Homo sapiens (human): 731 Help Entry 731               CDS       T01001                                  Symbol C8A Name (RefSeq) complement C8 alpha chain   KO K03997   complement component 8 subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     731 (C8A)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     731 (C8A)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     731 (C8A)   09174 Infectious disease: parasitic    05146 Amoebiasis     731 (C8A)   09163 Immune disease    05322 Systemic lupus erythematosus     731 (C8A)   09164 Neurodegenerative disease    05020 Prion disease     731 (C8A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF EGF_C8A_B_C6 Ldl_recept_a TSP_1 TSP1_spondin Motif Other DBs NCBI-GeneID:  731 NCBI-ProteinID:  NP_000553 OMIM:  120950 HGNC:  1352 Ensembl:  ENSG00000157131 UniProt:  P07357 Structure PDBPDBj LinkDB All DBs Position 1:56854797..56918223 Genome browser AA seq 584 aa AA seqDB search MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRH RSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQD CLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETV YNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKV KKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAH FKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKA KMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDII SRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKR QNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADG SWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC NT seq 1755 nt NT seq  +upstreamnt  +downstreamnt atgtttgctgttgttttcttcatcttgtctttgatgacttgtcagcctggggtaactgca caggagaaggtgaaccagagagtaagacgggcagctacacccgcagcagttacctgccag ctgagcaactggtcagagtggacagattgctttccgtgccaggacaaaaagtaccgacac cggagcctcttgcagccaaacaagtttgggggaaccatctgcagtggtgacatctgggat caagccagctgctccagttctacaacttgtgtaaggcaagcacagtgtggacaggatttc cagtgtaaggagacaggtcgctgcctgaaacgccaccttgtgtgtaatggagaccaggac tgccttgatggctctgatgaggacgactgtgaagatgtcagggccattgacgaagactgc agccagtatgaaccaattccaggatcacagaaggcagccttggggtacaatatcctgacc caggaagatgctcagagtgtgtacgatgccagttattatgggggccagtgtgagacggta tacaatggggaatggagggagcttcgatatgactccacctgtgaacgtctctactatgga gatgatgagaaatactttcggaaaccctacaactttctgaagtaccactttgaagccctg gcagatactggaatctcctcagagttttatgataatgcaaatgaccttctttccaaagtt aaaaaagacaagtctgactcatttggagtgaccatcggcataggcccagccggcagccct ttattggtgggtgtaggtgtatcccactcacaagacacttcattcttgaacgaattaaac aagtataatgagaagaaattcattttcacaagaatcttcacaaaggtgcagactgcacat tttaagatgaggaaggatgacattatgctggatgaaggaatgctgcagtcattaatggag cttccagatcagtacaattatggcatgtatgccaagttcatcaatgactatggcacccat tacatcacatctggatccatgggtggcatttatgaatatatcctggtgattgacaaagca aaaatggaatcccttggtattaccagcagagatatcacgacatgttttggaggctccttg ggcattcaatatgaagacaaaataaatgttggtggaggtttatcaggagaccattgtaaa aaatttggaggtggcaaaactgaaagggccaggaaggccatggctgtggaagacattatt tctcgggtgcgaggtggcagttctggctggagcggtggcttggcacagaacaggagcacc attacataccgttcctgggggaggtcattaaagtataatcctgttgttatcgattttgag atgcagcctatccacgaggtgctgcggcacacaagcctggggcctctggaggccaagcgc cagaacctgcgccgcgccttggaccagtatctgatggaattcaatgcctgccgatgtggg ccttgcttcaacaatggggtgcccatcctcgagggcaccagctgcaggtgccagtgccgc ctgggtagcttgggtgctgcctgtgagcaaacacagacagaaggagccaaagcagatggg agctggagttgctggagctcctggtctgtatgcagagcaggcatccaggaaaggagaaga gagtgtgacaatccagcacctcagaatggaggggcctcgtgtccagggcggaaagtacag acgcaggcttgctga

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