Homo sapiens (human): 81858
Help
Entry
81858 CDS
T01001
Symbol
SHARPIN, AIFID, SIPL1
Name
(RefSeq) SHANK associated RH domain interactor
KO
K20894
shank-associated RH domain-interacting protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04217
Necroptosis
hsa04621
NOD-like receptor signaling pathway
hsa05131
Shigellosis
Network
nt06516
TNF signaling
Element
N01545
Regulation of TNF-NFKB signaling pathway, LUBAC-mediated linear ubiquitination
Disease
H02826
Autoinflammation with episodic fever and immune dysregulation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
81858 (SHARPIN)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
81858 (SHARPIN)
09160 Human Diseases
09171 Infectious disease: bacterial
05131 Shigellosis
81858 (SHARPIN)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
81858 (SHARPIN)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
LUBAC complex
81858 (SHARPIN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sharpin_PH
Zn_ribbon_RanBP
ubiquitin
Motif
Other DBs
NCBI-GeneID:
81858
NCBI-ProteinID:
NP_112236
OMIM:
611885
HGNC:
25321
Ensembl:
ENSG00000179526
UniProt:
Q9H0F6
Q6PJD5
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(144098637..144103773)
Genome browser
AA seq
387 aa
AA seq
DB search
MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLEL
LGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGAT
VEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLA
RAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHV
ALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLL
SAPREAPATGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFI
NAPDRPGCEMCSTQRPCTWDPLAAAST
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atggcgccgccagcgggcggggcggcggcggcggcctcggacttgggctccgccgcagtg
ctcttggctgtgcacgccgcggtgaggccgctgggcgccgggccagacgccgaggcacag
ctgcggaggctgcagctgagcgcggaccctgagcggcctgggcgcttccggctggagctg
ctgggcgcgggacctggggcggttaatttggagtggcccctggagtcagtttcctacacc
atccgaggccccacccagcacgagctacagcctccaccaggagggcctggaaccctcagc
ctgcacttcctcaaccctcaggaagctcagcggtgggcagtcctagtccgaggtgccacc
gtggaaggacagaatggcagcaagagcaactcaccaccagccttgggcccagaagcatgc
cctgtctccctgcccagtcccccggaagcctccacactcaagggccctccacctgaggca
gatcttcctaggagccctggaaacttgacggagagagaagagctggcagggagcctggcc
cgggctattgcaggtggagacgagaagggggcagcccaagtggcagccgtcctggcccag
catcgtgtggccctgagtgttcagcttcaggaggcctgcttcccacctggccccatcagg
ctgcaggtcacacttgaagacgctgcctctgccgcatccgccgcgtcctctgcacacgtt
gccctgcaggtccacccccactgcactgttgcagctctccaggagcaggtgttctcagag
ctcggtttcccgccagccgtgcaacgctgggtcatcggacggtgcctgtgtgtgcctgag
cgcagccttgcctcttacggggttcggcaggatggggaccctgctttcctctacttgctg
tcagctcctcgagaagccccagccacaggacctagccctcagcacccccagaagatggac
ggggaacttggacgcttgtttcccccatcattggggctacccccaggcccccagccagct
gcctccagcctgcccagtccactccagcccagctggtcctgtccttcctgcaccttcatc
aatgccccagaccgccctggctgtgagatgtgtagcacccagaggccctgcacttgggac
ccccttgctgcagcttccacctag
DBGET
integrated database retrieval system
