Homo sapiens (human): 8678
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Entry
8678 CDS
T01001
Symbol
BECN1, ATG6, VPS30, beclin1
Name
(RefSeq) beclin 1
KO
K08334
beclin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04136
Autophagy - other
hsa04137
Mitophagy - animal
hsa04140
Autophagy - animal
hsa04215
Apoptosis - multiple species
hsa04371
Apelin signaling pathway
hsa05010
Alzheimer disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05131
Shigellosis
hsa05167
Kaposi sarcoma-associated herpesvirus infection
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461
Huntington disease
nt06462
Spinocerebellar ataxia
nt06466
Pathways of neurodegeneration
nt06532
Autophagy
Element
N00155
Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N00177
KSHV vBCL2 to autophagy-vesicle nucleation
N00962
Mutation-inactivated ATXN3 to autophagy-vesicle nucleation
N00993
Mutation-caused aberrant Htt to autophagy-vesicle nucleation
N01715
Autophagy-vesicle nucleation/elongation/maturation, PI3P synthesis by PI3KC3-C1
N01717
Regulation of autophagy-vesicle nucleation/elongation/maturation, ATXN3
N01718
Autophagy-vesicle nucleation/elongation/maturation, PACER-RUBCN-PI3KC3-C2
N01719
Autophagy-vesicle nucleation/elongation/maturation, E3 ubiquitin-ligase Malin
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
8678 (BECN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
8678 (BECN1)
04136 Autophagy - other
8678 (BECN1)
04137 Mitophagy - animal
8678 (BECN1)
09143 Cell growth and death
04215 Apoptosis - multiple species
8678 (BECN1)
09160 Human Diseases
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
8678 (BECN1)
09171 Infectious disease: bacterial
05131 Shigellosis
8678 (BECN1)
09164 Neurodegenerative disease
05010 Alzheimer disease
8678 (BECN1)
05014 Amyotrophic lateral sclerosis
8678 (BECN1)
05016 Huntington disease
8678 (BECN1)
05017 Spinocerebellar ataxia
8678 (BECN1)
05022 Pathways of neurodegeneration - multiple diseases
8678 (BECN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
8678 (BECN1)
03029 Mitochondrial biogenesis [BR:
hsa03029
]
8678 (BECN1)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Autophagosome formation proteins
PI3K complex
8678 (BECN1)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Mitophagy factors
Autophagy-related proteins
8678 (BECN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
APG6
APG6_N
BH3
MT
HAUS-augmin3
FPP
V_ATPase_I
Exonuc_VII_L
FapA
DUF4200
GAS
Motif
Other DBs
NCBI-GeneID:
8678
NCBI-ProteinID:
NP_001300927
OMIM:
604378
HGNC:
1034
Ensembl:
ENSG00000126581
Pharos:
Q14457
(Tbio)
UniProt:
Q14457
A0A024R1X5
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(42810132..42824282)
Genome browser
AA seq
450 aa
AA seq
DB search
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEE
ETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTG
DLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQL
QMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ
LELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEW
NEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFF
WDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFN
SEEQWTKALKFMLTNLKWGLAWVSSQFYNK
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atggaagggtctaagacgtccaacaacagcaccatgcaggtgagcttcgtgtgccagcgc
tgcagccagcccctgaaactggacacgagtttcaagatcctggaccgtgtcaccatccag
gaactcacagctccattacttaccacagcccaggcgaaaccaggagagacccaggaggaa
gagactaactcaggagaggagccatttattgaaactcctcgccaggatggtgtctctcgc
agattcatccccccagccaggatgatgtccacagaaagtgccaacagcttcactctgatt
ggggaggcatctgatggcggcaccatggagaacctcagccgaagactgaaggtcactggg
gacctttttgacatcatgtcgggccagacagatgtggatcacccactctgtgaggaatgc
acagatactcttttagaccagctggacactcagctcaacgtcactgaaaatgagtgtcag
aactacaaacgctgtttggagatcttagagcaaatgaatgaggatgacagtgaacagtta
cagatggagctaaaggagctggcactagaggaggagaggctgatccaggagctggaagac
gtggaaaagaaccgcaagatagtggcagaaaatctcgagaaggtccaggctgaggctgag
agactggatcaggaggaagctcagtatcagagagaatacagtgaatttaaacgacagcag
ctggagctggatgatgagctgaagagtgttgaaaaccagatgcgttatgcccagacgcag
ctggataagctgaagaaaaccaacgtctttaatgcaaccttccacatctggcacagtgga
cagtttggcacaatcaataacttcaggctgggtcgcctgcccagtgttcccgtggaatgg
aatgagattaatgctgcttggggccagactgtgttgctgctccatgctctggccaataag
atgggtctgaaatttcagagataccgacttgttccttacggaaaccattcatatctggag
tctctgacagacaaatctaaggagctgccgttatactgttctggggggttgcggtttttc
tgggacaacaagtttgaccatgcaatggtggctttcctggactgtgtgcagcagttcaaa
gaagaggttgagaaaggcgagacacgtttttgtcttccctacaggatggatgtggagaaa
ggcaagattgaagacacaggaggcagtggcggctcctattccatcaaaacccagtttaac
tctgaggagcagtggacaaaagctctcaagttcatgctgacgaatcttaagtggggtctt
gcttgggtgtcctcacaattttataacaaatga
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integrated database retrieval system
