Homo sapiens (human): 7494
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Entry
7494 CDS
T01001
Symbol
XBP1, TREB-5, TREB5, XBP-1, XBP2
Name
(RefSeq) X-box binding protein 1
KO
K09027
X box-binding protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04141
Protein processing in endoplasmic reticulum
hsa04932
Non-alcoholic fatty liver disease
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05017
Spinocerebellar ataxia
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05417
Lipid and atherosclerosis
Network
nt06460
Alzheimer disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
nt06534
Unfolded protein response
Element
N01011
IRE1a-XBP1 signaling pathway
N01012
Mutation-caused aberrant PSEN1 to IRE1a-XBP1 signaling pathway
N01015
ATF6-mediated transcription
N01016
Mutation-caused aberrant PSEN1 to ATF6-mediated transcription
N01034
Mutation-caused aberrant SNCA to IRE1a-XBP1 signaling pathway
N01148
Mutation-caused aberrant SOD1 to IRE1a-XBP1 signaling pathway
Disease
H01653
Bipolar disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
7494 (XBP1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
7494 (XBP1)
05012 Parkinson disease
7494 (XBP1)
05014 Amyotrophic lateral sclerosis
7494 (XBP1)
05017 Spinocerebellar ataxia
7494 (XBP1)
05022 Pathways of neurodegeneration - multiple diseases
7494 (XBP1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
7494 (XBP1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
7494 (XBP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
7494 (XBP1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, Jun
7494 (XBP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bZIP_1
bZIP_2
bZIP_Maf
KASH_CCD
YabA
DUF2408
Motif
Other DBs
NCBI-GeneID:
7494
NCBI-ProteinID:
NP_005071
OMIM:
194355
HGNC:
12801
Ensembl:
ENSG00000100219
Pharos:
P17861
(Tbio)
UniProt:
P17861
Structure
PDB
PDBj
LinkDB
All DBs
Position
22:complement(28794560..28800569)
Genome browser
AA seq
261 aa
AA seq
DB search
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK
RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR
EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL
SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP
YQPPFLCQWGRHQPSWKPLMN
NT seq
786 nt
NT seq
+upstream
nt +downstream
nt
atggtggtggtggcagccgcgccgaacccggccgacgggacccctaaagttctgcttctg
tcggggcagcccgcctccgccgccggagccccggccggccaggccctgccgctcatggtg
ccagcccagagaggggccagcccggaggcagcgagcggggggctgccccaggcgcgcaag
cgacagcgcctcacgcacctgagccccgaggagaaggcgctgaggaggaaactgaaaaac
agagtagcagctcagactgccagagatcgaaagaaggctcgaatgagtgagctggaacag
caagtggtagatttagaagaagagaaccaaaaacttttgctagaaaatcagcttttacga
gagaaaactcatggccttgtagttgagaaccaggagttaagacagcgcttggggatggat
gccctggttgctgaagaggaggcggaagccaaggggaatgaagtgaggccagtggccggg
tctgctgagtccgcagcactcagactacgtgcacctctgcagcaggtgcaggcccagttg
tcacccctccagaacatctccccatggattctggcggtattgactcttcagattcagagt
ctgatatcctgttgggcattctggacaacttggacccagtcatgttcttcaaatgccctt
ccccagagcctgccagcctggaggagctcccagaggtctacccagaaggacccagttcct
taccagcctccctttctctgtcagtggggacgtcatcagccaagctggaagccattaatg
aactaa
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integrated database retrieval system