KEGG T01001: 860

Homo sapiens (human): 860

Entry

860               CDS       T01001

Symbol

RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA

Name

(RefSeq) RUNX family transcription factor 2

K09278

runt-related transcription factor 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04928

Parathyroid hormone synthesis, secretion and action

hsa05202

Transcriptional misregulation in cancer

Network

nt06240 Transcription (cancer)

Element

N00119

MLL-AF4 fusion to transcriptional activation

Disease

H00521

Cleidocranial dysplasia

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    860 (RUNX2)
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    860 (RUNX2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    860 (RUNX2)
Transcription factors [BR:hsa03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   Runt
    860 (RUNX2)

SSDB

Motif

Pfam:

Runt RunxI TFIIA DUF2828 Trp_oprn_chp Med3 Suf BAF1_ABF1 Plasmodium_Vir MAML1_3_TAD1

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

6:45328330..45551082

AA seq 521 aa
MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKS
QAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY

NT seq 1566 nt +upstreamnt +downstreamnt
atggcatcaaacagcctcttcagcacagtgacaccatgtcagcaaaacttcttttgggat
ccgagcaccagccggcgcttcagccccccctccagcagcctgcagcccggcaaaatgagc
gacgtgagcccggtggtggctgcgcaacagcagcagcaacagcagcagcagcaacagcag
cagcagcagcagcaacagcagcagcagcagcaggaggcggcggcggcggctgcggcggcg
gcggcggctgcggcggcggcagctgcagtgccccggttgcggccgccccacgacaaccgc
accatggtggagatcatcgccgaccacccggccgaactcgtccgcaccgacagccccaac
ttcctgtgctcggtgctgccctcgcactggcgctgcaacaagaccctgcccgtggccttc
aaggtggtagccctcggagaggtaccagatgggactgtggttactgtcatggcgggtaac
gatgaaaattattctgctgagctccggaatgcctctgctgttatgaaaaaccaagtagca
aggttcaacgatctgagatttgtgggccggagtggacgaggcaagagtttcaccttgacc
ataaccgtcttcacaaatcctccccaagtagctacctatcacagagcaattaaagttaca
gtagatggacctcgggaacccagaaggcacagacagaagcttgatgactctaaacctagt
ttgttctctgaccgcctcagtgatttagggcgcattcctcatcccagtatgagagtaggt
gtcccgcctcagaacccacggccctccctgaactctgcaccaagtccttttaatccacaa
ggacagagtcagattacagaccccaggcaggcacagtcttccccgccgtggtcctatgac
cagtcttacccctcctacctgagccagatgacgtccccgtccatccactctaccaccccg
ctgtcttccacacggggcactgggcttcctgccatcaccgatgtgcctaggcgcatttca
gatgatgacactgccacctctgacttctgcctctggccttccactctcagtaagaagagc
caggcaggtgcttcagaactgggccctttttcagaccccaggcagttcccaagcatttca
tccctcactgagagccgcttctccaacccacgaatgcactatccagccacctttacttac
accccgccagtcacctcaggcatgtccctcggtatgtccgccaccactcactaccacacc
tacctgccaccaccctaccccggctcttcccaaagccagagtggacccttccagaccagc
agcactccatatctctactatggcacttcgtcaggatcctatcagtttcccatggtgccg
gggggagaccggtctccttccagaatgcttccgccatgcaccaccacctcgaatggcagc
acgctattaaatccaaatttgcctaaccagaatgatggtgttgacgctgatggaagccac
agcagttccccaactgttttgaattctagtggcagaatggatgaatctgtttggcgacca
tattga

DBGET integrated database retrieval system