KEGG   Homo sapiens (human): 9076
Entry
9076              CDS       T01001                                 
Symbol
CLDN1, CLD1, ILVASC, SEMP1
Name
(RefSeq) claudin 1
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00742  Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome
Drug target
Lixudebart: D12997
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9076 (CLDN1)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9076 (CLDN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9076 (CLDN1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9076 (CLDN1)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9076 (CLDN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9076 (CLDN1)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9076 (CLDN1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9076 (CLDN1)
   04147 Exosome [BR:hsa04147]
    9076 (CLDN1)
   04515 Cell adhesion molecules [BR:hsa04515]
    9076 (CLDN1)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9076 (CLDN1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9076 (CLDN1)
  Exosomal proteins of colorectal cancer cells
   9076 (CLDN1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9076 (CLDN1)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Voltage_CLC Cytochrom_B_C SUR7 DUF2613 DUF2207_C DUF7139
Other DBs
NCBI-GeneID: 9076
NCBI-ProteinID: NP_066924
OMIM: 603718
HGNC: 2032
Ensembl: ENSG00000163347
UniProt: O95832 A5JSJ9
LinkDB
Position
3:complement(190305707..190322446)
AA seq 211 aa
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
NT seq 636 nt   +upstreamnt  +downstreamnt
atggccaacgcggggctgcagctgttgggcttcattctcgccttcctgggatggatcggc
gccatcgtcagcactgccctgccccagtggaggatttactcctatgccggcgacaacatc
gtgaccgcccaggccatgtacgaggggctgtggatgtcctgcgtgtcgcagagcaccggg
cagatccagtgcaaagtctttgactccttgctgaatctgagcagcacattgcaagcaacc
cgtgccttgatggtggttggcatcctcctgggagtgatagcaatctttgtggccaccgtt
ggcatgaagtgtatgaagtgcttggaagacgatgaggtgcagaagatgaggatggctgtc
attgggggtgcgatatttcttcttgcaggtctggctattttagttgccacagcatggtat
ggcaatagaatcgttcaagaattctatgaccctatgaccccagtcaatgccaggtacgaa
tttggtcaggctctcttcactggctgggctgctgcttctctctgccttctgggaggtgcc
ctactttgctgttcctgtccccgaaaaacaacctcttacccaacaccaaggccctatcca
aaacctgcaccttccagcgggaaagactacgtgtga

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