Homo sapiens (human): 65263
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Entry
65263 CDS
T01001
Symbol
PYCR3, PYCRL
Name
(RefSeq) pyrroline-5-carboxylate reductase 3
KO
K00286
pyrroline-5-carboxylate reductase [EC:
1.5.1.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00330
Arginine and proline metabolism
hsa01100
Metabolic pathways
hsa01230
Biosynthesis of amino acids
Module
hsa_M00015
Proline biosynthesis, glutamate => proline
hsa_M00972
Proline metabolism
Network
nt06033
Glycine, serine and arginine metabolism
Element
N01618
Proline biosynthesis, Orn to Pro
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00330 Arginine and proline metabolism
65263 (PYCR3)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.2 pyrroline-5-carboxylate reductase
65263 (PYCR3)
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Gene cluster
GFIT
Motif
Pfam:
P5CR_dimer
F420_oxidored
Rossmann-like
DapB_N
NAD_Gly3P_dh_N
NAD_binding_2
zf-TRAF
ApbA
PDH_N
Motif
Other DBs
NCBI-GeneID:
65263
NCBI-ProteinID:
NP_075566
OMIM:
616408
HGNC:
25846
Ensembl:
ENSG00000104524
UniProt:
Q53H96
A0A0A0MQS1
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Position
8:complement(143603210..143609575)
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AA seq
274 aa
AA seq
DB search
MAAAEPSPRRVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQALGCRTTH
SNQEVLQSCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLPPNTRV
LRVLPNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSG
VAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGT
TIYGLHALEQGGLRAATMSAVEAATCRAKELSRK
NT seq
825 nt
NT seq
+upstream
nt +downstream
nt
atggcagctgcggagccgtctccgcggcgcgtgggcttcgtgggcgcgggccgcatggcg
ggggccatcgcgcagggcctcatcagagcaggaaaagtggaagctcagcacatactggcc
agtgcaccaacagacaggaacctatgtcactttcaagctctgggttgccggaccacgcac
tccaaccaggaggtgctgcagagctgcctgctcgtcatctttgccaccaagcctcatgtg
ctgccagctgtcctggcagaggtggctcctgtggtcaccactgaacacatcttggtgtcc
gtggctgctggggtgtctctgagcaccctggaggagctgctgcccccaaacacacgggtg
ctgcgggtcttgcccaacctgccctgtgtggtccaggaaggggccatagtgatggcgcgg
ggccgccacgtggggagcagcgagaccaagctcctgcagcatctgctggaggcctgtggg
cggtgtgaggaggtgcctgaagcctacgtcgacatccacactggcctcagtggcagtggc
gtggccttcgtgtgtgcattctccgaggccctggctgaaggagccgtcaagatgggcatg
cccagcagcctggcccaccgcatcgctgcccagaccctgctggggacggccaagatgctg
ctgcacgagggccaacacccagcccagctgcgctcagacgtgtgcaccccgggtggcacc
accatctatggactccacgccctggagcagggcgggctgcgagcagccaccatgagcgcc
gtggaggctgccacctgccgggccaaggagctcagcagaaagtag
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