Homo sapiens (human): 84867
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Entry
84867 CDS
T01001
Symbol
PTPN5, PTPSTEP, STEP, STEP61
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 5 isoform a
KO
K18018
tyrosine-protein phosphatase non-receptor type 5 [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Network
nt06526
MAPK signaling
Element
N01593
Regulation of GF-RTK-RAS-ERK signaling, PTP
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
84867 (PTPN5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
84867 (PTPN5)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
84867 (PTPN5)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
84867 (PTPN5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase3
Motif
Other DBs
NCBI-GeneID:
84867
NCBI-ProteinID:
NP_008837
OMIM:
176879
HGNC:
9657
Ensembl:
ENSP00000351342.2
UniProt:
P54829
Q86TL3
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(18727928..18792721)
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AA seq
565 aa
AA seq
DB search
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
atgaattatgagggagccaggagtgagagagagaaccacgctgctgatgactccgaggga
ggggccctggacatgtgctgcagtgagaggctaccgggtctcccccagccgatagtgatg
gaggcactggacgaggctgaagggctccaggactcacagagagagatgccgccaccccct
cctccctcgccgccctcagatccagctcagaagccaccacctcgaggcgctgggagccac
tccctcactgtcaggagcagcctgtgcctgttcgctgcctcacagttcctgcttgcctgt
ggggtgctctggttcagcggttatggccacatctggtcacagaacgccacaaacctcgtc
tcctctttgctgacgctcctgaaacagctggaacccacggcctggcttgactctgggacg
tggggagtccccagtctgctgctggtctttctgtccgtgggcctggtcctcgttaccacc
ctggtgtggcacctcctgaggacacccccagagccacccaccccactgccccctgaggac
aggcgccagtcagtgagccgccagccctccttcacctactcagagtggatggaggagaag
atcgaggatgacttcctggacctcgacccggtgcccgagactcctgtgtttgattgtgtg
atggacatcaagcctgaggctgaccccacctcactcaccgtcaagtccatgggtctgcag
gagaggaggggttccaatgtctccctgaccctggacatgtgcactccgggctgcaacgag
gagggctttggctatctcatgtccccacgtgaggagtccgcccgcgagtacctgctcagc
gcctcccgtgtcctccaagcagaagagcttcatgaaaaggccctggaccctttcctgctg
caggcggaattctttgaaatccccatgaactttgtggatccgaaagagtacgacatccct
gggctggtgcggaagaaccggtacaaaaccatacttcccaaccctcacagcagagtgtgt
ctgacctcaccagaccctgacgaccctctgagttcctacatcaatgccaactacatccgg
ggctatggtggggaggagaaggtgtacatcgccactcagggacccatcgtcagcacggtc
gccgacttctggcgcatggtgtggcaggagcacacgcccatcattgtcatgatcaccaac
atcgaggagatgaacgagaaatgcaccgagtattggccggaggagcaggtggcgtacgac
ggtgttgagatcactgtgcagaaagtcattcacacggaggattaccggctgcgactcatc
tccctcaagagtgggactgaggagcgaggcctgaagcattactggttcacatcctggccc
gaccagaagaccccagaccgggcccccccactcctgcacctggtgcgggaggtggaggag
gcagcccagcaggaggggccccactgtgcccccatcatcgtccactgcagtgcagggatt
gggaggaccggctgcttcattgccaccagcatctgctgccagcagctgcggcaggagggt
gtggtggacatcctgaagaccacgtgccagctccgtcaggacaggggcggcatgatccag
acatgcgagcagtaccagtttgtgcaccacgtcatgagcctctacgaaaagcagctgtcc
caccagtccccagaatga
DBGET
integrated database retrieval system
