KEGG   Homo sapiens (human): 79023
Entry
79023             CDS       T01001                                 
Symbol
NUP37, MCPH24, p37
Name
(RefSeq) nucleoporin 37
  KO
K14302  nuclear pore complex protein Nup37
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05014  Amyotrophic lateral sclerosis
Network
nt06464  Amyotrophic lateral sclerosis
  Element
N01152  Nuclear export of mRNA
N01153  Mutation-caused aberrant GLE1 to nuclear export of mRNA
Disease
H00269  Primary microcephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    79023 (NUP37)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    79023 (NUP37)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    79023 (NUP37)
   03036 Chromosome and associated proteins [BR:hsa03036]
    79023 (NUP37)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Nuclear pore complex
     79023 (NUP37)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    79023 (NUP37)
SSDB
Motif
Pfam: WD40 WD40_CDC20-Fz WD40_WDHD1_1st WD40_Prp19 Beta-prop_WDR90_POC16_2nd Beta-prop_EML_2 Beta-prop_CAF1B_HIR1 WD40_RFWD3 Beta-prop_WDR75_1st WDR55 ANAPC4_WD40 WD40_MABP1-WDR62_2nd Beta-prop_RIG_2nd WDR90_beta-prop_4th Beta-prop_TEP1_2nd Beta-prop_TEP1_C Beta-prop_WDR19_1st
Other DBs
NCBI-GeneID: 79023
NCBI-ProteinID: NP_076962
OMIM: 609264
HGNC: 29929
Ensembl: ENSG00000075188
UniProt: Q8NFH4
Structure
LinkDB
Position
12:complement(102073103..102120114)
AA seq 326 aa
MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGTCTFQEEEADVEG
IQYKTLRTFHHGVRVDGIAWSPETRLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVL
EGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNLEGVQTAHFVLHSPGMSVCWHPEETFK
LMVAEKNGTIRFYDLLAQQAILSLESEQVPLMSAHWCLKNTFKVGAVAGNDWLIWDITRS
SYPQNKRPVHMDRACLFRWSTISENLFATTGYPGKMASQFQIHHLGHPQPILMGSVAVGS
GLSWHRTLPLCVIGGDHKLLFWVTEV
NT seq 981 nt   +upstreamnt  +downstreamnt
atgaagcaagatgcctcaagaaatgctgcctacactgtggattgtgaagattatgtgcat
gtggtagaatttaatccctttgagaatggggattcaggaaacctaattgcatatggtggc
aataattatgtggtcattggcacgtgtacgtttcaggaagaagaagcagacgttgaaggc
attcagtataaaacacttcgaacatttcaccatggagtcagggttgatggcatagcttgg
agcccagagactagacttgattcattgcctccagtaatcaaattttgtacttcagctgct
gatatgaaaattagattatttacttcagatcttcaggataaaaatgaatataaggtttta
gagggccataccgatttcattaatggtttggtgtttgatcccaaagaaggccaagaaatt
gcaagtgtgagtgacgatcacacctgcaggatttggaacttggaaggagtgcaaacagct
cattttgttcttcattctcctggcatgagtgtgtgctggcatcctgaggagacttttaag
ctaatggttgcagagaagaatggaacaatccggttttatgatcttttggcccaacaggct
attttatctcttgaatcagaacaagtgccattaatgtcagcacactggtgcttaaaaaac
accttcaaagttggagccgttgcaggaaatgattggttaatttgggatattactcggtcc
agttatcctcaaaataagagacctgttcacatggatcgagcctgcttattcaggtggtcc
acaattagtgaaaatctgtttgcaaccactggttatcctggcaaaatggcaagccagttt
caaattcatcatttaggacaccctcagcccatcctcatgggttctgtagccgttggatct
ggactgtcctggcatcgaactctccctctgtgtgtaattggaggagaccacaagctgttg
ttttgggtgactgaagtataa

DBGET integrated database retrieval system