Homo sapiens (human): 7443
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Entry
7443 CDS
T01001
Symbol
VRK1, HMNR10, PCH1, PCH1A
Name
(RefSeq) VRK serine/threonine kinase 1
KO
K08816
vaccinia related kinase [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Disease
H00856
Distal hereditary motor neuropathies
H00897
Pontocerebellar hypoplasia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
7443 (VRK1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
7443 (VRK1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CK1 group
VRK family
7443 (VRK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
EcKL
Pox_ser-thr_kin
RIO1
TCAD9
Motif
Other DBs
NCBI-GeneID:
7443
NCBI-ProteinID:
NP_003375
OMIM:
602168
HGNC:
12718
Ensembl:
ENSG00000100749
UniProt:
Q99986
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:96797382..96881609
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AA seq
396 aa
AA seq
DB search
MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE
SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atgcctcgtgtaaaagcagctcaagctggaagacagagctctgcaaagagacatcttgca
gaacaatttgcagttggagagataataactgacatggcaaaaaaggaatggaaagtagga
ttacccattggccaaggaggctttggctgtatatatcttgctgatatgaattcttcagag
tcagttggcagtgatgcaccttgtgttgtaaaagtggaacccagtgacaatggacctctt
tttactgaattaaagttctaccaacgagctgcaaaaccagagcaaattcagaaatggatt
cgtacccgtaagctgaagtacctgggtgttcctaagtattgggggtctggtctacatgac
aaaaatggaaaaagttacaggtttatgataatggatcgctttgggagtgaccttcagaaa
atatatgaagcaaatgccaaaaggttttctcggaaaactgtcttgcagctaagcttaaga
attctggatattctggaatatattcacgagcatgagtatgtgcatggagatatcaaggcc
tcaaatcttcttctgaactacaagaatcctgaccaggtgtacttggtagattatggcctt
gcttatcggtactgcccagaaggagttcataaagaatacaaagaagaccccaaaagatgt
cacgatggcactattgaattcacgagcatcgatgcacacaatggcgtggccccatcaaga
cgtggtgatttggaaatacttggttattgcatgatccaatggcttactggccatcttcct
tgggaggataatttgaaagatcctaaatatgttagagattccaaaattagatacagagaa
aatattgcaagtttgatggacaaatgttttcctgagaaaaacaaaccaggtgaaattgcc
aaatacatggaaacagtgaaattactagactacactgaaaaacctctttatgaaaattta
cgtgacattcttttgcaaggactaaaagctataggaagtaaggatgatggcaaattggac
ctcagtgttgtggagaatggaggtttgaaagcaaaaacaataacaaagaagcgaaagaaa
gaaattgaagaaagcaaggaacctggtgttgaagatacggaatggtcaaacacacagaca
gaggaggccatacagacccgttcaagaaccagaaagagagtccagaagtaa
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