Homo sapiens (human): 7201
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Entry
7201 CDS
T01001
Symbol
TRHR, CHNG7, TRH-R
Name
(RefSeq) thyrotropin releasing hormone receptor
KO
K04282
thyrotropin-releasing hormone receptor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04020
Calcium signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04081
Hormone signaling
Network
nt06322
TRH-TSH-TH signaling
nt06528
Calcium signaling
Element
N00918
TRH-TRHR-PLCB-PKC signaling pathway
N01640
GPCR-PLCB-ITPR signaling pathway
Disease
H00250
Congenital nongoitrous hypothyroidism (CHNG)
H01700
Hypopituitarism
Drug target
Montirelin (
DG01347
):
D02588
D09845
Protirelin (
DG01171
):
D00176
<JP>
D02007
<JP>
Rovatirelin hydrate:
D10594
Taltirelin hydrate:
D01925
<JP>
Thyrotropin alfa:
D06120
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
7201 (TRHR)
04081 Hormone signaling
7201 (TRHR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
7201 (TRHR)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Peptide
Thyrotropin-releasing hormone (TRH)
7201 (TRHR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7TM_GPCR_Srx
7tm_4
Motif
Other DBs
NCBI-GeneID:
7201
NCBI-ProteinID:
NP_003292
OMIM:
188545
HGNC:
12299
Ensembl:
ENSG00000174417
UniProt:
P34981
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:109086585..109121565
Genome browser
AA seq
398 aa
AA seq
DB search
MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPT
NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCG
YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTH
QNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKES
DHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
atggaaaacgagacagtcagtgaactgaaccaaacacagcttcagccacgagcagtggtg
gccttagaataccaggtggtcaccatcttacttgtactcattatttgtggcctgggcatt
gtaggcaacatcatggtagtcctggttgtcatgagaaccaagcacatgaggacccccaca
aactgctacctggtgagcctggcagtagctgatctcatggtcttggtggccgcaggcctc
cccaacataacagacagtatctacggttcctgggtctatggctatgttggatgcctctgc
attacttacctccagtatttgggaattaatgcatcctcttgttcaataacagcctttacc
attgagaggtacatagcaatctgtcaccccatcaaagcccagtttctctgcacattttcc
agagccaaaaagattatcatctttgtctgggctttcacatctctttactgtatgctctgg
ttcttcttgctggatctcaatattagcacctacaaagatgctattgtgatatcctgtggc
tacaagatctccaggaattactactcacctatttacctaatggactttggtgtcttttat
gttgtgccaatgatcctggctaccgtcctctatggattcatagctagaatccttttctta
aatcccattccttcagatcctaaagaaaactctaagacatggaaaaatgattcaacccat
cagaacacaaatctgaatgtaaatacctctaatagatgtttcaacagcacagtatcttca
aggaagcaggtcaccaagatgctggcagtggttgtaattctgtttgcccttttatggatg
ccctacaggactctagtggttgtcaactcatttctctccagtcctttccaagaaaattgg
tttttgctcttttgcagaatttgcatttatctcaacagtgccatcaacccggtgatttac
aatctcatgtcccagaaattccgtgcagccttcagaaagctctgcaactgcaagcagaag
ccaacagagaaacctgctaactacagtgtggccctaaattacagcgtcatcaaggagtca
gaccatttcagcacagagcttgatgatatcactgtcactgacacttacctgtctgccaca
aaagtgtcttttgatgacacctgcttggcttctgaggtatcctttagccaaagttga
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