Homo sapiens (human): 873 Help Entry 873               CDS       T01001                                  Symbol CBR1, CBR, PG-9-KR, SDR21C1, hCBR1 Name (RefSeq) carbonyl reductase 1   KO K00079   carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa00790   Folate biosynthesis hsa00980   Metabolism of xenobiotics by cytochrome P450 hsa01100   Metabolic pathways hsa05204   Chemical carcinogenesis - DNA adducts hsa05208   Chemical carcinogenesis - reactive oxygen species Network nt06250  DNA adduct formation (cancer)   Element N01381   NNK to DNA adducts N01382   NNK to DNA adducts Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     873 (CBR1)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     873 (CBR1)   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     873 (CBR1)  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis - DNA adducts     873 (CBR1)    05208 Chemical carcinogenesis - reactive oxygen species     873 (CBR1) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.184  carbonyl reductase (NADPH)      873 (CBR1)     1.1.1.189  prostaglandin-E2 9-reductase      873 (CBR1)     1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)      873 (CBR1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  adh_short adh_short_C2 KR Motif Other DBs NCBI-GeneID:  873 NCBI-ProteinID:  NP_001748 OMIM:  114830 HGNC:  1548 Ensembl:  ENSG00000159228 UniProt:  P16152 A0A384NL53 Structure PDBPDBj LinkDB All DBs Position 21:36070024..36073164 Genome browser AA seq 277 aa AA seqDB search MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFH QLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRD VCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK KGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKA TKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atgtcgtccggcatccatgtagcgctggtgactggaggcaacaagggcatcggcttggcc atcgtgcgcgacctgtgccggctgttctcgggggacgtggtgctcacggcgcgggacgtg acgcggggccaggcggccgtacagcagctgcaggcggagggcctgagcccgcgcttccac cagctggacatcgacgatctgcagagcatccgcgccctgcgcgacttcctgcgcaaggag tacgggggcctggacgtgctggtcaacaacgcgggcatcgccttcaaggttgctgatccc acaccctttcatattcaagctgaagtgacgatgaaaacaaatttctttggtacccgagat gtgtgcacagaattactccctctaataaaaccccaagggagagtggtgaacgtatctagc atcatgagcgtcagagcccttaaaagctgcagcccagagctgcagcagaagttccgcagt gagaccatcactgaggaggagctggtggggctcatgaacaagtttgtggaggatacaaag aagggagtgcaccagaaggagggctggcccagcagcgcatacggggtgacgaagattggc gtcaccgttctgtccaggatccacgccaggaaactgagtgagcagaggaaaggggacaag atcctcctgaatgcctgctgcccagggtgggtgagaactgacatggcgggacccaaggcc accaagagcccagaagaaggtgcagagacccctgtgtacttggcccttttgcccccagat gctgagggtccccatggacaatttgtttcagagaagagagttgaacagtggtga

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