Homo sapiens (human): 8945
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Entry
8945 CDS
T01001
Symbol
BTRC, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
Name
(RefSeq) beta-transducin repeat containing E3 ubiquitin protein ligase
KO
K03362
F-box and WD-40 domain protein 1/11
Organism
hsa
Homo sapiens (human)
Pathway
hsa04114
Oocyte meiosis
hsa04120
Ubiquitin mediated proteolysis
hsa04218
Cellular senescence
hsa04310
Wnt signaling pathway
hsa04340
Hedgehog signaling pathway
hsa04390
Hippo signaling pathway
hsa04710
Circadian rhythm
hsa05131
Shigellosis
hsa05170
Human immunodeficiency virus 1 infection
Network
nt06516
TNF signaling
Element
N00942
Shigella OspG to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
8945 (BTRC)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8945 (BTRC)
04340 Hedgehog signaling pathway
8945 (BTRC)
04390 Hippo signaling pathway
8945 (BTRC)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
8945 (BTRC)
04218 Cellular senescence
8945 (BTRC)
09150 Organismal Systems
09159 Environmental adaptation
04710 Circadian rhythm
8945 (BTRC)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
8945 (BTRC)
09171 Infectious disease: bacterial
05131 Shigellosis
8945 (BTRC)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
8945 (BTRC)
03036 Chromosome and associated proteins [BR:
hsa03036
]
8945 (BTRC)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
SCF complex
Target recognizing subunit (F-box)
8945 (BTRC)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
8945 (BTRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
WD40
Beta-TrCP_D
F-box-like
ANAPC4_WD40
NBCH_WD40
F-box
WD40_like
Nup160
F-box_5
Frtz
DUF4508
DUF6188
Motif
Other DBs
NCBI-GeneID:
8945
NCBI-ProteinID:
NP_378663
OMIM:
603482
HGNC:
1144
Ensembl:
ENSG00000166167
Pharos:
Q9Y297
(Tbio)
UniProt:
Q9Y297
B2R8L3
A0A0S2Z4P6
Q68DS0
Structure
PDB
LinkDB
All DBs
Position
10:101354048..101557313
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AA seq
605 aa
AA seq
DB search
MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
TYISR
NT seq
1818 nt
NT seq
+upstream
nt +downstream
nt
atggacccggccgaggcggtgctgcaagagaaggcactcaagtttatgtgctctatgccc
aggtctctgtggctgggctgctccagcctggcggacagcatgccttcgctgcgatgcctg
tataacccagggactggcgcactcacagctttccagaattcctcagagagagaagactgt
aataatggcgaaccccctaggaagataataccagagaagaattcacttagacagacatac
aacagctgtgccagactctgcttaaaccaagaaacagtatgtttagcaagcactgctatg
aagactgagaattgtgtggccaaaacaaaacttgccaatggcacttccagtatgattgtg
cccaagcaacggaaactctcagcaagctatgaaaaggaaaaggaactgtgtgtcaaatac
tttgagcagtggtcagagtcagatcaagtggaatttgtggaacatcttatatcccaaatg
tgtcattaccaacatgggcacataaactcgtatcttaaacctatgttgcagagagatttc
ataactgctctgccagctcggggattggatcatattgctgagaacattctgtcatacctg
gatgccaaatcactatgtgctgctgaacttgtgtgcaaggaatggtaccgagtgacctct
gatggcatgctgtggaagaagcttatcgagagaatggtcaggacagattctctgtggaga
ggcctggcagaacgaagaggatggggacagtatttattcaaaaacaaacctcctgacggg
aatgctcctcccaactctttttatagagcactttatcctaaaattatacaagacattgag
acaatagaatctaattggagatgtggaagacatagtttacagagaattcactgccgaagt
gaaacaagcaaaggagtttactgtttacagtatgatgatcagaaaatagtaagcggcctt
cgagacaacacaatcaagatctgggataaaaacacattggaatgcaagcgaattctcaca
ggccatacaggttcagtcctctgtctccagtatgatgagagagtgatcataacaggatca
tcggattccacggtcagagtgtgggatgtaaatacaggtgaaatgctaaacacgttgatt
caccattgtgaagcagttctgcacttgcgtttcaataatggcatgatggtgacctgctcc
aaagatcgttccattgctgtatgggatatggcctccccaactgacattaccctccggagg
gtgctggtcggacaccgagctgctgtcaatgttgtagactttgatgacaagtacattgtt
tctgcatctggggatagaactataaaggtatggaacacaagtacttgtgaatttgtaagg
accttaaatggacacaaacgaggcattgcctgtttgcagtacagggacaggctggtagtg
agtggctcatctgacaacactatcagattatgggacatagaatgtggtgcatgtttacga
gtgttagaaggccatgaggaattggtgcgttgtattcgatttgataacaagaggatagtc
agtggggcctatgatggaaaaattaaagtgtgggatcttgtggctgctttggacccccgt
gctcctgcagggacactctgtctacggacccttgtggagcattccggaagagtttttcga
ctacagtttgatgaattccagattgtcagtagttcacatgatgacacaatcctcatctgg
gacttcctaaatgatccagctgcccaagctgaacccccccgttccccttctcgaacatac
acctacatctccagataa
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integrated database retrieval system
