Homo sapiens (human): 7082 Help Entry 7082              CDS       T01001                                  Symbol TJP1, ZO-1 Name (RefSeq) tight junction protein 1   KO K05701   tight junction protein 1 Organism hsa  Homo sapiens (human) Pathway hsa04520   Adherens junction hsa04530   Tight junction hsa04540   Gap junction hsa05110   Vibrio cholerae infection hsa05120   Epithelial cell signaling in Helicobacter pylori infection hsa05130   Pathogenic Escherichia coli infection Network nt06180  Pathogenic Escherichia coli   Element N01287   Tight junction-Actin signaling pathway N01288   Escherichia EspF to Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     7082 (TJP1)    04530 Tight junction     7082 (TJP1)    04540 Gap junction     7082 (TJP1)  09160 Human Diseases   09171 Infectious disease: bacterial    05110 Vibrio cholerae infection     7082 (TJP1)    05120 Epithelial cell signaling in Helicobacter pylori infection     7082 (TJP1)    05130 Pathogenic Escherichia coli infection     7082 (TJP1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     7082 (TJP1) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Others      7082 (TJP1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PDZ ZU5 PDZ_6 PDZ_2 Guanylate_kin SH3_2 DUF6288 SH3_1 Motif Other DBs NCBI-GeneID:  7082 NCBI-ProteinID:  NP_003248 OMIM:  601009 HGNC:  11827 Ensembl:  ENSG00000104067 UniProt:  Q07157 Q6MZU1 Structure PDBPDBj LinkDB All DBs Position 15:complement(29699367..29969049) Genome browser AA seq 1748 aa AA seqDB search MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVL KGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPD PEPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRRSVASSQ PAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENM SLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHS GRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDEERISKPGAVSTPVKHAD DHTPKTVEEVTVERNEKQTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRP SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIR EEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKG EVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRAD FWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREK LAREEPDIYQIAKSEPRDAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQ WYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMND GWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHT SDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSP QAQPQPIHRIDSPGFKPASQQKAEASSPVPYLSPETNPASSTSAVNHNVNLTNVRLEEPT PAPSTSYSPQADSLRTPSTEAAHIMLRDQEPSLSSHVDPTKVYRKDPYPEEMMRQNHVLK QPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESSSYTDQFSRNYEHRLRY EDRVPMYEEQWSYYDDKQPYPSRPPFDNQHSQDLDSRQHPEESSERGYFPRFEEPAPLSY DSRPRYEQAPRASALRHEEQPAPGYDTHGRLRPEAQPHPSAGPKPAESKQYFEQYSRSYE QVPPQGFTSRAGHFEPLHGAAAVPPLIPSSQHKPEALPSNTKPLPPPPTQTEEEEDPAMK PQSVLTRVKMFENKRSASLETKKDVNDTGSFKPPEVASKPSGAPIIGPKPTSQNQFSEHD KTLYRIPEPQKPQLKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHIAASHL SEPAKPAHSQNQSNFSSYSSKGKPPEADGVDRSFGEKRYEPIQATPPPPPLPSQYAQPSQ PVTSASLHIHSKGAHGEGNSVSLDFQNSLVSKPDPPPSQNKPATFRPPNREDTAQAAFYP QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHK PDLSSKTPTSPKTLVKSHSLAQPPEFDSGVETFSIHAEKPKYQINNISTVPKAIPVSPSA VEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNS ILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANC VSVLIDHF NT seq 5247 nt NT seq  +upstreamnt  +downstreamnt atgtccgccagagctgcggccgccaagagcacagcaatggaggaaacagctatatgggaa caacatacagtgacgcttcacagggctcctggatttggatttggaattgcaatatctggt ggacgagataatcctcattttcagagtggggaaacgtcaatagtgatttcagatgtgctg aaaggaggaccagctgaaggacagctacaggaaaatgaccgagttgcaatggttaacgga gtttcaatggataatgttgaacatgcttttgctgttcagcaactaaggaaaagtgggaaa aatgcaaaaattacaattagaaggaagaagaaagttcaaataccagtaagtcgtcctgat cctgaaccagtatctgataatgaagaagatagttatgatgaggaaatacatgatccaaga agtggccggagtggtgtggttaacagaaggagtgagaagatttggccgagggatagaagt gcaagtagagagaggagcttgtccccgcggtcagacaggcggtcagtggcttccagccag cctgctaaacctactaaagtcacactggtgaaatcccggaaaaatgaagaatatggtctt cgattggcaagccatatatttgttaaggaaatttcacaagatagtttggcagcaagagat ggcaatattcaagaaggtgatgttgtattgaagataaatggtactgtgacagaaaatatg tcattgacagatgcaaagacattgatagaaaggtctaaaggcaaattaaaaatggtagtt caaagagatgaacgggctacgctattgaatgtccctgatctttctgacagcatccactct gctaatgcctctgagagagacgacatttcagaaattcagtcactggcatcagatcattct ggtcgatcacacgataggcctccccgccgcagccggtcacgatctcctgaccagcggtca gagccttctgatcattccaggcactcgccgcagcagccaagcaatggcagtctccggagt agagatgaagagagaatttctaaacctggggctgtctcaactcctgtaaagcatgctgat gatcacacacctaaaacagtggaagaagttacagttgaaagaaatgagaaacaaacacct tctcttccagaaccaaagcctgtgtatgcccaagttgggcaaccagatgtggatttacct gtcagtccatctgatggtgtcctacctaattcaactcatgaagatgggattcttcggccc agcatgaaattggtaaaattcagaaaaggagatagtgtgggtttgcggctggctggtgga aatgatgttggaatatttgtagctggcgttctagaagatagccctgcagccaaggaaggc ttagaggaaggtgatcaaattctcagggtaaacaacgtagattttacaaatatcataaga gaagaagccgtccttttcctgcttgacctccctaaaggagaagaagtgaccatattggct cagaagaagaaggatgtttatcgtcgcattgtagaatcagatgtaggagattctttctat attagaacccattttgaatatgaaaaggaatctccctatggacttagttttaacaaagga gaggtgttccgtgttgtggataccttgtacaatggaaaactgggctcttggcttgctatt cgaattggtaaaaatcataaggaggtagaacgaggcatcatccctaataagaacagagct gagcagctagccagtgtacagtatacacttccaaaaacagcaggcggagaccgtgctgac ttctggagattcagaggtcttcgcagctccaagagaaatcttcgaaaaagcagagaggat ttgtccgctcagcctgttcaaacaaagtttccagcttatgaaagagtggttcttcgagaa gctggatttctgaggcctgtaaccatttttggaccaatagctgatgttgccagagaaaag ctggcaagagaagaaccagatatttatcaaattgcaaagagtgaaccacgagacgctgga actgaccaacgtagctctggcattattcgcctgcatacaataaagcaaatcatagatcaa gacaaacatgctttattagatgtaacaccaaatgcagttgatcgtcttaactatgcccag tggtatccaattgttgtatttcttaaccctgattctaagcaaggagtaaaaacaatgaga atgaggttatgtccagaatctcggaaaagtgccaggaagttatacgagcgatctcataaa cttcgtaaaaataatcaccatctttttacaactacaattaacttaaattcaatgaatgat ggttggtatggtgcgctgaaagaagcaattcaacaacagcaaaaccagctggtatgggtt tccgagggaaaggcggatggtgctacaagtgatgaccttgatttgcatgatgatcgtctg tcctacctgtcagctccaggtagtgaatactcaatgtatagcacggacagtagacacact tctgactatgaagacacagacacagaaggcggggcctacactgatcaagaactagatgaa actcttaatgatgaggttgggactccaccggagtctgccattacacggtcctctgagcct gtaagagaggactcctctggaatgcatcatgaaaaccaaacatatcctccttactcacca caagcgcagccacaaccaattcatagaatagactcccctggatttaagccagcctctcaa cagaaagcagaagcttcatctccagtcccttacctttcgcctgaaacaaacccagcatca tcaacctctgctgttaatcataatgtaaatttaactaatgtcagactggaggagcccacc ccagctccttccacctcttactcaccacaagctgattctttaagaacaccaagtactgag gcagctcacataatgctaagagatcaagaaccatcattgtcgtcgcatgtagatccaaca aaggtgtatagaaaggatccatatcccgaggaaatgatgaggcagaaccatgttttgaaa cagccagccgttagtcacccagggcacaggccagacaaagagcctaatctgacctatgaa ccccaactcccatacgtagagaaacaagccagcagagacctcgagcagcccacatacaga tacgagtcctcaagctatacggaccagttttctcgaaactatgaacatcgtctgcgatac gaagatcgcgtccccatgtatgaagaacagtggtcatattatgatgacaaacagccctac ccatctcggccaccttttgataatcagcactctcaagaccttgactccagacagcatccc gaagagtcctcagaacgagggtactttccacgttttgaagagccagcccctctgtcttac gacagcagaccacgttacgaacaggcacctagagcatccgccctgcggcacgaagagcag ccagctcctgggtatgacacacatggtagactcagaccggaagcccagccccacccttca gcagggcccaagcctgcagagtccaagcagtattttgagcaatattcacgcagttacgag caagtaccaccccaaggatttacctctagagcaggtcattttgagcctctccatggtgct gcagctgtccctccgctgataccttcatctcagcataagccagaagctctgccttcaaac accaaaccactgcctccacccccaactcaaaccgaagaagaggaagatccagcaatgaag ccacagtctgtactcaccagagttaagatgtttgaaaacaaaagatctgcatccttagag accaagaaggatgtaaatgacactggcagttttaagcctccagaagtagcatctaaacct tcaggtgctcccatcattggtcccaaacccacttctcagaatcaattcagtgaacatgac aaaactctgtacaggatcccagaacctcaaaaacctcaactgaagccacctgaagatatt gttcggtccaatcattatgaccctgaagaagatgaagaatattatcgaaaacagctgtca tactttgaccgaagaagttttgagaataagcctcctgcacacattgccgccagccatctc tccgagcctgcaaagccagcgcattctcagaatcaatcaaatttttctagttattcttca aagggaaagcctcctgaagctgatggtgtggatagatcatttggcgagaaacgctatgaa cccatccaggccactccccctcctcctccattgccctcgcagtatgcccagccatctcag cctgtcaccagcgcgtctctccacatacattctaagggagcacatggtgaaggtaattca gtgtcattggattttcagaattccttagtgtccaaaccagacccacctccatctcagaat aagccagcaactttcagaccaccaaaccgagaagatactgctcaggcagctttctatccc cagaaaagttttccagataaagccccagttaatggaactgaacagactcagaaaacagtc actccagcatacaatcgattcacaccaaaaccatatacaagttctgcccgaccatttgaa cgcaagtttgaaagtcctaaattcaatcacaatcttctgccaagtgaaactgcacataaa cctgacttgtcttcaaaaactcccacttctccaaaaactcttgtgaaatcgcacagtttg gcacagcctcctgagtttgacagtggagttgaaactttctctatccatgcagagaagcct aaatatcaaataaataatatcagcacagtgcctaaagctattcctgtgagtccttcagct gtggaagaggatgaagatgaagatggtcatactgtggtggccacagcccgaggcatattt aacagcaatgggggcgtgctgagttccatagaaactggtgttagtataattatccctcaa ggagccattcccgaaggagttgagcaggaaatctatttcaaggtctgccgggacaacagc atccttccacctttagataaagagaaaggtgaaacactgctgagtcctttggtgatgtgt ggtccccatggcctcaagttcctgaagcctgtggagctgcgcttaccacactgtgatcct aaaacctggcaaaacaagtgtcttcccggagatccaaattatctcgttggagcaaactgt gtttctgtccttattgaccacttttaa

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