Entry |
|
Name |
Autophagy-vesicle nucleation
|
Definition |
(ULK1+RB1CC1+ATG101+ATG13) -> (BECN1+PIK3C3+ATG14+PIK3R4+AMBRA1) -> PI3P -> (WIPI1,WIPI2,ZFYVE1) |
Expanded |
(8408+9821+60673+9776) -> (8678+5289+22863+30849+55626) -> C04549 -> (55062,26100,53349) |
Class |
|
Type |
Reference
|
Pathway |
|
Gene |
8408 | ULK1; unc-51 like autophagy activating kinase 1 |
9821 | RB1CC1; RB1 inducible coiled-coil 1 |
60673 | ATG101; autophagy related 101 |
9776 | ATG13; autophagy related 13 |
5289 | PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 |
22863 | ATG14; autophagy related 14 |
30849 | PIK3R4; phosphoinositide-3-kinase regulatory subunit 4 |
55626 | AMBRA1; autophagy and beclin 1 regulator 1 |
55062 | WIPI1; WD repeat domain, phosphoinositide interacting 1 |
26100 | WIPI2; WD repeat domain, phosphoinositide interacting 2 |
53349 | ZFYVE1; zinc finger FYVE-type containing 1 |
|
Metabolite |
C04549 | 1-Phosphatidyl-1D-myo-inositol 3-phosphate |
|
Reference |
|
Authors |
Kim KH, Lee MS |
Title |
Autophagy--a key player in cellular and body metabolism. |
Journal |
|
Reference |
|
Authors |
Russell RC, Yuan HX, Guan KL |
Title |
Autophagy regulation by nutrient signaling. |
Journal |
|
LinkDB |
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