Homo sapiens (human): 783
Help
Entry
783 CDS
T01001
Symbol
CACNB2, CAB2, CACNLB2, CAVB2, MYSB
Name
(RefSeq) voltage-dependent L-type calcium channel subunit beta-2 isoform 2
KO
K04863
voltage-dependent calcium channel beta-2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04260
Cardiac muscle contraction
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04921
Oxytocin signaling pathway
hsa05410
Hypertrophic cardiomyopathy
hsa05412
Arrhythmogenic right ventricular cardiomyopathy
hsa05414
Dilated cardiomyopathy
Network
nt06528
Calcium signaling
Element
N01637
Ca2+ entry, Voltage-gated Ca2+ channel
N01638
Skeletal-type VGCC-RYR signaling
N01639
Cardiac-type VGCC-RYR signaling
Disease
H00728
Brugada syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
783 (CACNB2)
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
783 (CACNB2)
09153 Circulatory system
04260 Cardiac muscle contraction
783 (CACNB2)
04261 Adrenergic signaling in cardiomyocytes
783 (CACNB2)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
783 (CACNB2)
05412 Arrhythmogenic right ventricular cardiomyopathy
783 (CACNB2)
05414 Dilated cardiomyopathy
783 (CACNB2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
783 (CACNB2)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
783 (CACNB2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_kin
VGCC_beta4Aa_N
SH3_1
Motif
Other DBs
NCBI-GeneID:
783
NCBI-ProteinID:
NP_963890
OMIM:
600003
HGNC:
1402
Ensembl:
ENSP00000320025.8
UniProt:
Q08289
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:18140424..18543557
Genome browser
AA seq
660 aa
AA seq
DB search
MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS
SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR
TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE
NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIP
ANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMM
QKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIER
IFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLN
VQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTL
ATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHN
HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDH
RHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
NT seq
1983 nt
NT seq
+upstream
nt +downstream
nt
atggtccaaagggacatgtccaagtcgcctcccacagcggcggcggcggtggcgcaggag
atccagatggaactgctagagaacgtggctcccgcgggggcgctcggagccgccgcacag
tcatatggaaaaggagccagaaggaaaaacagatttaaaggatctgatggaagcacgtca
tctgatactacctcaaatagttttgttcgccagggttcggcagactcctacactagccgt
ccatccgattccgatgtatctctggaggaggaccgggaggcagtgcgcagagaagcggag
cggcaggcccaggcacagttggaaaaagcaaagacaaagcccgttgcatttgcggttcgg
acaaatgtcagctacagtgcggcccatgaagatgatgttccagtgcctggcatggccatc
tcattcgaagcaaaagattttctgcatgttaaggaaaaatttaacaatgactggtggata
gggcgattggtaaaagaaggctgtgaaatcggattcattccaagcccagtcaaactagaa
aacatgaggctgcagcatgaacagagagccaagcaagggaaattctactccagtaaatca
ggaggaaattcatcatccagtttgggtgacatagtacctagttccagaaaatcaacacct
ccatcatctgctatagacatagatgctactggcttagatgcagaagaaaatgatattcca
gcaaaccaccgctcccctaaacccagtgcaaacagtgtaacgtcaccccactccaaagag
aaaagaatgcccttctttaagaagacagagcacactcctccgtatgatgtggtaccttcc
atgcgaccagtggtcctagtgggcccttctctgaagggctacgaggtcacagatatgatg
caaaaagcgctgtttgattttttaaaacacagatttgaagggcggatatccatcacaagg
gtcaccgctgacatctcgcttgccaaacgctcggtattaaacaatcccagtaagcacgca
ataatagaaagatccaacacaaggtcaagcttagcggaagttcagagtgaaatcgaaagg
atttttgaacttgcaagaacattgcagttggtggtccttgacgcggatacaattaatcat
ccagctcaactcagtaaaacctccttggcccctattatagtatatgtaaagatttcttct
cctaaggttttacaaaggttaataaaatctcgagggaaatctcaagctaaacacctcaac
gtccagatggtagcagctgataaactggctcagtgtcctccagagctgttcgatgtgatc
ttggatgagaaccagcttgaggatgcctgtgagcaccttgccgactatctggaggcctac
tggaaggccacccatcctcccagcagtagcctccccaaccctctccttagccgtacatta
gccacttcaagtctgcctcttagccccaccctagcctctaattcacagggttctcaaggt
gatcagaggactgatcgctccgctcctatccgttctgcttcccaagctgaagaagaacct
agtgtggaaccagtcaagaaatcccagcaccgctcttcctcctcagccccacaccacaac
catcgcagtgggacaagtcgcggcctctccaggcaagagacatttgactcggaaacccag
gagagtcgagactctgcctacgtagagccaaaggaagattattcccatgaccacgtggac
cactatgcctcacaccgtgaccacaaccacagagacgagacccacgggagcagtgaccac
agacacagggagtcccggcaccgttcccgggacgtggatcgagagcaggaccacaacgag
tgcaacaagcagcgcagccgtcataaatccaaggatcgctactgtgaaaaggatggagaa
gtgatatcaaaaaaacggaatgaggctggggagtggaacagggatgtttacatccgccaa
tga
DBGET
integrated database retrieval system
