Homo sapiens (human): 9415
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Entry
9415 CDS
T01001
Symbol
FADS2, D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13
Name
(RefSeq) fatty acid desaturase 2
KO
K10226
acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:
1.14.19.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00592
alpha-Linolenic acid metabolism
hsa01040
Biosynthesis of unsaturated fatty acids
hsa01100
Metabolic pathways
hsa01212
Fatty acid metabolism
hsa03320
PPAR signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00592 alpha-Linolenic acid metabolism
9415 (FADS2)
01040 Biosynthesis of unsaturated fatty acids
9415 (FADS2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
9415 (FADS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
hsa01004
]
9415 (FADS2)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
1.14.19.3 acyl-CoA 6-desaturase
9415 (FADS2)
Lipid biosynthesis proteins [BR:
hsa01004
]
Desaturase
Front-end
9415 (FADS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FA_desaturase
Cyt-b5
DUF5318
Motif
Other DBs
NCBI-GeneID:
9415
NCBI-ProteinID:
NP_004256
OMIM:
606149
HGNC:
3575
Ensembl:
ENSG00000134824
Pharos:
O95864
(Tbio)
UniProt:
O95864
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All DBs
Position
11:61816203..61867354
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AA seq
444 aa
AA seq
DB search
MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
RALLDIIRSLKKSGKLWLDAYLHK
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atggggaagggagggaaccagggcgagggggccgccgagcgcgaggtgtcggtgcccacc
ttcagctgggaggagattcagaagcataacctgcgcaccgacaggtggctggtcattgac
cgcaaggtttacaacatcaccaaatggtccatccagcacccggggggccagcgggtcatc
gggcactacgctggagaagatgcaacggatgccttccgcgccttccaccctgacctggaa
ttcgtgggcaagttcttgaaacccctgctgattggtgaactggccccggaggagcccagc
caggaccacggcaagaactcaaagatcactgaggacttccgggccctgaggaagacggct
gaggacatgaacctgttcaagaccaaccacgtgttcttcctcctcctcctggcccacatc
atcgccctggagagcattgcatggttcactgtcttttactttggcaatggctggattcct
accctcatcacggcctttgtccttgctacctctcaggcccaagctggatggctgcaacat
gattatggccacctgtctgtctacagaaaacccaagtggaaccaccttgtccacaaattc
gtcattggccacttaaagggtgcctctgccaactggtggaatcatcgccacttccagcac
cacgccaagcctaacatcttccacaaggatcccgatgtgaacatgctgcacgtgtttgtt
ctgggcgaatggcagcccatcgagtacggcaagaagaagctgaaatacctgccctacaat
caccagcacgaatacttcttcctgattgggccgccgctgctcatccccatgtatttccag
taccagatcatcatgaccatgatcgtccataagaactgggtggacctggcctgggccgtc
agctactacatccggttcttcatcacctacatccctttctacggcatcctgggagccctc
cttttcctcaacttcatcaggttcctggagagccactggtttgtgtgggtcacacagatg
aatcacatcgtcatggagattgaccaggaggcctaccgtgactggttcagtagccagctg
acagccacctgcaacgtggagcagtccttcttcaacgactggttcagtggacaccttaac
ttccagattgagcaccacctcttccccaccatgccccggcacaacttacacaagatcgcc
ccgctggtgaagtctctatgtgccaagcatggcattgaataccaggagaagccgctactg
agggccctgctggacatcatcaggtccctgaagaagtctgggaagctgtggctggacgcc
taccttcacaaatga
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