Homo sapiens (human): 8639
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Entry
8639 CDS
T01001
Symbol
AOC3, HPAO, SSAO, VAP-1, VAP1
Name
(RefSeq) amine oxidase copper containing 3
KO
K00276
primary-amine oxidase [EC:
1.4.3.21
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00260
Glycine, serine and threonine metabolism
hsa00350
Tyrosine metabolism
hsa00360
Phenylalanine metabolism
hsa00410
beta-Alanine metabolism
hsa01100
Metabolic pathways
Drug target
Hydralazine (
DG00261
):
D04458
D08044
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
8639 (AOC3)
00350 Tyrosine metabolism
8639 (AOC3)
00360 Phenylalanine metabolism
8639 (AOC3)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
8639 (AOC3)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.4 Acting on the CH-NH2 group of donors
1.4.3 With oxygen as acceptor
1.4.3.21 primary-amine oxidase
8639 (AOC3)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Cu_amine_oxid
Cu_amine_oxidN2
Cu_amine_oxidN3
DUF1965
Motif
Other DBs
NCBI-GeneID:
8639
NCBI-ProteinID:
NP_003725
OMIM:
603735
HGNC:
550
Ensembl:
ENSG00000131471
Pharos:
Q16853
(Tchem)
UniProt:
Q16853
Q9UEU7
Structure
PDB
PDBj
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Position
17:42851199..42858124
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AA seq
763 aa
AA seq
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MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF
ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP
AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID
QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL
HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW
SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV
YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ
APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH
PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW
AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP
RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF
SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA
DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atgaaccagaagacaatcctcgtgctcctcattctggccgtcatcaccatctttgccttg
gtttgtgtcctgctggtgggcaggggtggagatgggggtgaacccagccagcttccccat
tgcccctctgtatctcccagtgcccagccttggacacaccctggccagagccagctgttt
gcagacctgagccgagaggagctgacggctgtgatgcgctttctgacccagcggctgggg
ccagggctggtggatgcagcccaggcccggccctcggacaactgtgtcttctcagtggag
ttgcagctgcctcccaaggctgcagccctggctcacttggacagggggagccccccacct
gcccgggaggcactggccatcgtcttctttggcaggcaaccccagcccaacgtgagtgag
ctggtggtggggccactgcctcacccctcctacatgcgggacgtgactgtggagcgtcat
ggaggccccctgccctatcaccgacgccccgtgctgttccaagagtacctggacatagac
cagatgatcttcaacagagagctgccccaggcttctgggcttctccaccactgttgcttc
tacaagcaccggggacggaacctggtgacaatgaccacggctccccgtggtctgcaatca
ggggaccgggccacctggtttggcctctactacaacatctcgggcgctgggttcttcctg
caccacgtgggcttggagctgctagtgaaccacaaggcccttgaccctgcccgctggact
atccagaaggtgttctatcaaggccgctactacgacagcctggcccagctggaggcccag
tttgaggccggcctggtgaatgtggtgctgatcccagacaatggcacaggtgggtcctgg
tccctgaagtcccctgtgcccccgggtccagctccccctctacagttctatccccaaggc
ccccgcttcagtgtccagggaagtcgagtggcctcctcactgtggactttctcctttggc
ctcggagcattcagtggcccaaggatctttgacgttcgcttccaaggagaaagactagtt
tatgagataagcctccaagaggccttggccatctatggtggaaattccccagcagcaatg
acgacccgctatgtggatggaggctttggcatgggcaagtacaccacgcccctgacccgt
ggggtggactgcccctacttggccacctacgtggactggcacttccttttggagtcccag
gcccccaagacaatacgtgatgccttttgtgtgtttgaacagaaccagggcctccccctg
cggcgacaccactcagatctctactcgcactactttgggggtcttgcggaaacggtgctg
gtcgtcagatctatgtccaccttgctcaactatgactatgtgtgggatacggtcttccac
cccagtggggccatagaaatacgattctatgccacgggctacatcagctcggcattcctc
tttggtgctactgggaagtacgggaaccaagtgtcagagcacaccctgggcacggtccac
acccacagcgcccacttcaaggtggatctggatgtagcaggactggagaactgggtctgg
gccgaggatatggtctttgtccccatggctgtgccctggagccctgagcaccagctgcag
aggctgcaggtgacccggaagctgctggagatggaggagcaggccgccttcctcgtggga
agcgccacccctcgctacctgtacctggccagcaaccacagcaacaagtggggtcacccc
cggggctaccgcatccagatgctcagctttgctggagagccgctgccccaaaacagctcc
atggcgagaggcttcagctgggagaggtaccagctggctgtgacccagcggaaggaggag
gagcccagtagcagcagcgttttcaatcagaatgacccttgggcccccactgtggatttc
agtgacttcatcaacaatgagaccattgctggaaaggatttggtggcctgggtgacagct
ggttttctgcatatcccacatgcagaggacattcctaacacagtgactgtggggaacggc
gtgggcttcttcctccgaccctataacttctttgacgaagacccctccttctactctgcc
gactccatctacttccgaggggaccaggatgctggggcctgcgaggtcaaccccctagct
tgcctgccccaggctgctgcctgtgcccccgacctccctgccttctcccacgggggcttc
tctcacaactag
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