Homo sapiens (human): 7299 Help Entry 7299              CDS       T01001                                  Symbol TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 Name (RefSeq) tyrosinase   KO K00505   tyrosinase [EC:1.14.18.1] Organism hsa  Homo sapiens (human) Pathway hsa00350   Tyrosine metabolism hsa01100   Metabolic pathways hsa04916   Melanogenesis Module hsa_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Network nt06028  Dopamine and serotonin metabolism   Element N01552   Eumelanin biosynthesis Disease H00168   Oculocutaneous albinism Drug target Hydroquinone:  D00073 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     7299 (TYR)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     7299 (TYR) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor     1.14.18.1  tyrosinase      7299 (TYR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tyrosinase Laminin_EGF LapA_dom Nup188_SH3-like Motif Other DBs NCBI-GeneID:  7299 NCBI-ProteinID:  NP_000363 OMIM:  606933 HGNC:  12442 Ensembl:  ENSG00000077498 Pharos:  P14679(Tclin) UniProt:  P14679 L8B082 Structure PDB LinkDB All DBs Position 11:89177875..89295759 Genome browser AA seq 529 aa AA seqDB search MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL NT seq 1590 nt NT seq  +upstreamnt  +downstreamnt atgctcctggctgttttgtactgcctgctgtggagtttccagacctccgctggccatttc cctagagcctgtgtctcctctaagaacctgatggagaaggaatgctgtccaccgtggagc ggggacaggagtccctgtggccagctttcaggcagaggttcctgtcagaatatccttctg tccaatgcaccacttgggcctcaatttcccttcacaggggtggatgaccgggagtcgtgg ccttccgtcttttataataggacctgccagtgctctggcaacttcatgggattcaactgt ggaaactgcaagtttggcttttggggaccaaactgcacagagagacgactcttggtgaga agaaacatcttcgatttgagtgccccagagaaggacaaattttttgcctacctcacttta gcaaagcataccatcagctcagactatgtcatccccatagggacctatggccaaatgaaa aatggatcaacacccatgtttaacgacatcaatatttatgacctctttgtctggatgcat tattatgtgtcaatggatgcactgcttgggggatctgaaatctggagagacattgatttt gcccatgaagcaccagcttttctgccttggcatagactcttcttgttgcggtgggaacaa gaaatccagaagctgacaggagatgaaaacttcactattccatattgggactggcgggat gcagaaaagtgtgacatttgcacagatgagtacatgggaggtcagcaccccacaaatcct aacttactcagcccagcatcattcttctcctcttggcagattgtctgtagccgattggag gagtacaacagccatcagtctttatgcaatggaacgcccgagggacctttacggcgtaat cctggaaaccatgacaaatccagaaccccaaggctcccctcttcagctgatgtagaattt tgcctgagtttgacccaatatgaatctggttccatggataaagctgccaatttcagcttt agaaatacactggaaggatttgctagtccacttactgggatagcggatgcctctcaaagc agcatgcacaatgccttgcacatctatatgaatggaacaatgtcccaggtacagggatct gccaacgatcctatcttccttcttcaccatgcatttgttgacagtatttttgagcagtgg ctccgaaggcaccgtcctcttcaagaagtttatccagaagccaatgcacccattggacat aaccgggaatcctacatggttccttttataccactgtacagaaatggtgatttctttatt tcatccaaagatctgggctatgactatagctatctacaagattcagacccagactctttt caagactacattaagtcctatttggaacaagcgagtcggatctggtcatggctccttggg gcggcgatggtaggggccgtcctcactgccctgctggcagggcttgtgagcttgctgtgt cgtcacaagagaaagcagcttcctgaagaaaagcagccactcctcatggagaaagaggat taccacagcttgtatcagagccatttataa

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