcinoma hsa05226   Gastric cancer Network nt06526  MAPK signaling nt06543  NRG-ERBB signaling   Element N01595   Regulation of GF-RTK-RAS-ERK signaling pathway, adaptor proteins N01874   NRG-ERBB2/ERBB3 pathway (RAS-ERK signaling) Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     6464 (SHC1)    04072 Phospholipase D signaling pathway     6464 (SHC1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     6464 (SHC1)    04062 Chemokine signaling pathway     6464 (SHC1)   09152 Endocrine system    04915 Estrogen signaling pathway     6464 (SHC1)    04917 Prolactin signaling pathway     6464 (SHC1)    04926 Relaxin signaling pathway     6464 (SHC1)    04935 Growth hormone synthesis, secretion and action     6464 (SHC1)   09156 Nervous system    04722 Neurotrophin signaling pathway     6464 (SHC1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     6464 (SHC1)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     6464 (SHC1)    05226 Gastric cancer     6464 (SHC1)    05214 Glioma     6464 (SHC1)    05220 Chronic myeloid leukemia     6464 (SHC1)    05224 Breast cancer     6464 (SHC1)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     6464 (SHC1)   09165 Substance dependence    05034 Alcoholism     6464 (SHC1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     6464 (SHC1)    01522 Endocrine resistance     6464 (SHC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PID SH2 DUF7063 Delta_lysin DUF7461 Motif Other DBs NCBI-GeneID:  6464 NCBI-ProteinID:  NP_892113 OMIM:  600560 HGNC:  10840 Ensembl:  ENSG00000160691 UniProt:  P29353 Structure PDBPDBj LinkDB All DBs Position 1:complement(154962298..154974376) Genome browser AA seq 583 aa AA seqDB search MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRE LFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMA EQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEG VVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL NT seq 1752 nt NT seq  +upstreamnt  +downstreamnt atggatctcctgccccccaagcccaagtacaatccactccggaatgagtctctgtcatcg ctggaggaaggggcttctgggtccacccccccggaggagctgccttccccatcagcttca tccctggggcccatcctgcctcctctgcctggggacgatagtcccactaccctgtgctcc ttcttcccccggatgagcaacctgaggctggccaacccggctggggggcgcccagggtct aagggggagccaggaagggcagctgatgatggggaggggatcgtaggggcagccatgcca gactcaggccccctacccctcctccaggacatgaacaagctgagtggaggcggcgggcgc aggactcgggtggaagggggccagcttgggggcgaggagtggacccgccacgggagcttt gtcaataagcccacgcggggctggctgcatcccaacgacaaagtcatgggacccggggtt tcctacttggttcggtacatgggttgtgtggaggtcctccagtcaatgcgtgccctggac ttcaacacccggactcaggtcaccagggaggccatcagtctggtgtgtgaggctgtgccg ggtgctaagggggcgacaaggaggagaaagccctgtagccgcccgctcagctctatcctg gggaggagtaacctgaaatttgctggaatgccaatcactctcaccgtctccaccagcagc ctcaacctcatggccgcagactgcaaacagatcatcgccaaccaccacatgcaatctatc tcatttgcatccggcggggatccggacacagccgagtatgtcgcctatgttgccaaagac cctgtgaatcagagagcctgccacattctggagtgtcccgaagggcttgcccaggatgtc atcagcaccattggccaggccttcgagttgcgcttcaaacaatacctcaggaacccaccc aaactggtcacccctcatgacaggatggctggctttgatggctcagcatgggatgaggag gaggaagagccacctgaccatcagtactataatgacttcccggggaaggaaccccccttg gggggggtggtagacatgaggcttcgggaaggagccgctccaggggctgctcgacccact gcacccaatgcccagacccccagccacttgggagctacattgcctgtaggacagcctgtt gggggagatccagaagtccgcaaacagatgccacctccaccaccctgtccaggcagagag ctttttgatgatccctcctatgtcaacgtccagaacctagacaaggcccggcaagcagtg ggtggtgctgggccccccaatcctgctatcaatggcagtgcaccccgggacctgtttgac atgaagcccttcgaagatgctcttcgcgtgcctccacctccccagtcggtgtccatggct gagcagctccgaggggagccctggttccatgggaagctgagccggcgggaggctgaggca ctgctgcagctcaatggggacttcctggtacgggagagcacgaccacacctggccagtat gtgctcactggcttgcagagtgggcagcctaagcatttgctactggtggaccctgagggt gtggttcggactaaggatcaccgctttgaaagtgtcagtcaccttatcagctaccacatg gacaatcacttgcccatcatctctgcgggcagcgaactgtgtctacagcaacctgtggag cggaaactgtga

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