KEGG ORTHOLOGY: K08198

ORTHOLOGY: K08198

Entry

K08198                      KO

Symbol

SLC22A1, OCT1

Name

MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1

Pathway

map04976

Bile secretion

map05231

Choline metabolism in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1

Other DBs

GO:

0015101

TC:	2.A.1.19.1

Genes

HSA:	6580(SLC22A1)

PTR:	472177(SLC22A1)

PPS:	100993403(SLC22A1)

GGO:	101147842(SLC22A1)

PON:	100436901(SLC22A1)

PPYG:

129037994(SLC22A1)

NLE:	100587868(SLC22A1)

HMH:	116476279(SLC22A1)

SSYN:

129476128(SLC22A1)

MCC:	703449(SLC22A1)

MCF:	102116123(SLC22A1)

MTHB:

126953657

MNI:	105492009(SLC22A1)

CSAB:

103240834(SLC22A1)

CATY:

105581317(SLC22A1)

PANU:

101004311(SLC22A1)

TGE:	112622948(SLC22A1)

MLEU:

105536530(SLC22A1)

RRO:	104666418(SLC22A1)

RBB:	108516182(SLC22A1)

TFN:	117096921(SLC22A1)

PTEH:

111547274(SLC22A1)

CANG:

105506729(SLC22A1)

CJC:	100412933(SLC22A1)

SBQ:	101027460(SLC22A1)

CIMI:

108310872(SLC22A1)

ANAN:

105716517(SLC22A1)

CSYR:

103270360(SLC22A1)

MMUR:

105868589(SLC22A1)

LCAT:

123633434(SLC22A1)

ERUF:

138395048(SLC22A1)

PCOQ:

105812405(SLC22A1)

OGA:	100966262(SLC22A1)

MMU:	20517(Slc22a1)

MCAL:

110283911

MPAH:

110338308(Slc22a1)

RNO:	24904(Slc22a1)

MCOC:

116077500(Slc22a1)

ANU:

117700224

ASYL:

127673924

MUN:	110554860(Slc22a1)

CGE:	100763203(Slc22a1)

MAUA:

101834781

PROB:

127237716(Slc22a1)

PLEU:

114691368(Slc22a1)

PMAV:

102908764(Slc22a1)

MORG:

121466473(Slc22a1)

MFOT:

126497716

AAMP:

119821204(Slc22a1)

CNL:

130870025

NGI:	103734803(Slc22a1)

HGL:	101706844(Slc22a1)

CPOC:

100736189

CCAN:

109682989(Slc22a1)

DORD:

105991844(Slc22a1)

DSP:

122116127

DMER:

138819066(Slc22a1)

PLOP:

125357466

NCAR:

124989130 124989762

MMMA:

107153111

ITI:	101965804(Slc22a1)

OCU:	100008659(SLC22A1)

OPI:	101516946(SLC22A1)

OCZ:	121146135(SLC22A1)

GVR:

103610494

CFA:	484068(SLC22A1)

CLUD:

112644395(SLC22A1)

VVP:

112935152

VLG:	121484507(SLC22A1)

NPO:	129500434(SLC22A1)

AML:	100476497(SLC22A1)

UMR:	103660829(SLC22A1)

UAH:

UAR:

ELK:

LLV:

MPUF:

101674581(SLC22A1)

MNP:

132018442

MLK:

131833397

NVS:	122902798(SLC22A1)

ORO:	101381071(SLC22A1)

EJU:

114209326

ZCA:

113927692

MLX:	118001815 118001938

NSU:

110583361

LWW:	102741670(SLC22A1)

FCA:	101094761(SLC22A1)

PYU:

121013218

PCOO:

112862217

PBG:	122490153(SLC22A1)

PVIV:

125165398(SLC22A1)

LRUF:

124528801

LGF:	123609257(SLC22A1)

AJU:

106989429

PTG:	102952142(SLC22A1)

PPAD:

109245396(SLC22A1)

PUC:

125939031

PLEZ:

122220566(SLC22A1)

HHV:

120223339

BTA:	519461(SLC22A1)

BOM:

BIU:

BBUB:

BKE:

BBIS:

104989261(SLC22A1)

CHX:

102183874

OAS:	101112740(SLC22A1)

BTAX:

128053433(SLC22A1)

CSUM:

138089829

ODA:	120862819(SLC22A1)

CCAD:

122434173(SLC22A1)

MREE:

136165102(SLC22A1)

OVR:

110126713

MBEZ:

129561090

SSC:	397049(SLC22A1)

CFR:	102510283(SLC22A1)

CBAI:

105077370(SLC22A1)

CDK:	105100382(SLC22A1)

VPC:

102525726

BACU:

103008472(SLC22A1)

BMUS:

118905254

LVE:	103076375(SLC22A1)

OOR:

LALB:

GMF:

DDP:

DLE:	111167637(SLC22A1)

PCAD:

102980252

PSIU:

116763761

PPHC:

136131757

NASI:

112401588(SLC22A1)

ECB:	100058455(SLC22A1)

EPZ:

103558447

EAI:	106842042(SLC22A1)

MMF:	118621674(SLC22A1)

HAI:	109394003(SLC22A1)

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:	108409364(SLC22A1)

TOD:	119253501(SLC22A1)

SARA:

101558390

SFUM:

130034641

SETR:

125996531

LAV:	100656903(SLC22A1)

TMU:

101343732

ETF:

101641191

DNM:	101439072(SLC22A1)

MDO:	100027984(SLC22A1)

GAS:

SHR:

AFZ:

PCW:

TVP:

PBRV:

MLAO:

TACU:

CLEP:

ATD:

NVL:

BMOR:

BPHI:

ONU:

ATRA:

PXY:

LGLY:

CSTB:

CFUM:

BROR:

ESN:

MNZ:	135203571 135203760 135217476 135217753

MRJ:	136835013 136835145 136835607

LSM:	121114115 121116100

TCF:

DALB:

RSAN:

DFR:

CVS:

OVI:	T265_09072

» show all

Reference

PMID:9187257

Authors

Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM

Title

Cloning and functional expression of a human liver organic cation transporter.

Journal

Mol Pharmacol 51:913-21 (1997)
DOI:10.1124/mol.51.6.913

Sequence

[hsa:6580]

Reference

PMID:20103563

Authors

Klaassen CD, Aleksunes LM

Title

Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

Journal

Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014

LinkDB

DBGET integrated database retrieval system