KEGG   Homo sapiens (human): 7171
Entry
7171              CDS       T01001                                 
Symbol
TPM4, BDPLT25, HEL-S-108
Name
(RefSeq) tropomyosin 4
  KO
K10375  tropomyosin 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04814  Motor proteins
hsa04820  Cytoskeleton in muscle cells
hsa05410  Hypertrophic cardiomyopathy
hsa05414  Dilated cardiomyopathy
Disease
H01235  Bleeding disorder platelet-type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    7171 (TPM4)
   04820 Cytoskeleton in muscle cells
    7171 (TPM4)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    7171 (TPM4)
   04261 Adrenergic signaling in cardiomyocytes
    7171 (TPM4)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    7171 (TPM4)
   05414 Dilated cardiomyopathy
    7171 (TPM4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7171 (TPM4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Tropomyosins
     7171 (TPM4)
SSDB
Motif
Pfam: Tropomyosin CCDC39 Laminin_II DUF3450 CENP-F_leu_zip PUMA_CC FPP Sec2p TMF_DNA_bd CLZ ADIP CALCOCO1 PspA_IM30 DUF724 EzrA ATG16 DUF1664 Nuf2_DHR10-like Exonuc_VII_L DUF745 XhlA HAUS1 Fib_alpha
Other DBs
NCBI-GeneID: 7171
NCBI-ProteinID: NP_003281
OMIM: 600317
HGNC: 12013
Ensembl: ENSG00000167460
UniProt: P67936 V9HW56
LinkDB
Position
19:16067538..16103002
AA seq 248 aa
MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE
EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE
KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ
TLNELNCI
NT seq 747 nt   +upstreamnt  +downstreamnt
atggccggcctcaactccctggaggcggtgaaacgcaagatccaggccctgcagcagcag
gcggacgaggcggaagaccgcgcgcagggcctgcagcgggagctggacggcgagcgcgag
cggcgcgagaaagctgaaggtgatgtggccgccctcaaccgacgcatccagctcgttgag
gaggagttggacagggctcaggaacgactggccacggccctgcagaagctggaggaggca
gaaaaagctgcagatgagagtgagagaggaatgaaggtgatagaaaaccgggccatgaag
gatgaggagaagatggagattcaggagatgcagctcaaagaggccaagcacattgcggaa
gaggctgaccgcaaatacgaggaggtagctcgtaagctggtcatcctggagggtgagctg
gagagggcagaggagcgtgcggaggtgtctgaactaaaatgtggtgacctggaagaagaa
ctcaagaatgttactaacaatctgaaatctctggaggctgcatctgaaaagtattctgaa
aaggaggacaaatatgaagaagaaattaaacttctgtctgacaaactgaaagaggctgag
acccgtgctgaatttgcagagagaacggttgcaaaactggaaaagacaattgatgacctg
gaagagaaacttgcccaggccaaagaagagaacgtgggcttacatcagacactggatcag
acactaaacgaacttaactgtatataa

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