| Entry |
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| Symbol |
NCF1, CGD1, NCF-1, NCF-47K, NCF1A, NOXO2, SH3PXD1A, p47-phox, p47phox
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| Name |
(RefSeq) neutrophil cytosolic factor 1
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| KO |
| K08011 | neutrophil cytosolic factor 1 |
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| Organism |
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| Pathway |
| hsa04613 | Neutrophil extracellular trap formation |
| hsa04666 | Fc gamma R-mediated phagocytosis |
| hsa04670 | Leukocyte transendothelial migration |
| hsa05208 | Chemical carcinogenesis - reactive oxygen species |
| hsa05418 | Fluid shear stress and atherosclerosis |
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| Network |
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| Element |
| N01204 | PRNP-PI3K-NOX2 signaling pathway |
| N01205 | Scrapie conformation PrPSc to PRNP-PI3K-NOX2 signaling pathway |
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| Disease |
| H00098 | Chronic granulomatous disease |
| H01167 | Granulibacter infection |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
653361 (NCF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
653361 (NCF1)
04666 Fc gamma R-mediated phagocytosis
653361 (NCF1)
04670 Leukocyte transendothelial migration
653361 (NCF1)
04062 Chemokine signaling pathway
653361 (NCF1)
09158 Development and regeneration
04380 Osteoclast differentiation
653361 (NCF1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
653361 (NCF1)
09174 Infectious disease: parasitic
05140 Leishmaniasis
653361 (NCF1)
09164 Neurodegenerative disease
05020 Prion disease
653361 (NCF1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
653361 (NCF1)
05418 Fluid shear stress and atherosclerosis
653361 (NCF1)
05415 Diabetic cardiomyopathy
653361 (NCF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
653361 (NCF1)
Membrane trafficking [BR:hsa04131]
Others
NADPH oxidases (Nox) and associated proteins
Nox associated proteins
653361 (NCF1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
7:74774011..74789315
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| AA seq |
390 aa
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV |
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| NT seq |
1173 nt +upstreamnt +downstreamnt
atgggggacaccttcatccgtcacatcgccctgctgggctttgagaagcgcttcgtaccc
agccagcactatgtgtacatgttcctggtgaaatggcaggacctgtcggagaaggtggtc
taccggcgcttcaccgagatctacgagttccataaaaccttaaaagaaatgttccctatt
gaggcaggggcgatcaatccagagaacaggatcatcccccacctcccagctcccaagtgg
tttgacgggcagcgggccgccgagaaccgccagggcacacttaccgagtactgcagcacg
ctcatgagcctgcccaccaagatctcccgctgtccccacctcctcgacttcttcaaggtg
cgccctgatgacctcaagctccccacggacaaccagacaaaaaagccagagacatacttg
atgcccaaagatggcaagagtaccgcgacagacatcaccggccccatcatcctgcagacg
taccgcgccattgccaactacgagaagacctcgggctccgagatggctctgtccacgggg
gacgtggtggaggtcgtagagaagagcgagagcggttggtggttctgtcagatgaaagca
aagcgaggctggatcccagcgtccttcctcgagcccctggacagtcctgacgagacggaa
gaccctgagcccaactatgcaggtgagccatacgtcgccatcaaggcctacactgctgtg
gagggggacgaggtgtccctgctcgagggtgaagctgttgaggtcattcacaagctcctg
gacggctggtgggtcatcaggaaagacgacgtcacaggctacttcccgtccatgtacctg
caaaagtcagggcaagacgtgtcccaggcccaacgccagatcaagcggggggcgccgccc
cgcaggtcgtccatccgcaacgcgcacagcatccaccagcggtcgcggaagcgcctcagc
caggacgcctatcgccgcaacagcgtccgttttctgcagcagcgacgccgccaggcgcgg
ccgggaccgcagagccccgggagcccgctcgaggaggagcggcagacgcagcgctctaaa
ccgcagccggcggtgcccccgcggccgagcgccgacctcatcctgaaccgctgcagcgag
agcaccaagcggaagctggcgtctgccgtctga |
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