Homo sapiens (human): 8767
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Entry
8767 CDS
T01001
Symbol
RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Name
(RefSeq) receptor interacting serine/threonine kinase 2
KO
K08846
receptor-interacting serine/threonine-protein kinase 2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04621
NOD-like receptor signaling pathway
hsa04722
Neurotrophin signaling pathway
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05152
Tuberculosis
Network
nt06521
NLR signaling
Element
N00940
NOD-NFKB signaling pathway
N01112
Salmonella SopE/E2 to NOD-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
8767 (RIPK2)
09156 Nervous system
04722 Neurotrophin signaling pathway
8767 (RIPK2)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
8767 (RIPK2)
05131 Shigellosis
8767 (RIPK2)
05152 Tuberculosis
8767 (RIPK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
8767 (RIPK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
8767 (RIPK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: TKL group
RIPK family [OT]
8767 (RIPK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
CARD
Kdo
Motif
Other DBs
NCBI-GeneID:
8767
NCBI-ProteinID:
NP_003812
OMIM:
603455
HGNC:
10020
Ensembl:
ENSG00000104312
UniProt:
O43353
A0A0S2Z4Z8
Structure
PDB
LinkDB
All DBs
Position
8:89757816..89791064
Genome browser
AA seq
540 aa
AA seq
DB search
MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSER
KDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPL
RFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRS
SKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMY
SVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEI
TFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPET
SRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIIN
PLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTK
PTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM
NT seq
1623 nt
NT seq
+upstream
nt +downstream
nt
atgaacggggaggccatctgcagcgccctgcccaccattccctaccacaaactcgccgac
ctgcgctacctgagccgcggcgcctctggcactgtgtcgtccgcccgccacgcagactgg
cgcgtccaggtggccgtgaagcacctgcacatccacactccgctgctcgacagtgaaaga
aaggatgtcttaagagaagctgaaattttacacaaagctagatttagttacattcttcca
attttgggaatttgcaatgagcctgaatttttgggaatagttactgaatacatgccaaat
ggatcattaaatgaactcctacataggaaaactgaatatcctgatgttgcttggccattg
agatttcgcatcctgcatgaaattgcccttggtgtaaattacctgcacaatatgactcct
cctttacttcatcatgacttgaagactcagaatatcttattggacaatgaatttcatgtt
aagattgcagattttggtttatcaaagtggcgcatgatgtccctctcacagtcacgaagt
agcaaatctgcaccagaaggagggacaattatctatatgccacctgaaaactatgaacct
ggacaaaaatcaagggccagtatcaagcacgatatatatagctatgcagttatcacatgg
gaagtgttatccagaaaacagccttttgaagatgtcaccaatcctttgcagataatgtat
agtgtgtcacaaggacatcgacctgttattaatgaagaaagtttgccatatgatatacct
caccgagcacgtatgatctctctaatagaaagtggatgggcacaaaatccagatgaaaga
ccatctttcttaaaatgtttaatagaacttgaaccagttttgagaacatttgaagagata
acttttcttgaagctgttattcagctaaagaaaacaaagttacagagtgtttcaagtgcc
attcacctatgtgacaagaagaaaatggaattatctctgaacatacctgtaaatcatggt
ccacaagaggaatcatgtggatcctctcagctccatgaaaatagtggttctcctgaaact
tcaaggtccctgccagctcctcaagacaatgattttttatctagaaaagctcaagactgt
tattttatgaagctgcatcactgtcctggaaatcacagttgggatagcaccatttctgga
tctcaaagggctgcattctgtgatcacaagaccactccatgctcttcagcaataataaat
ccactctcaactgcaggaaactcagaacgtctgcagcctggtatagcccagcagtggatc
cagagcaaaagggaagacattgtgaaccaaatgacagaagcctgccttaaccagtcgcta
gatgcccttctgtccagggacttgatcatgaaagaggactatgaacttgttagtaccaag
cctacaaggacctcaaaagtcagacaattactagacactactgacatccaaggagaagaa
tttgccaaagttatagtacaaaaattgaaagataacaaacaaatgggtcttcagccttac
ccggaaatacttgtggtttctagatcaccatctttaaatttacttcaaaataaaagcatg
taa
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