Homo sapiens (human): 6507
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Entry
6507 CDS
T01001
Symbol
SLC1A3, EA6, EAAT1, GLAST, GLAST1
Name
(RefSeq) solute carrier family 1 member 3
KO
K05614
solute carrier family 1 (glial high affinity glutamate transporter), member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04082
Neuroactive ligand signaling
hsa04721
Synaptic vesicle cycle
hsa04724
Glutamatergic synapse
hsa05016
Huntington disease
Network
nt06544
Neuroactive ligand signaling
Element
N01884
Transport of glutamate, EAAT
Disease
H00749
Episodic ataxias
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
6507 (SLC1A3)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
6507 (SLC1A3)
04721 Synaptic vesicle cycle
6507 (SLC1A3)
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
6507 (SLC1A3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6507 (SLC1A3)
04147 Exosome [BR:
hsa04147
]
6507 (SLC1A3)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC1: High-affinity glutamate and neutral amino acid transporter
6507 (SLC1A3)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of cortical neuronal cells
6507 (SLC1A3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SDF
MT
Motif
Other DBs
NCBI-GeneID:
6507
NCBI-ProteinID:
NP_004163
OMIM:
600111
HGNC:
10941
Ensembl:
ENSG00000079215
UniProt:
P43003
Q8N169
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:36606606..36688334
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AA seq
542 aa
AA seq
DB search
MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
KM
NT seq
1629 nt
NT seq
+upstream
nt +downstream
nt
atgactaaaagcaatggagaagagcccaagatggggggcaggatggagagattccagcag
ggagtccgtaaacgcacacttttggccaagaagaaagtgcagaacattacaaaggaggat
gttaaaagttacctgtttcggaatgcttttgtgctgctcacagtcaccgctgtcattgtg
ggtacaatccttggatttaccctccgaccatacagaatgagctaccgggaagtcaagtac
ttctcctttcctggggaacttctgatgaggatgttacagatgctggtcttaccacttatc
atctccagtcttgtcacaggaatggcggcgctagatagtaaggcatcagggaagatggga
atgcgagctgtagtctattatatgactaccaccatcattgctgtggtgattggcataatc
attgtcatcatcatccatcctgggaagggcacaaaggaaaacatgcacagagaaggcaaa
attgtacgagtgacagctgcagatgccttcctggacttgatcaggaacatgttccctcca
aatctggtagaagcctgctttaaacagtttaaaaccaactatgagaagagaagctttaaa
gtgcccatccaggccaacgaaacgcttgtgggtgctgtgataaacaatgtgtctgaggcc
atggagactcttacccgaatcacagaggagctggtcccagttccaggatctgtgaatgga
gtcaatgccctgggtctagttgtcttctccatgtgcttcggttttgtgattggaaacatg
aaggaacaggggcaggccctgagagagttctttgattctcttaacgaagccatcatgaga
ctggtagcagtaataatgtggtatgcccccgtgggtattctcttcctgattgctgggaag
attgtggagatggaagacatgggtgtgattggggggcagcttgccatgtacaccgtgact
gtcattgttggcttactcattcacgcagtcatcgtcttgccactcctctacttcttggta
acacggaaaaacccttgggtttttattggagggttgctgcaagcactcatcaccgctctg
gggacctcttcaagttctgccaccctacccatcaccttcaagtgcctggaagagaacaat
ggcgtggacaagcgcgtcaccagattcgtgctccccgtaggagccaccattaacatggat
gggactgccctctatgaggctttggctgccattttcattgctcaagttaacaactttgaa
ctgaacttcggacaaattattacaatcagcatcacagccacagctgccagtattggggca
gctggaattcctcaggcgggcctggtcactatggtcattgtgctgacatctgtcggcctg
cccactgacgacatcacgctcatcatcgcggtggactggttcctggatcgcctccggacc
accaccaacgtactgggagactccctgggagctgggattgtggagcacttgtcacgacat
gaactgaagaacagagatgttgaaatgggtaactcagtgattgaagagaatgaaatgaag
aaaccatatcaactgattgcacaggacaatgaaactgagaaacccatcgacagtgaaacc
aagatgtag
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