Homo sapiens (human): 79054
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Entry
79054 CDS
T01001
Symbol
TRPM8, LTRPC6, LTrpC-6, TRPP8, trp-p8
Name
(RefSeq) transient receptor potential cation channel subfamily M member 8 isoform 1
KO
K04983
transient receptor potential cation channel subfamily M member 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa04750
Inflammatory mediator regulation of TRP channels
Drug target
Acoltremon:
D13125
<US>
Menthol (
DG01385
):
D00064
<JP>
D04849
D04918
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
79054 (TRPM8)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
79054 (TRPM8)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Transient receptor potential channel (TRP)
79054 (TRPM8)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TRPM2
LSDAT_euk
LSDAT_prok
YVC1_C
Ion_trans
YqxI
LHD_TRPY1
Motif
Other DBs
NCBI-GeneID:
79054
NCBI-ProteinID:
NP_076985
OMIM:
606678
HGNC:
17961
Ensembl:
ENSP00000323926.4
UniProt:
Q7Z2W7
W8DTH1
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:233917373..234019522
Genome browser
AA seq
1104 aa
AA seq
DB search
MSFRAARLSMRNRRNDTLDSTRTLYSSASRSTDLSYSESDLVNFIQANFKKRECVFFTKD
SKATENVCKCGYAQSQHMEGTQINQSEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYIRL
SCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIL
TGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGYFLAQY
LMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQDSNYGGKIP
IVCFAQGGGKETLKAINTSIKNKIPCVVVEGSGQIADVIASLVEVEDALTSSAVKEKLVR
FLPRTVSRLPEEETESWIKWLKEILECSHLLTVIKMEEAGDEIVSNAISYALYKAFSTSE
QDKDNWNGQLKLLLEWNQLDLANDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLEN
GLNLRKFLTHDVLTELFSNHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRGFRKEDR
NGRDEMDIELHDVSPITRHPLQALFIWAILQNKKELSKVIWEQTRGCTLAALGASKLLKT
LAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELA
VEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGFVSFRKKPVDKH
KKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFC
DEVRQWYVNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFT
LRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIF
RSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLV
CIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAY
FYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRH
RFRQLDTKLNDLKGLLKEIANKIK
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atgtcctttcgggcagccaggctcagcatgaggaacagaaggaatgacactctggacagc
acccggaccctgtactccagcgcgtctcggagcacagacttgtcttacagtgaaagcgac
ttggtgaattttattcaagcaaattttaagaaacgagaatgtgtcttctttaccaaagat
tccaaggccacggagaatgtgtgcaagtgtggctatgcccagagccagcacatggaaggc
acccagatcaaccaaagtgagaaatggaactacaagaaacacaccaaggaatttcctacc
gacgcctttggggatattcagtttgagacactggggaagaaagggaagtatatacgtctg
tcctgcgacacggacgcggaaatcctttacgagctgctgacccagcactggcacctgaaa
acacccaacctggtcatttctgtgaccgggggcgccaagaacttcgccctgaagccgcgc
atgcgcaagatcttcagccggctcatctacatcgcgcagtccaaaggtgcttggattctc
acgggaggcacccattatggcctgatgaagtacatcggggaggtggtgagagataacacc
atcagcaggagttcagaggagaatattgtggccattggcatagcagcttggggcatggtc
tccaaccgggacaccctcatcaggaattgcgatgctgagggctattttttagcccagtac
cttatggatgacttcacaagagatccactgtatatcctggacaacaaccacacacatttg
ctgctcgtggacaatggctgtcatggacatcccactgtcgaagcaaagctccggaatcag
ctagagaagtatatctctgagcgcactattcaagattccaactatggtggcaagatcccc
attgtgtgttttgcccaaggaggtggaaaagagactttgaaagccatcaatacctccatc
aaaaataaaattccttgtgtggtggtggaaggctcgggccagatcgctgatgtgatcgct
agcctggtggaggtggaggatgccctgacatcttctgccgtcaaggagaagctggtgcgc
tttttaccccgcacggtgtcccggctgcctgaggaggagactgagagttggatcaaatgg
ctcaaagaaattctcgaatgttctcacctattaacagttattaaaatggaagaagctggg
gatgaaattgtgagcaatgccatctcctacgctctatacaaagccttcagcaccagtgag
caagacaaggataactggaatgggcagctgaagcttctgctggagtggaaccagctggac
ttagccaatgatgagattttcaccaatgaccgccgatgggagtctgctgaccttcaagaa
gtcatgtttacggctctcataaaggacagacccaagtttgtccgcctctttctggagaat
ggcttgaacctacggaagtttctcacccatgatgtcctcactgaactcttctccaaccac
ttcagcacgcttgtgtaccggaatctgcagatcgccaagaattcctataatgatgccctc
ctcacgtttgtctggaaactggttgcgaacttccgaagaggcttccggaaggaagacaga
aatggccgggacgagatggacatagaactccacgacgtgtctcctattactcggcacccc
ctgcaagctctcttcatctgggccattcttcagaataagaaggaactctccaaagtcatt
tgggagcagaccaggggctgcactctggcagccctgggagccagcaagcttctgaagact
ctggccaaagtgaagaacgacatcaatgctgctggggagtccgaggagctggctaatgag
tacgagacccgggctgttgagctgttcactgagtgttacagcagcgatgaagacttggca
gaacagctgctggtctattcctgtgaagcttggggtggaagcaactgtctggagctggcg
gtggaggccacagaccagcatttcatcgcccagcctggggtccagaattttctttctaag
caatggtatggagagatttcccgagacaccaagaactggaagattatcctgtgtctgttt
attatacccttggtgggctgtggctttgtatcatttaggaagaaacctgtcgacaagcac
aagaagctgctttggtactatgtggcgttcttcacctcccccttcgtggtcttctcctgg
aatgtggtcttctacatcgccttcctcctgctgtttgcctacgtgctgctcatggatttc
cattcggtgccacacccccccgagctggtcctgtactcgctggtctttgtcctcttctgt
gatgaagtgagacagtggtacgtaaatggggtgaattattttactgacctgtggaatgtg
atggacacgctggggcttttttacttcatagcaggaattgtatttcggctccactcttct
aataaaagctctttgtattctggacgagtcattttctgtctggactacattattttcact
ctaagattgatccacatttttactgtaagcagaaacttaggacccaagattataatgctg
cagaggatgctgatcgatgtgttcttcttcctgttcctctttgcggtgtggatggtggcc
tttggcgtggccaggcaagggatccttaggcagaatgagcagcgctggaggtggatattc
cgttcggtcatctacgagccctacctggccatgttcggccaggtgcccagtgacgtggat
ggtaccacgtatgactttgcccactgcaccttcactgggaatgagtccaagccactgtgt
gtggagctggatgagcacaacctgccccggttccccgagtggatcaccatccccctggtg
tgcatctacatgttatccaccaacatcctgctggtcaacctgctggtcgccatgtttggc
tacacggtgggcaccgtccaggagaacaatgaccaggtctggaagttccagaggtacttc
ctggtgcaggagtactgcagccgcctcaatatccccttccccttcatcgtcttcgcttac
ttctacatggtggtgaagaagtgcttcaagtgttgctgcaaggagaaaaacatggagtct
tctgtctgctgtttcaaaaatgaagacaatgagactctggcatgggagggtgtcatgaag
gaaaactaccttgtcaagatcaacacaaaagccaacgacacctcagaggaaatgaggcat
cgatttagacaactggatacaaagcttaatgatctcaagggtcttctgaaagagattgct
aataaaatcaaataa
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