KEGG T01001: 81607

Homo sapiens (human): 81607

Entry

81607             CDS       T01001

Symbol

NECTIN4, EDSS1, LNIR, PRR4, PVRL4, nectin-4

Name

(RefSeq) nectin cell adhesion molecule 4

K06593

poliovirus receptor-related 4

Organism

hsa Homo sapiens (human)

Pathway

hsa03265

Virion - Ebolavirus, Lyssavirus and Morbillivirus

hsa04520

Adherens junction

Disease

H00647

Ectodermal dysplasia-syndactyly syndrome

Drug target

Enfortumab:

D11524

Enfortumab vedotin:

D11525<JP/US>

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
    81607 (NECTIN4)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    81607 (NECTIN4)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    81607 (NECTIN4)
Cell adhesion molecules [BR:hsa04515]
Immunoglobulin superfamily
  Nectin family
   81607 (NECTIN4)

SSDB

Motif

Pfam:

V-set Ig_3 C2-set_2 ig I-set Ig_2 Ig_6 DUF4692 EphA2_TM Protocadherin Chordopox_A13L Ctr DUF3377 Herpes_glycop DUF2755 DUF6161 MAP17 TMEM154 Baculo_11_kDa LapA_dom

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

1:complement(161070998..161089558)

AA seq 510 aa
MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGE
QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA
DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPS
VTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHIL
HVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTL
GFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL
FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRA
EGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQ
AMNHFVQENGTLRAKPTGNGIYINGRGHLV

NT seq 1533 nt +upstreamnt +downstreamnt
atgcccctgtccctgggagccgagatgtgggggcctgaggcctggctgctgctgctgcta
ctgctggcatcatttacaggccggtgccccgcgggtgagctggagacctcagacgtggta
actgtggtgctgggccaggacgcaaaactgccctgcttctaccgaggggactccggcgag
caagtggggcaagtggcatgggctcgggtggacgcgggcgaaggcgcccaggaactagcg
ctactgcactccaaatacgggcttcatgtgagcccggcttacgagggccgcgtggagcag
ccgccgcccccacgcaaccccctggacggctcagtgctcctgcgcaacgcagtgcaggcg
gatgagggcgagtacgagtgccgggtcagcaccttccccgccggcagcttccaggcgcgg
ctgcggctccgagtgctggtgcctcccctgccctcactgaatcctggtccagcactagaa
gagggccagggcctgaccctggcagcctcctgcacagctgagggcagcccagcccccagc
gtgacctgggacacggaggtcaaaggcacaacgtccagccgttccttcaagcactcccgc
tctgctgccgtcacctcagagttccacttggtgcctagccgcagcatgaatgggcagcca
ctgacttgtgtggtgtcccatcctggcctgctccaggaccaaaggatcacccacatcctc
cacgtgtccttccttgctgaggcctctgtgaggggccttgaagaccaaaatctgtggcac
attggcagagaaggagctatgctcaagtgcctgagtgaagggcagccccctccctcatac
aactggacacggctggatgggcctctgcccagtggggtacgagtggatggggacactttg
ggctttcccccactgaccactgagcacagcggcatctacgtctgccatgtcagcaatgag
ttctcctcaagggattctcaggtcactgtggatgttcttgacccccaggaagactctggg
aagcaggtggacctagtgtcagcctcggtggtggtggtgggtgtgatcgccgcactcttg
ttctgccttctggtggtggtggtggtgctcatgtcccgataccatcggcgcaaggcccag
cagatgacccagaaatatgaggaggagctgaccctgaccagggagaactccatccggagg
ctgcattcccatcacacggaccccaggagccagccggaggagagtgtagggctgagagcc
gagggccaccctgatagtctcaaggacaacagtagctgctctgtgatgagtgaagagccc
gagggccgcagttactccacgctgaccacggtgagggagatagaaacacagactgaactg
ctgtctccaggctctgggcgggccgaggaggaggaagatcaggatgaaggcatcaaacag
gccatgaaccattttgttcaggagaatgggaccctacgggccaagcccacgggcaatggc
atctacatcaatgggcggggacacctggtctga

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