KEGG   Homo sapiens (human): 79154
Entry
79154             CDS       T01001                                 
Symbol
DHRS11, ARPG836, SDR24C1, spDHRS11
Name
(RefSeq) dehydrogenase/reductase 11
  KO
K22970  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00140  Steroid hormone biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    79154 (DHRS11)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     79154 (DHRS11)
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     79154 (DHRS11)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase GDP_Man_Dehyd NmrA NAD_binding_10 F420_oxidored RmlD_sub_bind Shikimate_DH Sacchrp_dh_NADP Guanylin DUF4454 NYAP_N
Other DBs
NCBI-GeneID: 79154
NCBI-ProteinID: NP_077284
OMIM: 616159
HGNC: 28639
Ensembl: ENSG00000278535
UniProt: Q6UWP2
Structure
LinkDB
Position
17:36591879..36600804
AA seq 260 aa
MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGY
PGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNV
NVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGL
RQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVL
STPAHIQIGDIQMRPTEQVT
NT seq 783 nt   +upstreamnt  +downstreamnt
atggccaggcccggcatggagcggtggcgcgaccggctggcgctggtgacgggggcctcg
gggggcatcggcgcggccgtggcccgggccctggtccagcagggactgaaggtggtgggc
tgcgcccgcactgtgggcaacatcgaggagctggctgctgaatgtaagagtgcaggctac
cccgggactttgatcccctacagatgtgacctatcaaatgaagaggacatcctctccatg
ttctcagctatccgttctcagcacagcggtgtagacatctgcatcaacaatgctggcttg
gcccggcctgacaccctgctctcaggcagcaccagtggttggaaggacatgttcaatgtg
aacgtgctggccctcagcatctgcacacgggaagcctaccagtccatgaaggagcggaat
gtggacgatgggcacatcattaacatcaatagcatgtctggccaccgagtgttacccctg
tctgtgacccacttctatagtgccaccaagtatgccgtcactgcgctgacagagggactg
aggcaagagcttcgggaggcccagacccacatccgagccacgtgcatctctccaggtgtg
gtggagacacaattcgccttcaaactccacgacaaggaccctgagaaggcagctgccacc
tatgagcaaatgaagtgtctcaaacccgaggatgtggccgaggctgttatctacgtcctc
agcacccccgcacacatccagattggagacatccagatgaggcccacggagcaggtgacc
tag

DBGET integrated database retrieval system