Homo sapiens (human): 914
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Entry
914 CDS
T01001
Symbol
CD2, LFA-2, SRBC, T11
Name
(RefSeq) T-cell surface antigen CD2 isoform 2 precursor
KO
K06449
T-cell surface glycoprotein CD2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04514
Cell adhesion molecule (CAM) interaction
hsa04517
IgSF CAM signaling
hsa04640
Hematopoietic cell lineage
Drug target
Antithymocyte immunoglobulin (rabbit):
D09190
<JP/US>
Siplizumab:
D05847
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecule (CAM) interaction
914 (CD2)
04517 IgSF CAM signaling
914 (CD2)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
914 (CD2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
914 (CD2)
04515 Cell adhesion molecules [BR:
hsa04515
]
914 (CD2)
04090 CD molecules [BR:
hsa04090
]
914 (CD2)
04091 Lectins [BR:
hsa04091
]
914 (CD2)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
914 (CD2)
Cell adhesion molecules [BR:
hsa04515
]
Immunoglobulin superfamily
SLAM/CD2 family
914 (CD2)
CD molecules [BR:
hsa04090
]
Proteins
914 (CD2)
Lectins [BR:
hsa04091
]
I-type lectins (Siglecs)
914 (CD2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
C2-set
V-set
Ig_2
Ig_3
I-set
TM_ErbB1
DUF8694
EphA2_TM
Por_Secre_tail
LptF_LptG
Tcell_CD4_C
Motif
Other DBs
NCBI-GeneID:
914
NCBI-ProteinID:
NP_001758
OMIM:
186990
HGNC:
1639
Ensembl:
ENSP00000358490.3
UniProt:
P06729
Q53F96
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:116754430..116769229
Genome browser
AA seq
351 aa
AA seq
DB search
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWE
KTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEK
IFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSL
SAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQ
RSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPP
GHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
NT seq
1056 nt
NT seq
+upstream
nt +downstream
nt
atgagctttccatgtaaatttgtagccagcttccttctgattttcaatgtttcttccaaa
ggtgcagtctccaaagagattacgaatgccttggaaacctggggtgccttgggtcaggac
atcaacttggacattcctagttttcaaatgagtgatgatattgacgatataaaatgggaa
aaaacttcagacaagaaaaagattgcacaattcagaaaagagaaagagactttcaaggaa
aaagatacatataagctatttaaaaatggaactctgaaaattaagcatctgaagaccgat
gatcaggatatctacaaggtatcaatatatgatacaaaaggaaaaaatgtgttggaaaaa
atatttgatttgaagattcaagagagggtctcaaaaccaaagatctcctggacttgtatc
aacacaaccctgacctgtgaggtaatgaatggaactgaccccgaattaaacctgtatcaa
gatgggaaacatctaaaactttctcagagggtcatcacacacaagtggaccaccagcctg
agtgcaaaattcaagtgcacagcagggaacaaagtcagcaaggaatccagtgtcgagcct
gtcagctgtccagagaaaggtctggacatctatctcatcattggcatatgtggaggaggc
agcctcttgatggtctttgtggcactgctcgttttctatatcaccaaaaggaaaaaacag
aggagtcggagaaatgatgaggagctggagacaagagcccacagagtagctactgaagaa
aggggccggaagccccaccaaattccagcttcaacccctcagaatccagcaacttcccaa
catcctcctccaccacctggtcatcgttcccaggcacctagtcatcgtcccccgcctcct
ggacaccgtgttcagcaccagcctcagaagaggcctcctgctccgtcgggcacacaagtt
caccagcagaaaggcccgcccctccccagacctcgagttcagccaaaacctccccatggg
gcagcagaaaactcattgtccccttcctctaattaa
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