Homo sapiens (human): 7066
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Entry
7066 CDS
T01001
Symbol
THPO, CAMT2, MGDF, MKCSF, ML, MPLLG, THC9, THCYT1, TPO
Name
(RefSeq) thrombopoietin
KO
K06854
thrombopoietin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04081
Hormone signaling
hsa04630
JAK-STAT signaling pathway
hsa04640
Hematopoietic cell lineage
Network
nt06518
JAK-STAT signaling
Element
N01555
Hormone-like-cytokine to Jak-STAT signaling pathway
Disease
H00227
Congenital amegakaryocytic thrombocytopenia
H00978
Thrombocytopenia (THC)
H01612
Essential thrombocythemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
7066 (THPO)
09133 Signaling molecules and interaction
04081 Hormone signaling
7066 (THPO)
04060 Cytokine-cytokine receptor interaction
7066 (THPO)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
7066 (THPO)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
7066 (THPO)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
CSF and other factors
7066 (THPO)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EPO_TPO
CYTL1
Motif
Other DBs
NCBI-GeneID:
7066
NCBI-ProteinID:
NP_000451
OMIM:
600044
HGNC:
11795
Ensembl:
ENSG00000090534
UniProt:
P40225
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(184371935..184379688)
Genome browser
AA seq
353 aa
AA seq
DB search
MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPV
LLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRL
LLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTT
AVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSL
DQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPP
TGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG
NT seq
1062 nt
NT seq
+upstream
nt +downstream
nt
atggagctgactgaattgctcctcgtggtcatgcttctcctaactgcaaggctaacgctg
tccagcccggctcctcctgcttgtgacctccgagtcctcagtaaactgcttcgtgactcc
catgtccttcacagcagactgagccagtgcccagaggttcaccctttgcctacacctgtc
ctgctgcctgctgtggactttagcttgggagaatggaaaacccagatggaggagaccaag
gcacaggacattctgggagcagtgacccttctgctggagggagtgatggcagcacgggga
caactgggacccacttgcctctcatccctcctggggcagctttctggacaggtccgtctc
ctccttggggccctgcagagcctccttggaacccagcttcctccacagggcaggaccaca
gctcacaaggatcccaatgccatcttcctgagcttccaacacctgctccgaggaaaggtg
cgtttcctgatgcttgtaggagggtccaccctctgcgtcaggcgggccccacccaccaca
gctgtccccagcagaacctctctagtcctcacactgaacgagctcccaaacaggacttct
ggattgttggagacaaacttcactgcctcagccagaactactggctctgggcttctgaag
tggcagcagggattcagagccaagattcctggtctgctgaaccaaacctccaggtccctg
gaccaaatccccggatacctgaacaggatacacgaactcttgaatggaactcgtggactc
tttcctggaccctcacgcaggaccctaggagccccggacatttcctcaggaacatcagac
acaggctccctgccacccaacctccagcctggatattctccttccccaacccatcctcct
actggacagtatacgctcttccctcttccacccaccttgcccacccctgtggtccagctc
caccccctgcttcctgacccttctgctccaacgcccacccctaccagccctcttctaaac
acatcctacacccactcccagaatctgtctcaggaagggtaa
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