Homo sapiens (human): 7525
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Entry
7525 CDS
T01001
Symbol
YES1, HsT441, P61-YES, Yes, c-yes
Name
(RefSeq) YES proto-oncogene 1, Src family tyrosine kinase
KO
K05705
tyrosine-protein kinase Yes [EC:
2.7.10.2
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04520
Adherens junction
Drug target
Dasatinib (
DG00714
):
D03658
<JP>
D06414
<JP/US>
D12609
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
7525 (YES1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
7525 (YES1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
7525 (YES1)
Protein kinases [BR:
hsa01001
]
Non-receptor tyrosine kinases
SRC family
7525 (YES1)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
7525 (YES1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
Haspin_kinase
SH3_10
zf-RING_14
ABC1
DUF7063
SH3_3
Motif
Other DBs
NCBI-GeneID:
7525
NCBI-ProteinID:
NP_005424
OMIM:
164880
HGNC:
12841
Ensembl:
ENSG00000176105
UniProt:
P07947
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:complement(721588..812753)
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AA seq
543 aa
AA seq
DB search
MGCIKSKENKSPAIKYRPENTPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMT
PFGGSSGVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQI
INNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRG
IFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHY
TEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT
KVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFL
KEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARL
IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNRE
VLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPG
ENL
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcattaaaagtaaagaaaacaaaagtccagccattaaatacagacctgaaaat
actccagagcctgtcagtacaagtgtgagccattatggagcagaacccactacagtgtca
ccatgtccgtcatcttcagcaaagggaacagcagttaatttcagcagtctttccatgaca
ccatttggaggatcctcaggggtaacgccttttggaggtgcatcttcctcattttcagtg
gtgccaagttcatatcctgctggtttaacaggtggtgttactatatttgtggccttatat
gattatgaagctagaactacagaagacctttcatttaagaagggtgaaagatttcaaata
attaacaatacggaaggagattggtgggaagcaagatcaatcgctacaggaaagaatggt
tatatcccgagcaattatgtagcgcctgcagattccattcaggcagaagaatggtatttt
ggcaaaatggggagaaaagatgctgaaagattacttttgaatcctggaaatcaacgaggt
attttcttagtaagagagagtgaaacaactaaaggtgcttattccctttctattcgtgat
tgggatgagataaggggtgacaatgtgaaacactacaaaattaggaaacttgacaatggt
ggatactatatcacaaccagagcacaatttgatactctgcagaaattggtgaaacactac
acagaacatgctgatggtttatgccacaagttgacaactgtgtgtccaactgtgaaacct
cagactcaaggtctagcaaaagatgcttgggaaatccctcgagaatctttgcgactagag
gttaaactaggacaaggatgtttcggcgaagtgtggatgggaacatggaatggaaccacg
aaagtagcaatcaaaacactaaaaccaggtacaatgatgccagaagctttccttcaagaa
gctcagataatgaaaaaattaagacatgataaacttgttccactatatgctgttgtttct
gaagaaccaatttacattgtcactgaatttatgtcaaaaggaagcttattagatttcctt
aaggaaggagatggaaagtatttgaagcttccacagctggttgatatggctgctcagatt
gctgatggtatggcatatattgaaagaatgaactatattcaccgagatcttcgggctgct
aatattcttgtaggagaaaatcttgtgtgcaaaatagcagactttggtttagcaaggtta
attgaagacaatgaatacacagcaagacaaggtgcaaaatttccaatcaaatggacagct
cctgaagctgcactgtatggtcggtttacaataaagtctgatgtctggtcatttggaatt
ctgcaaacagaactagtaacaaagggccgagtgccatatccaggtatggtgaaccgtgaa
gtattagaacaagtggagcgaggatacaggatgccgtgccctcagggctgtccagaatcc
ctccatgaattgatgaatctgtgttggaagaaggaccctgatgaaagaccaacatttgaa
tatattcagtccttcttggaagactacttcactgctacagagccacagtaccagccagga
gaaaatttataa
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integrated database retrieval system
