Homo sapiens (human): 726
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Entry
726 CDS
T01001
Symbol
CAPN5, ADNIV, HTRA3, VRNI, nCL-3
Name
(RefSeq) calpain 5
KO
K08574
calpain-5 [EC:3.4.22.-]
Organism
hsa
Homo sapiens (human)
Disease
H01798
Autosomal dominant neovascular inflammatory vitreoretinopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
726 (CAPN5)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C2: calpain family
726 (CAPN5)
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GFIT
Motif
Pfam:
Peptidase_C2
Calpain_III
C2
Motif
Other DBs
NCBI-GeneID:
726
NCBI-ProteinID:
NP_004046
OMIM:
602537
HGNC:
1482
Ensembl:
ENSG00000149260
UniProt:
O15484
A0A140VKH4
Structure
PDB
PDBj
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Position
11:77066971..77126155
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AA seq
640 aa
AA seq
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MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLYYKGTPGPAVRWKRPKGICED
PRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGI
FHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGG
NTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADM
EARLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSE
EWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLH
GAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGE
NLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHT
GEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLKDSPTGANSYV
IIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKAD
PDNLQALHTLHLRDRNSRQPSNLPGTVAVHILSSTSLMAV
NT seq
1923 nt
NT seq
+upstream
nt +downstream
nt
atgttctcgtgtgtgaagccctatgaggaccagaactactcagccctgaggcgggactgc
cggcgcaggaaggtgctcttcgaggaccccctcttccccgccactgacgactcactctac
tataagggcacgccggggcccgccgtcaggtggaagcgacccaagggcatctgcgaggac
ccccgcctctttgtggatggcatcagctcccacgacctgcaccagggccaggtgggcaac
tgctggtttgtggcagcctgctcgtcacttgcctcccgggagtcgctgtggcaaaaggtc
atcccagactggaaggagcaggaatgggaccccgaaaagcccaacgcctacgcgggcatc
ttccacttccacttctggcgcttcggggaatgggtggacgtggtcatcgatgaccggctg
cccacagtcaacaaccagctcatctactgccactccaactcccgcaatgagttttggtgc
gccctagtggagaaggcctatgccaaactggcaggctgttaccaggccctggatggaggc
aacacagcagacgcactggtggacttcacgggtggtgtttctgagcccatcgacctgacc
gagggtgactttgccaacgatgagactaagaggaaccagctctttgagcgcatgttaaag
gtgcacagccggggcggcctcatcagtgcctccatcaaggcagtgacagcagctgacatg
gaggcccgcctggcgtgcggcctggtaaagggccacgcatacgccgtcactgatgtgcgc
aaggtgcgcctgggccacggcctactggccttcttcaagtcagagaagttggacatgatc
cgcctgcgcaacccctggggcgagcgggagtggaacgggccctggagtgacacctcggag
gagtggcagaaagtgagcaagagtgagcgggagaagatgggtgtgaccgtgcaggacgac
ggtgagttctggatgaccttcgaggacgtgtgccggtacttcacggacatcatcaagtgc
cgcgtgatcaacacatcccacctgagcatccacaagacgtgggaggaggcccggctgcat
ggcgcctggacgctgcatgaggacccgcgacagaaccgcggtggcggctgcatcaaccac
aaggacaccttcttccagaacccacagtacatcttcgaagtcaagaagccagaagatgaa
gtcctgatctgcatccagcagcggccaaagcggtctacgcgccgggagggcaagggtgag
aacctggccattggctttgacatctacaaggtggaggagaaccgccagtaccgcatgcac
agcctgcagcacaaggccgccagctccatctacatcaactcacgcagcgtcttcctgcgc
accgaccagcccgagggccgctatgtcatcatccccacaaccttcgagccaggccacact
ggcgagttcctgctccgagtcttcactgatgtgccctccaactgccgggagctgcgcctg
gatgagcccccacacacctgctggagctccctctgtggctacccccagctggtgacccag
gtacatgtcctgggagctgctggcctcaaggactccccaacaggggctaactcttatgtg
atcatcaagtgtgagggagacaaagtccgctcggctgtgcagaagggcacctccacacca
gagtacaatgtgaaaggcatcttctaccgcaagaagctgagccagcccatcactgtacag
gtctggaaccaccgagtgctgaaggatgaatttctgggccaggtgcacctaaaggctgac
ccggacaacctccaggccctgcataccctccacctccgggaccgaaatagccggcagccc
agcaacctgccaggcactgtggccgtgcacattctcagcagcacctccctcatggctgtc
tga
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