Homo sapiens (human): 84693
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Entry
84693 CDS
T01001
Symbol
MCEE, GLOD2, MCE, MMCE
Name
(RefSeq) methylmalonyl-CoA epimerase
KO
K05606
methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:
5.1.99.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00280
Valine, leucine and isoleucine degradation
hsa00630
Glyoxylate and dicarboxylate metabolism
hsa00640
Propanoate metabolism
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
Module
hsa_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Network
nt06024
Valine, leucine and isoleucine degradation
Element
N00842
Propanoyl-CoA metabolism
Disease
H00174
Methylmalonic aciduria
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
84693 (MCEE)
00640 Propanoate metabolism
84693 (MCEE)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
84693 (MCEE)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.99 Acting on other compounds
5.1.99.1 methylmalonyl-CoA epimerase
84693 (MCEE)
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Gene cluster
GFIT
Motif
Pfam:
Glyoxalase_4
Glyoxalase
Glyoxalase_3
Ble-like_N
Glyoxalase_6
Glyoxalase_2
Motif
Other DBs
NCBI-GeneID:
84693
NCBI-ProteinID:
NP_115990
OMIM:
608419
HGNC:
16732
Ensembl:
ENSG00000124370
UniProt:
Q96PE7
Structure
PDB
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All DBs
Position
2:complement(71109687..71130229)
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AA seq
176 aa
AA seq
DB search
MARVLKAAAANAVGLFSRLQAPIPTVRASSTSQPLDQVTGSVWNLGRLNHVAIAVPDLEK
AAAFYKNILGAQVSEAVPLPEHGVSVVFVNLGNTKMELLHPLGRDSPIAGFLQKNKAGGM
HHICIEVDNINAAVMDLKKKKIRSLSEEVKIGAHGKPVIFLHPKDCGGVLVELEQA
NT seq
531 nt
NT seq
+upstream
nt +downstream
nt
atggcgcgggtgctgaaggctgcagccgcgaatgccgtagggcttttttccagacttcaa
gctcccattccaacagtaagagcttcttccacatcacagcccttggatcaagtgacaggt
tctgtgtggaacctgggtcgactcaaccatgtagccatagcagtgccagatttggaaaag
gctgcagcattttataagaatattctgggggcccaggtaagtgaagcggtccctcttcct
gaacatggagtatctgttgtttttgtcaacctgggaaataccaagatggaactgcttcat
ccattgggacgtgacagtccaattgcaggttttctgcagaaaaacaaggctggaggaatg
catcacatctgcatcgaggtggataatattaatgcagctgtgatggatttgaaaaaaaag
aagatccgcagtctaagtgaagaggtcaaaataggagcacatggaaaaccagtgattttt
ctccatcctaaagactgtggtggagtccttgtggaactggagcaagcttga
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