KEGG   Homo sapiens (human): 9076
Entry
9076              CDS       T01001                                 
Symbol
CLDN1, CLD1, ILVASC, SEMP1
Name
(RefSeq) claudin 1
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00742  Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome
Drug target
Lixudebart: D12997
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9076 (CLDN1)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9076 (CLDN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9076 (CLDN1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9076 (CLDN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9076 (CLDN1)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9076 (CLDN1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9076 (CLDN1)
   04147 Exosome [BR:hsa04147]
    9076 (CLDN1)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9076 (CLDN1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9076 (CLDN1)
  Exosomal proteins of colorectal cancer cells
   9076 (CLDN1)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Voltage_CLC Cytochrom_B_C SUR7 DUF2613 DUF2207_C DUF7139
Other DBs
NCBI-GeneID: 9076
NCBI-ProteinID: NP_066924
OMIM: 603718
HGNC: 2032
Ensembl: ENSG00000163347
UniProt: O95832 A5JSJ9
LinkDB
Position
3:complement(190305707..190322446)
AA seq 211 aa
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
NT seq 636 nt   +upstreamnt  +downstreamnt
atggccaacgcggggctgcagctgttgggcttcattctcgccttcctgggatggatcggc
gccatcgtcagcactgccctgccccagtggaggatttactcctatgccggcgacaacatc
gtgaccgcccaggccatgtacgaggggctgtggatgtcctgcgtgtcgcagagcaccggg
cagatccagtgcaaagtctttgactccttgctgaatctgagcagcacattgcaagcaacc
cgtgccttgatggtggttggcatcctcctgggagtgatagcaatctttgtggccaccgtt
ggcatgaagtgtatgaagtgcttggaagacgatgaggtgcagaagatgaggatggctgtc
attgggggtgcgatatttcttcttgcaggtctggctattttagttgccacagcatggtat
ggcaatagaatcgttcaagaattctatgaccctatgaccccagtcaatgccaggtacgaa
tttggtcaggctctcttcactggctgggctgctgcttctctctgccttctgggaggtgcc
ctactttgctgttcctgtccccgaaaaacaacctcttacccaacaccaaggccctatcca
aaacctgcaccttccagcgggaaagactacgtgtga

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