KEGG   NETWORK: N01490
Entry
N01490                      Network                                
Name
Common pathway of complement cascade, MAC formation
Definition
C5 -- ((C4b+C2a+C3b),(C3b+Bb+C3b)) -> C5b -> (C5b+C6+C7+C8+C9)
  Expanded
727 -- ((C22542+C22531+C22533),(C22533+C22540+C22533)) -> C22545 -> (C22545+729+730+(731,732,733)+735)
Class
nt06513 Complement cascade
Type
Reference
Pathway
hsa04610  Complement and coagulation cascades
Gene
727  C5; complement C5
729  C6; complement C6
730  C7; complement C7
731  C8A; complement C8 alpha chain
732  C8B; complement C8 beta chain
733  C8G; complement C8 gamma chain
735  C9; complement C9
Metabolite
C22542  Complement component 4b
C22531  Complement component 2a
C22533  Complement component 3b
C22540  Complement factor Bb
C22545  Complement component 5b
Reference
PMID:26082779
  Authors
Merle NS, Church SE, Fremeaux-Bacchi V, Roumenina LT
  Title
Complement System Part I - Molecular Mechanisms of Activation and Regulation.
  Journal
Front Immunol 6:262 (2015)
DOI:10.3389/fimmu.2015.00262
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