Homo sapiens (human): 6580
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Entry
6580 CDS
T01001
Symbol
SLC22A1, HOCT1, OCT1, oct1_cds
Name
(RefSeq) solute carrier family 22 member 1
KO
K08198
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04976
Bile secretion
hsa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
6580 (SLC22A1)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
6580 (SLC22A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6580 (SLC22A1)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC22: Organic cation/anion/zwitterion transporter
6580 (SLC22A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Organic cation transporter (OCT) family [TC:
2.A.1.19
]
6580 (SLC22A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sugar_tr
MFS_1
Motif
Other DBs
NCBI-GeneID:
6580
NCBI-ProteinID:
NP_003048
OMIM:
602607
HGNC:
10963
Ensembl:
ENSG00000175003
UniProt:
O15245
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:160121815..160158718
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AA seq
554 aa
AA seq
DB search
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgcccaccgtggatgacattctggagcaggttggggagtctggctggttccagaagcaa
gccttcctcatcttatgcctgctgtcggctgcctttgcgcccatctgtgtgggcatcgtc
ttcctgggtttcacacctgaccaccactgccagagtcctggggtggctgagctgagccag
cgctgtggctggagccctgcggaggagctgaactatacagtgccaggcctggggcccgcg
ggcgaggccttccttggccagtgcaggcgctatgaagtggactggaaccagagcgccctc
agctgtgtagaccccctggctagcctggccaccaacaggagccacctgccgctgggtccc
tgccaggatggctgggtgtatgacacgcccggctcttccatcgtcactgagttcaacctg
gtgtgtgctgactcctggaagctggacctctttcagtcctgtttgaatgcgggcttcttg
tttggctctctcggtgttggctactttgcagacaggtttggccgtaagctgtgtctcctg
ggaactgtgctggtcaacgcggtgtcgggcgtgctcatggccttctcgcccaactacatg
tccatgctgctcttccgcctgctgcagggcctggtcagcaagggcaactggatggctggc
tacaccctaatcacagaatttgttggctcgggctccagaagaacggtggcgatcatgtac
cagatggccttcacggtggggctggtggcgcttaccgggctggcctacgccctgcctcac
tggcgctggctgcagctggcagtctccctgcccaccttcctcttcctgctctactactgg
tgtgtgccggagtcccctcggtggctgttatcacaaaaaagaaacactgaagcaataaag
ataatggaccacatcgctcaaaagaatgggaagttgcctcctgctgatttaaagatgctt
tccctcgaagaggatgtcaccgaaaagctgagcccttcatttgcagacctgttccgcacg
ccgcgcctgaggaagcgcaccttcatcctgatgtacctgtggttcacggactctgtgctc
tatcaggggctcatcctgcacatgggcgccaccagcgggaacctctacctggatttcctt
tactccgctctggtcgaaatcccgggggccttcatagccctcatcaccattgaccgcgtg
ggccgcatctaccccatggccatgtcaaatttgttggcgggggcagcctgcctcgtcatg
atttttatctcacctgacctgcactggttaaacatcataatcatgtgtgttggccgaatg
ggaatcaccattgcaatacaaatgatctgcctggtgaatgctgagctgtaccccacattc
gtcaggaacctcggagtgatggtgtgttcctccctgtgtgacataggtgggataatcacc
cccttcatagtcttcaggctgagggaggtctggcaagccttgcccctcattttgtttgcg
gtgttgggcctgcttgccgcgggagtgacgctacttcttccagagaccaagggggtcgct
ttgccagagaccatgaaggacgccgagaaccttgggagaaaagcaaagcccaaagaaaac
acgatttaccttaaggtccaaacctcagaaccctcgggcacctga
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