Homo sapiens (human): 8321
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Entry
8321 CDS
T01001
Symbol
FZD1
Name
(RefSeq) frizzled class receptor 1
KO
K02432
frizzled 1/7
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04916
Melanogenesis
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N01427
WNT5A-ROR signaling pathway
N01440
Wnt signaling modulation, LGR/RSPO
N01441
Wnt signaling modulation, SOST/LRP4
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8321 (FZD1)
04390 Hippo signaling pathway
8321 (FZD1)
04150 mTOR signaling pathway
8321 (FZD1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
8321 (FZD1)
09150 Organismal Systems
09152 Endocrine system
04916 Melanogenesis
8321 (FZD1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8321 (FZD1)
05205 Proteoglycans in cancer
8321 (FZD1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
8321 (FZD1)
05226 Gastric cancer
8321 (FZD1)
05217 Basal cell carcinoma
8321 (FZD1)
05224 Breast cancer
8321 (FZD1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
8321 (FZD1)
09164 Neurodegenerative disease
05010 Alzheimer disease
8321 (FZD1)
05022 Pathways of neurodegeneration - multiple diseases
8321 (FZD1)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
8321 (FZD1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
8321 (FZD1)
G protein-coupled receptors [BR:
hsa04030
]
Frizzled / Smoothened family
8321 (FZD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Frizzled
Fz
7tm_2
Dicty_CAR
Motif
Other DBs
NCBI-GeneID:
8321
NCBI-ProteinID:
NP_003496
OMIM:
603408
HGNC:
4038
Ensembl:
ENSG00000157240
UniProt:
Q9UP38
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:91264433..91271326
Genome browser
AA seq
647 aa
AA seq
DB search
MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPIS
IPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL
EQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTP
SLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPC
EPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSG
CYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWW
VILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVG
LNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVF
SVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDF
TVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
NT seq
1944 nt
NT seq
+upstream
nt +downstream
nt
atggctgaggaggaggcgcctaagaagtcccgggccgccggcggtggcgcgagctgggaa
ctttgtgccggggcgctctcggcccggctggcggaggagggcagcggggacgccggtggc
cgccgccgcccgccagttgacccccggcgattggcgcgccagctgctgctgctgctttgg
ctgctggaggctccgctgctgctgggggtccgggcccaggcggcgggccaggggccaggc
caggggcccgggccggggcagcaaccgccgccgccgcctcagcagcaacagagcgggcag
cagtacaacggcgagcggggcatctccgtcccggaccacggctattgccagcccatctcc
atcccgctgtgcacggacatcgcgtacaaccagaccatcatgcccaacctgctgggccac
acgaaccaggaggacgcgggcctggaggtgcaccagttctaccctctagtgaaagtgcag
tgttccgctgagctcaagttcttcctgtgctccatgtacgcgcccgtgtgcaccgtgcta
gagcaggcgctgccgccctgccgctccctgtgcgagcgcgcgcgccagggctgcgaggcg
ctcatgaacaagttcggcttccagtggccagacacgctcaagtgtgagaagttcccggtg
cacggcgccggcgagctgtgcgtgggccagaacacgtccgacaagggcaccccgacgccc
tcgctgcttccagagttctggaccagcaaccctcagcacggcggcggagggcaccgtggc
ggcttcccggggggcgccggcgcgtcggagcgaggcaagttctcctgcccgcgcgccctc
aaggtgccctcctacctcaactaccacttcctgggggagaaggactgcggcgcaccttgt
gagccgaccaaggtgtatgggctcatgtacttcgggcccgaggagctgcgcttctcgcgc
acctggattggcatttggtcagtgctgtgctgcgcctccacgctcttcacggtgcttacg
tacctggtggacatgcggcgcttcagctacccggagcggcccatcatcttcttgtccggc
tgttacacggccgtggccgtggcctacatcgccggcttcctcctggaagaccgagtggtg
tgtaatgacaagttcgccgaggacggggcacgcactgtggcgcagggcaccaagaaggag
ggctgcaccatcctcttcatgatgctctacttcttcagcatggccagctccatctggtgg
gtgatcctgtcgctcacctggttcctggcggctggcatgaagtggggccacgaggccatc
gaagccaactcacagtattttcacctggccgcctgggctgtgccggccatcaagaccatc
accatcctggcgctgggccaggtggacggcgatgtgctgagcggagtgtgcttcgtgggg
cttaacaacgtggacgcgctgcgtggcttcgtgctggcgcccctcttcgtgtacctgttt
atcggcacgtcctttctgctggccggctttgtgtcgctcttccgcatccgcaccatcatg
aagcacgatggcaccaagaccgagaagctggagaagctcatggtgcgcattggcgtcttc
agcgtgctgtacactgtgccagccaccatcgtcatcgcctgctacttctacgagcaggcc
ttccgggaccagtgggaacgcagctgggtggcccagagctgcaagagctacgctatcccc
tgccctcacctccaggcgggcggaggcgccccgccgcacccgcccatgagcccggacttc
acggtcttcatgattaagtaccttatgacgctgatcgtgggcatcacgtcgggcttctgg
atctggtccggcaagaccctcaactcctggaggaagttctacacgaggctcaccaacagc
aaacaaggggagactacagtctga
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