KEGG   DRUG: Anti-human thymocyte immunoglobulin, rabbit
Entry
D09190                      Drug                                   
Name
Anti-human thymocyte immunoglobulin, rabbit (JAN);
Thymoglobuline (TN)
Product
THYMOGLOBULIN (Genzyme Corporation)
Class
Immunological agent
 DG02019  Interleukin inhibitor
Remark
Therapeutic category: 6399
ATC code: L04AA04
Product: D09190<JP/US>
Efficacy
Immunosuppressant
Target
CD2 [HSA:914] [KO:K06449]
CD3 [HSA:915 916 917] [KO:K06450 K06451 K06452]
CD4 [HSA:920] [KO:K06454]
CD5 [HSA:921] [KO:K06455]
CD7 [HSA:924] [KO:K06457]
CD8 [HSA:925 926] [KO:K06458 K06459]
IL2RA (CD25) [HSA:3559] [KO:K05068]
ITGAL (CD11A) [HSA:3683] [KO:K05718]
  Pathway
hsa04640  Hematopoietic cell lineage
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AA Selective immunosuppressants
     L04AA04 Antithymocyte immunoglobulin (rabbit)
      D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunoglobulins
   Anti-thymocyte Globulin
    D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN)
Drug groups [BR:br08330]
 Immunological agent
  DG02019  Interleukin inhibitor
   D09190  Anti-human thymocyte immunoglobulin, rabbit
Drug classes [BR:br08332]
 Immunological agent
  DG02019  Interleukin inhibitor
   D09190  Anti-human thymocyte immunoglobulin, rabbit
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL2RA (CD25)
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
 Cell surface molecules and ligands
  Cell adhesion molecules: Ig superfamiy
   CD2 family
    CD2
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
  Cell adhesion molecules: other families
   Integrins
    ITGAL (CD11A)
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
  Other cell surface molecules
   CD molecules
    CD3
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
    CD4
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
    CD5
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
    CD7
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
    CD8
     D09190  Anti-human thymocyte immunoglobulin, rabbit (JAN) <JP/US>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09190
Other DBs
PubChem: 96025870
LinkDB

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