Homo sapiens (human): 91801
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Entry
91801 CDS
T01001
Symbol
ALKBH8, ABH8, MRT71, TRM9, TRMT9, TRMT9A
Name
(RefSeq) alkB homolog 8, tRNA methyltransferase
KO
K10770
alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.-
2.1.1.229
]
Organism
hsa
Homo sapiens (human)
Disease
H00768
Autosomal recessive intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
91801 (ALKBH8)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.229 tRNA (carboxymethyluridine34-5-O)-methyltransferase
91801 (ALKBH8)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
tRNA modification factors
Methyltransferases
91801 (ALKBH8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
2OG-FeII_Oxy_2
Methyltransf_11
ALKBH8_N
Methyltransf_25
Methyltransf_12
Methyltransf_31
Methyltransf_23
Methyltransf_8
RRM_1
2OG-FeII_Oxy
MetW
Ubie_methyltran
Motif
Other DBs
NCBI-GeneID:
91801
NCBI-ProteinID:
NP_001287939
OMIM:
613306
HGNC:
25189
Ensembl:
ENSG00000137760
UniProt:
Q96BT7
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(107502727..107565735)
Genome browser
AA seq
664 aa
AA seq
DB search
MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQ
LLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFV
EKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFG
YEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHID
THSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFD
TVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSF
PESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
LGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAE
RRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRS
LVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKG
NPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVI
LQKA
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atggacagcaaccatcaaagtaattacaaactcagtaaaactgagaagaagttcttaagg
aaacagattaaagccaagcatactttgctgagacatgaaggcattgagacagtatcctat
gccactcagagcctggttgttgccaatggtggtttgggtaatggtgtgagtcggaaccag
ctgctcccggttttagagaaatgtggactggtggatgctctcttaatgccacctaacaag
ccgtactcatttgcaagatacagaactacagaagaatctaagagagcctatgttaccctc
aatggaaaagaagtagtggatgatttaggacaaaagatcactctgtatttgaattttgtg
gaaaaagtgcagtggaaggagttgaggcctcaagccttaccaccaggactcatggtagta
gaagaaataatttcttctgaggaggagaaaatgcttttggaaagtgttgattggacagaa
gatacagacaatcaaaactctcaaaaatccttaaaacacagaagagtaaagcattttggt
tatgagttccactatgagaacaacaatgtagataaagataagccattatctgggggtctt
cctgacatttgtgaaagctttttggagaaatggttgaggaaaggttacattaaacataaa
cctgatcaaatgaccataaatcagtatgaacctgggcaaggaattcccgctcatattgat
acacattccgcttttgaggatgagatcgtttctctcagtttggggtcagagattgtcatg
gattttaagcacccagatggcattgcagtgccagttatgttgcctcgtcggagtttgctg
gtgatgacaggagaatctagatacctttggacccatggaatcacgtgcagaaaatttgat
actgttcaagcatctgagagtcttaaaagtggaattatcaccagtgatgttggagactta
actttaagcaagaggggactacgaacatcatttacatttaggaaagtgaggcaaacacct
tgtaactgtagttacccgttggtctgtgatagccagaggaaagagactcccccctcattt
ccagagagtgataaagaagcctcacggctggagcaagagtacgtccatcaggtttatgaa
gagattgctgggcacttcagcagcacaagacataccccttggccgcacattgtggagttt
ttgaaggctttgccaagtggttcaatagtggctgatattggatgtggtaatggaaagtat
cttggcatcaataaggagttatatatgattggttgtgatcgtagccaaaaccttgtggac
atttgtagagagaggcaatttcaggcttttgtctgtgatgcattggcagtaccagtccgc
agtgggtcttgtgatgcctgcatctccattgctgttattcatcattttgcaacagcagag
cgtagagtggcagctctccaagaaattgttcgactcctgagaccaggtgggaaggcactc
atttatgtctgggcaatggaacaagaatataataagcagaagtccaagtatcttagagga
aacagaaatagccaaggaaagaaagaggagatgaacagtgatacctcagtgcagaggtca
cttgtggagcaaatgcgtgacatgggcagtcgagactcggcatcttctgtcccccgcatt
aatgactctcaggaaggaggatgtaattcaaggcaagtttctaattccaagctgcctgtt
catgttaacaggacttctttttattctcaagatgtactggttccctggcaccttaaggga
aatcctgataaaggcaaacctgttgagccatttggtcccataggatcccaggacccaagt
cctgtgtttcatcgttactaccatgtgttccgtgagggagaactggaaggtgcctgcagg
actgtgagtgatgtcagaattctgcaaagctactacgatcaaggaaactggtgtgtgatt
cttcaaaaggcctga
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