Homo sapiens (human): 8550
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Entry
8550 CDS
T01001
Symbol
MAPKAPK5, MAPKAP-K5, MK-5, MK5, NCFD, PRAK
Name
(RefSeq) MAPK activated protein kinase 5
KO
K04442
mitogen-activated protein kinase-activated protein kinase 5 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Disease
H02763
Neurocardiofaciodigital syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
8550 (MAPKAPK5)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
8550 (MAPKAPK5)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
MAPKAPK family [OT]
8550 (MAPKAPK5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
Kinase-like
Motif
Other DBs
NCBI-GeneID:
8550
NCBI-ProteinID:
NP_620777
OMIM:
606723
HGNC:
6889
Ensembl:
ENSG00000089022
UniProt:
Q8IW41
LinkDB
All DBs
Position
12:111842228..111902222
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AA seq
473 aa
AA seq
DB search
MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKAR
NEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHF
TEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGDL
MTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPP
FYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLD
HPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPIL
RKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQ
EAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgtcggaggagagcgacatggacaaagccatcaaggaaacttccattttagaagaatac
agtatcaattggactcagaagctgggagctggaattagtggtccagttagagtctgtgta
aagaaatctactcaagaacggtttgcgctgaaaattcttcttgatcgtccaaaagctaga
aatgaggtacgtctgcacatgatgtgtgccacacacccaaacatagttcagattattgaa
gtgtttgctaacagtgtccagtttccccatgagtccagccctagggcccgactcttaatt
gtaatggagatgatggaagggggagagctatttcacagaatcagccagcaccggcacttt
acagagaagcaagccagccaagtaacaaagcagatagctttggctctgcggcactgtcac
ttgttaaacattgcgcacagagacctcaagcctgaaaatctgctttttaaggataactct
ttggatgccccagtgaagttgtgtgactttggatttgccaagattgaccaaggtgacttg
atgacaccccagttcaccccttattatgtagcaccccaggtactggaggcgcaaagaagg
catcagaaggagaaatctggcatcatacctacctcaccgacgccctacacttacaacaag
agctgtgacttgtggtccctaggggtgattatctatgtgatgctgtgcggataccctcct
ttttactccaaacaccacagccggactatcccaaaggatatgcgaagaaagatcatgaca
ggcagttttgagttcccagaggaagagtggagtcagatctcagagatggccaaagatgtt
gtgaggaagctcctgaaggtcaaaccggaggagagactcaccatcgagggagtgctggac
cacccctggctcaattccaccgaggccctggataatgtgctgccttctgctcagctgatg
atggacaaggcagtggttgcaggaatccagcaggctcacgcggaacagttggccaacatg
agaatccaggatctgaaagtcagcctcaaacccctgcactcagtgaacaaccccattctg
cggaagaggaagttacttggcaccaagccaaaggacagtgtctatatccacgaccatgag
aatggagccgaggattccaatgttgccttggaaaaactccgagatgtgattgctcagtgt
attctcccccaggctggtaaaggagagaatgaagatgagaaactgaatgaagtaatgcag
gaggcttggaagtataaccgggaatgcaaactcctaagagatactctgcagagcttcagc
tggaatggtcgtggattcacagataaagtagatcgactaaaactggcagaaattgtgaag
caggtgatagaagagcaaaccacgtcccacgaatcccaataa
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